26 completed, 12 unknown, 1 active not recruiting, 1 not yet recruiting. 17 Not applicable, 9 Phase 4, 7 Phase 3, 6 Phase 2, 2 Early Phase 1.
Follow Magnesium Oxide: new trials by email Literature Review of Magnesium Oxide trials Research Report on Magnesium Oxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study of Commercially Available Bowel Preparation Regimens Packaged and Ingested Via Vegan Capsules Sodium picosulfate, magnesium oxide, and citric acid capsules, Polyethylene glycol 3350 with electrolytes capsules - Lower Gastrointestinal Disorder, Tolerance | Early Phase 1 | Not yet recruiting | Ottawa Hospital Research Institute | 80 | 2026-08-01 | 2026-07-14 |
| Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients Magnesium sulfate administration, Magnesium oxide, Magnesium glucoheptonate - Critical Illness | Phase 4 | Recruiting | Scarborough General Hospital | 3853 | 2025-11-25 | 2026-09-24 |
| Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products Dietary supplementation with Microencapsulated Magnesium, Dietary supplementation with Magnesium Oxide, Dietary supplementation with Magnesium Citrate - Healthy Volunteers | Not applicable | Completed | Bionos Biotech S.L. | 40 | 2024-01-28 | 2024-08-20 |
| Effect of Oral Magnesium Supplementation on Type II Diabetes Mellitus Guided by Serum Ionized Magnesium Level Magnesium Oxide tablet 500 mg - Type 2 Diabetes, Magnesium Disorder | Not applicable | Completed | Sultan Qaboos University | 247 | 2023-09-25 | 2025-09-18 |
| Efficacy of Triticum Aestivum Over Vascular Function in Mexican Obese Patients Triticum aestivum, calcined magnesia - Obesity, Vascular Risk | Phase 3 | Completed | Coordinación de Investigación en Salud, Mexico | 20 | 2023-01-03 | 2025-04-30 |
| Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus Drusen Mega®, Sertraline, Placebo - Tinnitus, Subjective, Tinnitus, Bilateral | Phase 2 | Unknown | University of Guadalajara | 58 | 2022-12-01 | 2023-04-07 |
| Bladder and Bowel Dysfunction in Children Polyethylene Glycol 3350, Urotherapy - Bladder and Bowel Dysfunction | Not applicable | Unknown | University of Aarhus | 100 | 2022-09-01 | 2024-05-08 |
| Opioid-Free Pain Protocol After Shoulder Arthroplasty Celecoxib, Pregabalin, Tramadol - Shoulder Arthropathy, Shoulder Pain | Phase 4 | Active not recruiting | Henry Ford Health System | 83 | 2022-06-25 | 2026-02-10 |
| Bowel Preparation in Elective Pediatric Colorectal Surgery Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral - Colostomy, Hirschsprung Disease - Pull Through | Not applicable | Unknown | McMaster University | 81 | 2022-01-01 | 2021-12-09 |
| Combined Antioxidant Therapy on Oxidative Stress in Aqueous and Vitreous Humor of Diabetic Retinopathy Patients Combined antioxidant therapy, Placebo - Diabetic Retinopathy, Oxidative Stress | Phase 2 | Completed | University of Guadalajara | 40 | 2020-03-25 | 2022-04-01 |
| Personalized Colonoscopy Preparation for Patients With Risk Factors for Inadequate Preparation Sodium Picosulfate / Magnesium Oxide / Citric Acid in two split doses + one dose of polyethylene glycol + two Bisacodyl tablets day before the procedure - Inadequate Preparation for Colonoscopy; Personalized Colonoscopy Preparation | Not applicable | Unknown | Rambam Health Care Campus | 600 | 2019-09-01 | 2019-09-25 |
| The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients Placebo Oral Tablet, Magnesium Oxide - Magnesium Deficiency, Heart Failure | Phase 3 | Unknown | Sheba Medical Center | 320 | 2019-08-25 | 2023-12-12 |
| Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy Combined antioxidant therapy, Placebo - Diabetic Retinopathy | Phase 3 | Completed | University of Guadalajara | 132 | 2018-09-26 | 2022-04-01 |
| Bioavailability of Single-dose Magnesium Salts Picometer-ionic form of magnesium chloride, Magnesium citrate or magnesium oxide, Placebo - Bioavailability | Not applicable | Completed | Think Healthy Group, Inc. | 17 | 2018-08-01 | 2024-04-23 |
| Comparison of Clenpiq vs Golytely Bowel Preparation Golytely, Clenpiq - Bowel Preparation Solutions | Phase 4 | Terminated | The Cleveland Clinic | 14 | 2018-07-11 | 2021-03-04 |
| One Week of Magnesium Supplementation Lowers IL-6, Perceived Pain and Increases Post Exercise Blood Glucose in Response to Downhill Running Magnesium oxide, Placebo - Magnesium Deficiency | Not applicable | Completed | University of Worcester | 9 | 2018-06-28 | 2020-01-03 |
| Magnesium and Vascular Stiffness Magnesium Citrate, Magnesium Sulfate, Magnesium Oxide - Vascular Stiffness, Blood Pressure | Not applicable | Unknown | University Medical Center Groningen | 162 | 2018-03-27 | 2018-08-15 |
| A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in Adolescents Magnesium Oxide, Acetaminophen, Zofran ODT 4 MG Disintegrating Oral Tablet - Concussion Post Syndrome | Early Phase 1 | Completed | Corewell Health South | 17 | 2017-09-01 | 2024-11-29 |
| Drug Use-Results Survey on Picoprep® Combination Powder Sodium Picosulfate, Magnesium Oxide and Citric Acid - Bowel Cleansing | Completed | Ferring Pharmaceuticals | 1298 | 2017-08-29 | 2022-01-18 | |
| Effect of Magnesium Supplement in Early Pregnancy After ICSI Magnesium Oxide, Placebo Oral Tablet - ICSI | Phase 3 | Unknown | Ain Shams University | 180 | 2017-06-01 | 2018-01-12 |
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Diabetes Mellitus (3) · Insulin Resistance (3) · Breast Neoplasms (2) · Diabetic Retinopathy (2) · Hot Flashes (2) · Magnesium Deficiency (2) · Pain (2) · Agnosia (1) · Atrial Fibrillation (1) · Calcinosis (1) · Colonic Neoplasms (1) · Critical Illness (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Nephropathies (1) · Dyspepsia (1)
Ferring Pharmaceuticals (3) · University of Guadalajara (3) · Isfahan University of Medical Sciences (2) · Ottawa Hospital Research Institute (2) · Sheba Medical Center (2) · Ain Shams University (1) · Alliance for Clinical Trials in Oncology (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Bionos Biotech S.L. (1) · Chang Gung Memorial Hospital (1) · Coordinación de Investigación en Salud, Mexico (1) · Corewell Health South (1) · Henry Ford Health System (1) · Hvidovre University Hospital (1) · Infante, Javier Molina, M.D. (1)
United States (8) · Mexico (5) · Israel (4) · Canada (3) · Netherlands (3) · Denmark (2) · Iran (2) · Spain (2) · United Kingdom (2) · Belgium (1) · Brazil (1) · Egypt (1) · Italy (1) · Japan (1) · Oman (1)
Adolfo D. Rodriguez-Carrizalez, PhD (1) · Ahmad Esmaeilzadeh, professor (1) · Ahmad Sadeghian, Professor (1) · Alison Edelman, M.D., M.P.H (1) · Andre Knottnerus, MD, PhD (1) · Carol Burke, MD (1) · Charles L. Loprinzi, MD (1) · Christopher Trigger, MD, CAQSM (1) · Dae Kyung Sohn (1) · David Pajuelo Gamez, PhD (1)
PMID 19150702, PMID 20602497, PMID 21271347, PMID 21527040, PMID 22433473, PMID 23827090, PMID 24909487, PMID 25008857, PMID 25723660, PMID 26674497, PMID 31138315, PMID 31205487, PMID 31960275, PMID 32095161, PMID 32313553, PMID 32353962, PMID 34262611, PMID 35253448, PMID 38796500, PMID 42043819