1426 completed. 1426 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1426 | Completed 1426 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stereotactic Radiotherapy Treatment for Treatment-Resistant Depression ZAP-X - Treatment-Resistant Depression, Depressive Disorder | Not applicable | Completed | Capital Medical University | 9 | 2026-01-26 | 2026-08-10 |
| NQ Square TMS for Major Depressive Disorder: One Day, Three Sessions in Adults Active Accelerated rTMS Treatment, Sham Accelerated rTMS Treatment - Major Depressive Disorder | Not applicable | Completed | NeuroQore Inc. | 56 | 2026-01-15 | 2026-11-03 |
| The Effect of Cognitive Behavioral Psychoeducation on Internalized Stigma in Individuals With Bipolar Disorder Cognitive-behavioral based psychoeducation program, Standard Care (in control arm) - Bipolar Disorder (BD), Internalized Stigma | Not applicable | Completed | Eskisehir Osmangazi University | 43 | 2026-01-01 | 2026-07-29 |
| The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Support Psychodramatic Role-Playing Childbirth Education, Standard Childbirth Education - Postpartum Depression, Maternal Self-Efficacy | Not applicable | Completed | Istanbul University - Cerrahpasa | 57 | 2025-10-31 | 2026-04-02 |
| Effects of ACT-Based Psychoeducation on Caregivers of Individuals With Mental Disorders ACT-Based Psychoeducation Program - Caregiver Burden, Mental Disorders | Not applicable | Completed | Zeynep Özkök | 64 | 2025-10-06 | 2026-06-11 |
| Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan Metacognitive Training (MCT), Traditional Chinese version - Schizophrenia, Major Depressive Disorder | Not applicable | Completed | ZI-YU LIN | 18 | 2025-10-03 | 2025-12-10 |
| Pilot Study of Brief Culturally Adapted Behavioral Activation for Adults With Depression in Primary Care Setting brief culturally adapted behavioral activation - Depression in Adults | Not applicable | Completed | Gadjah Mada University | 12 | 2025-09-22 | 2026-07-21 |
| Arts-based Social Prescribing for Mental Health Art Prescription - Mental Health Issue, Anxiety Disorders | Not applicable | Completed | KAVADIA ELENI | 541 | 2025-09-04 | 2026-03-18 |
| REM Sleep Disruption and Its Potential Uses in Depression Management REM-Contingent Smartwatch Haptic Stimulation, Smartwatch Sleep Monitoring and Smart Alarm - Depression / Major Depressive Disorder, Depressed Mood | Not applicable | Completed | WAKEZ HEALTH TECH ECOSYSTEM SRL | 208 | 2025-09-01 | 2026-10-23 |
| Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race Intervention Name: Fermented milk containing Lacticaseibacillus paracasei strain Shirota. Intervention Name: Non-fermented milk (placebo), Non-fermented milk (placebo) - Respiratory Tract Infections (RTI), Mucosal Immunity | Not applicable | Completed | Federal University of São Paulo | 80 | 2025-08-13 | 2026-10-15 |
| Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course dialectical behavior therapy - Depression - Major Depressive Disorder, Anxiety | Not applicable | Completed | University of Windsor | 41 | 2025-07-20 | 2026-11-03 |
| Reduction of Anticholinergic Medications Among Persons With Schizophrenia or Other Psychiatric Disorders Reduction of anticholinergic medication - Schizophenia Disorder, Schizoaffective Disorder | Not applicable | Completed | University of Pittsburgh | 53 | 2025-07-16 | 2026-06-04 |
| Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents ViraBrite nudges - Suicide, Mental Health Disorder | Not applicable | Completed | Ksana Health | 24 | 2025-07-16 | 2026-08-12 |
| Virtual Reality-Based Psychotherapeutic and Psychoeducational Intervention for Anxiety and Depression in Children, Adolescents, and Adults Virtual Reality-Based Psychotherapeutic Program - Anxiety Disorders, Depressive Disorders | Not applicable | Completed | Istanbul Aydın University | 40 | 2025-07-09 | 2025-11-26 |
| The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment prenatal yoga - Depression, Postpartum | Not applicable | Completed | Muş Alparslan University | 80 | 2025-07-07 | 2026-10-20 |
| Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding the psychoeducation intervention program, routine care - Postpartum Depression, Psychoeducation | Not applicable | Completed | Yasemin Ozhuner | 88 | 2025-07-02 | 2026-01-07 |
| Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy Propofol, Ketofol - Major Depressive Disorder | Not applicable | Completed | Fauji Foundation Hospital | 80 | 2025-07-01 | 2025-12-12 |
| Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder Electroconvulsive Therapy, Ketamine - Electroconvulsive Therapy, Intravenous Ketamine | Not applicable | Completed | Tanta University | 70 | 2025-07-01 | 2026-04-13 |
| Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression Fluoxetine (drug), Magnesium - Major Depressive Disorder (MDD) | Not applicable | Completed | Hasanuddin University | 40 | 2025-07-01 | 2026-04-09 |
| The Brain-Heart-Gut Connection Transcranial Magnetic Stimulation (TMS), High-definition transcranial direct current stimulation (HD-tDCS) - Major Depression, Functional Dyspepsia | Not applicable | Completed | University of Bern | 34 | 2025-06-01 | 2026-04-08 |
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Depressive Disorder, Major (613) · Depression (427) · Bipolar Disorder (364) · Depressive Disorder (227) · Depression, Postpartum (220) · Anxiety Disorders (177) · Schizophrenia (138) · Psychotic Disorders (92) · Mental Disorders (72) · Depressive Disorder, Treatment-Resistant (66) · Stress Disorders, Post-Traumatic (49) · Psychological Well-Being (42) · Substance-Related Disorders (32) · Motor Activity (27)
Mental Disorders (1354) · Depressive Disorder (836) · Behavior (553) · Behavioral Symptoms (448) · Bipolar and Related Disorders (364) · Urogenital Diseases (227) · Female Urogenital Diseases and Pregnancy Complications (225) · Pregnancy Complications (221) · Puerperal Disorders (217) · Schizophrenia Spectrum and Other Psychotic Disorders (155) · Pathological Conditions, Signs and Symptoms (154) · Signs and Symptoms (105) · Nervous System Diseases (99) · Neurologic Manifestations (65)
Cognitive Behavioral Therapy (59) · Therapeutics (53) · Transcranial Magnetic Stimulation (48) · Transcranial Direct Current Stimulation (25) · Exercise (20) · Escitalopram (19) · Mindfulness-Based Cognitive Therapy (15) · Palliative Care (14) · Standard of Care (13) · Fluoxetine (12) · Sertraline (12) · Interpersonal Psychotherapy (11) · Psychotherapy (11) · Ketamine (10) · Lithium (10)
Massachusetts General Hospital (49) · Centre for Addiction and Mental Health (40) · University of Michigan (24) · Stanford University (23) · New York State Psychiatric Institute (21) · VA Office of Research and Development (21) · University of California, San Francisco (18) · University of Washington (18) · Dartmouth-Hitchcock Medical Center (17) · University of Pittsburgh (17) · Mclean Hospital (15) · University of Pennsylvania (14) · McMaster University (13) · Northwestern University (12) · University of North Carolina, Chapel Hill (12)
United States (668) · Canada (125) · Germany (62) · Turkey (Türkiye) (51) · France (46) · China (41) · Denmark (38) · United Kingdom (34) · Spain (31) · Sweden (23) · Taiwan (22) · Australia (20) · Israel (18) · Norway (17) · Hong Kong (15)
Martha Sajatovic, MD (6) · Ryan Van Lieshout, MD, PhD (6) · Daniel Blumberger, MD (5) · Arun Ravindran, MD, PhD (4) · Daniel Blumberger, MD, MSc (4) · Ashley E Mason, PhD (3) · Brandon Gaudiano, PhD (3) · Daniel F Gros, PhD MA BS (3) · Darius Tandon, PhD (3) · David M Kreindler, MD (3) · Dror Ben-Zeev, PhD (3) · Flavio Frohlich, PhD (3) · Herbert Y Meltzer, M.D. (3) · Leslie Swanson, Ph.D. (3)
PMID 42383885, PMID 27488181, PMID 34286512, PMID 34817851, PMID 34874888, PMID 38819882, PMID 22581378, PMID 25083802, PMID 25374288, PMID 26604001, PMID 26903254, PMID 27227751, PMID 27780336, PMID 28057609, PMID 28231791, PMID 28709880, PMID 29701939, PMID 30854751, PMID 32046986, PMID 32090783, PMID 33884617, PMID 34131914, PMID 34232578, PMID 38743265, PMID 39625263, PMID 11765093, PMID 11939866, PMID 12096176, PMID 12472325, PMID 14702250, PMID 15005752, PMID 15067160, PMID 15110730, PMID 15183601, PMID 15213794, PMID 15330403, PMID 15349007, PMID 15465989, PMID 15541061, PMID 15569893, PMID 15677618, PMID 15723025, PMID 15725966, PMID 15821196, PMID 15876903, PMID 15898966, PMID 15939840, PMID 15950022, PMID 15960566, PMID 16023735
2019 (2), K23DA050808 (2), R01MH039188 (2), R01MH042931 (2), R01MH064662 (2), R01MH077210 (2), R01MH101547 (2), R21HD101786 (2), R21MD011320 (2), R34AT011221 (2), R34MH083866 (2), R34MH103568 (2), R34MH117198 (2), R61MH118405 (2), U19MH095687 (2)