74 completed, 31 unknown, 9 recruiting, 8 terminated. 50 Phase 2, 41 Not applicable, 29 Phase 3, 17 Phase 4, 8 Phase 1.
Follow Carnitine: new trials by email Literature Review of Carnitine trials Research Report on Carnitine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Omega-DEK in Childhood Apraxia of Speech Omega-DEK, L-carnitine, Placebo - Childhood Apraxia of Speech, Verbal Apraxia | Phase 2 | Not yet recruiting | Claudia R. Morris | 34 | 2026-11-01 | 2026-07-29 |
| The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer. L- carnitine - Diabetic Foot Ulcer, Diabetic Foot Ulcer (DFU) | Phase 2 | Recruiting | Ain Shams University | 50 | 2026-09-01 | 2026-08-17 |
| Evaluation of the Clinical Impact of Adjunctive L-carnitine Therapy in Critically Ill Hepatic Patients Admitted to Intensive Care Unit L Carnitine, Standard medical treatment - Hepatic | Phase 4 | Recruiting | Beni-Suef University | 58 | 2026-06-15 | 2026-09-23 |
| DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine - Tinnitus | Phase 2 | Enrolling by invitation | Leading Edge Clinic | 20 | 2026-05-15 | 2026-05-13 |
| Effect of Magnesium and Levocarnitine on Metabolic and Clinical Outcomes in Women With Polycystic Ovarian Syndrome (PCOS) Magnesium 500 mg, Levocarnitine 1000 mg, Placebo - Polycystic Ovary Syndrome (PCOS) | Not applicable | Recruiting | Behnood Abbasi | 84 | 2026-01-30 | 2025-12-23 |
| Effect of L-Carnitine Supplementation in Preterm Neonates L-carnitine, Standard care - Respiratory Distress Syndrome | Not applicable | Recruiting | Muhammad Aamir Latif | 160 | 2026-01-01 | 2026-02-27 |
| Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men L-carnitine - Oligoasthenozoospermia, Male Infertility | Phase 3 | Active not recruiting | South Valley University | 50 | 2026-01-01 | 2026-02-11 |
| Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis Acetyl-l-carnitine, Placebo - Osteoarthritis, Type 2 Diabetes | Not applicable | Completed | Khyber Medical University Peshawar | 100 | 2025-12-01 | 2026-09-17 |
| Oral Carnitine in Heart Failure Patients Levocarnitine - Heart Failure, Carnitine Deficiency | Early Phase 1 | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 20 | 2025-11-12 | 2026-04-20 |
| Levocarnitine for Reducing ESA Requirements in Hemodialysis Patients With Renal Anemia Levocarnitine Injection, Usual ESA-Based Anemia Care - Anemia, Kidney Failure | Phase 4 | Not yet recruiting | Shaikh Zayed Hospital, Lahore | 94 | 2025-09-15 | 2025-09-12 |
| L-Carnitine Protective Effect in Nephrotoxicity L-Carnitine Tartrate, Placebo - Nephrotoxicity | Phase 2 | Recruiting | Tanta University | 46 | 2025-08-10 | 2025-08-12 |
| A Study to Improve Skeletal Muscle in Veterans With HIV w-3 fatty acid, L-carnitine, Control Diet - HIV, Obesity | Not applicable | Recruiting | VA Office of Research and Development | 70 | 2025-07-15 | 2026-06-26 |
| Enteral Nutrition With L-Carnitine for Cachexia in Non-Small Cell Lung Cancer L-Carnitine 4g, Enteral Nutrition - Non-Small Cell Lung Cancer, Cachexia | Not applicable | Not yet recruiting | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 126 | 2025-06-30 | 2025-06-25 |
| Effect of L-carnitine on Disease Activity in Patients With Mild to Moderate Knee Osteoarthritis L-carnitine, Placebo - Knee Osteoarthritis | Phase 2 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 66 | 2025-06-28 | 2026-02-06 |
| Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI L-Carnitine, The standard care for the management of myocardial infarction post PCI - Reperfusion Injury, Myocardial, Myocardial Infarction | Phase 2 | Active not recruiting | Ain Shams University | 76 | 2025-06-01 | 2026-09-01 |
| Effects of Carnitine Supplementation on Exercise-Induced Muscle Damage: A Randomized Controlled Trial L-Carnitine, Placebo - Recovery Methods, Exercise and Recovery | Not applicable | Completed | Istanbul Sabahattin Zaim University | 30 | 2025-05-09 | 2026-03-25 |
| Peritoneal Ultrafiltration in Cardio Renal Syndrome. PolyCore (Polydextrin, L-Carnitine, D-xylitol) - Congestive Heart Failure | Phase 1 / Phase 2 | Recruiting | Iperboreal Pharma Srl | 84 | 2025-04-16 | 2025-05-16 |
| Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria L-carnitine - Phenylketonuria | Phase 4 | Active not recruiting | Mansoura University | 176 | 2025-02-01 | 2025-04-04 |
| L-carnitine Supplementation in Rheumatoid Arthritis Patients Carnitine, Disease-modifying anti-rheumatic drugs - Rheumatoid Arthritis (RA) | Phase 2 | Recruiting | German University in Cairo | 60 | 2024-12-31 | 2025-01-07 |
| Enhancing the Effects of Alcohol Treatment With L-Carnitine L-carnitine - Alcohol Use Disorder | Phase 1 | Completed | Brown University | 24 | 2024-09-27 | 2025-06-15 |
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HIV Infections (14) · Kidney Failure, Chronic (7) · Acquired Immunodeficiency Syndrome (6) · Fatigue (6) · Insulin Resistance (6) · Systemic carnitine deficiency (6) · Heart Failure (5) · Dyslipidemias (4) · Motor Activity (4) · Muscular Atrophy, Spinal (4) · Obesity (4) · Polycystic Ovary Syndrome (4) · Anemia (3) · Autistic Disorder (3) · Breast Neoplasms (3)
Ain Shams University (9) · Iperboreal Pharma Srl (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Gilead Sciences (4) · Tanta University (4) · Assiut University (3) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (3) · Gdansk University of Physical Education and Sport (3) · University of Utah (3) · Alexandria University (2) · Maastricht University Medical Center (2) · Mahidol University (2) · Montefiore Medical Center (2) · National Taiwan University Hospital (2) · Poznan University of Physical Education (2)
United States (44) · Egypt (23) · Canada (10) · Iran (8) · Italy (5) · Puerto Rico (5) · Bangladesh (4) · France (4) · Germany (4) · China (3) · Pakistan (3) · Poland (3) · Brazil (2) · Israel (2) · Mexico (2)
Mario Bonomini, MD (3) · Scott Hammer (3) · Arduino Arduini, MD (2) · Kathryn J Swoboda, M.D. (2) · Lars Berglund, MD, PhD (2) · Ricardo Cruciani, MD, PhD (2) · Robert Olek, PhD (2) · Sandra P Reyna, M.D. (2) · Acary Souza Bulle Oliveira, MD, PhD (1) · Alaa M Ismail, M.D (1) · Alaleh Gheisari (1) · Alan E Jones, MD (1) · Aldo Sgaravatti, MD (1) · Alice Shapiro, PhD (1) · Amer M Johri, MD (1)
PMID 36472884, PMID 10190267, PMID 10650325, PMID 10859281, PMID 10919968, PMID 11023461, PMID 11277825, PMID 11326085, PMID 11529691, PMID 11729302, PMID 11834528, PMID 11895451, PMID 11975885, PMID 12195349, PMID 12213433, PMID 12417828, PMID 12421890, PMID 12430089, PMID 12485966, PMID 12686036, PMID 12730697, PMID 12829554, PMID 12867219, PMID 12908852, PMID 12972104, PMID 14607021, PMID 14666956, PMID 15007110, PMID 15031785, PMID 15141377, PMID 15295692, PMID 15331429, PMID 15478042, PMID 15553600, PMID 15591005, PMID 15755765, PMID 15849374, PMID 15855667, PMID 16003294, PMID 16034009, PMID 16249704, PMID 16377285, PMID 16384561, PMID 16461820, PMID 16554528, PMID 16832163, PMID 16891287, PMID 16903986, PMID 16907655, PMID 17039901
2009 (1), P30CA124435 (1), R21AA029033 (1), U10CA023318 (1), U24CA196173 (1), UG1CA189955 (1)