18 completed, 8 unknown, 5 recruiting, 3 enrolling by invitation. 16 Not applicable, 5 Phase 4, 4 Phase 2, 3 Phase 3, 1 Phase 1.
Follow Lumbar Disc Disease: new trials by email Literature Review of Lumbar Disc Disease trials Research Report on Lumbar Disc Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical and MRI Findings in Lumbar Disc Disease Lumbar Disc Disease, Low Back Pain | Not yet recruiting | Assiut University | 96 | 2026-04-01 | 2026-04-08 | |
| Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain Fluoroscopy-guided lumbar transforaminal epidural steroid injection - Lumbar Disc Disease, Radiculopathy Lumbar | Not yet recruiting | Mersin University | 120 | 2026-04-01 | 2026-03-27 | |
| AuriculoTherapy NeuroImaging Cryo-auriculotherapy, Sham auriculotherapy, Experimental auricular stimulation - Low Back Pain, Chronic Low-back Pain | Not applicable | Recruiting | Keith M Vogt | 60 | 2025-07-30 | 2026-02-18 |
| Development of a Fascial Training Based Mobile Application and Investigation of Its Effectiveness in Patients With Disc Herniation fascial exercise home brochure, Fascial exercise based mobile application, lumbal stabilizasyon home brochure - Lumbar Disc Disease, Lumbal Disc Herniation | Not applicable | Enrolling by invitation | Baskent University | 1 | 2025-02-01 | 2025-09-23 |
| LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF) LDGraft, Allograft Bone - Degenerative Disc Disease, Lumbar Disc Disease | Phase 1 / Phase 2 | Recruiting | Locate Bio Pty Ltd | 40 | 2024-11-12 | 2026-08-26 |
| RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain Discogenic Low Back Pain, Intervertebral Disc Degeneration | Enrolling by invitation | EPC Education s.r.o. | 120 | 2024-10-01 | 2026-01-14 | |
| PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study Spinoplasty with Platelet Rich Plasma - Lower Back Pain Chronic, Lumbar Disc Disease | Phase 2 | Completed | Allmed Medical Center | 35 | 2024-09-15 | 2025-12-08 |
| The Effect of Mediclore as an Anti-adhesion Agent and Safety in Full-endoscopic Spine Surgery: a Preliminary Study Mediclore, Normal Saline - Lumbar Disc Disease, Epidural Fibrosis | Phase 4 | Unknown | King Chulalongkorn Memorial Hospital | 78 | 2023-10-01 | 2023-09-14 |
| NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study NOCISCAN-LS Disc MR Spectroscopy - Lumbar Disc Disease | Unknown | Nocimed, LLC | 240 | 2023-04-01 | 2022-07-29 | |
| Effects of Kinesio Taping on Pain, Endurance, Proprioception, Mobility and Disability in Lumbar Disc Herniation Routine Treatment + I Taping, Routine Treatment + Star Taping, Routine Treatment - Lumbar Disc Herniation, Lumbar Disc Disease | Not applicable | Completed | Sevtap Günay | 90 | 2023-03-15 | 2025-01-15 |
| Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain Physical Therapy - Low Back Pain, Lumbar Disc Disease | Completed | Afyonkarahisar Health Sciences University | 160 | 2022-12-15 | 2023-02-01 | |
| A Post Market Surveillance on INFUSE Bone Graft INFUSE™ Bone Graft - Intervertebral Disc Degeneration, Spinal Fusion | Recruiting | Medtronic Spinal and Biologics | 600 | 2022-08-10 | 2025-03-20 | |
| Ultrasound-Guided vs. Surgeon-Performed (Free-hand) Erector Spinae Plane Block US-guided ESPB., Surgeon-performed (Free-hand) ESPB. - Lumbar Disc Herniation, Lumbar Disc Disease | Not applicable | Completed | Medipol University | 102 | 2022-08-01 | 2026-03-10 |
| A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD) BRTX-100, Saline - Lumbar Disc Disease | Phase 2 | Recruiting | BioRestorative Therapies | 99 | 2022-06-30 | 2025-08-26 |
| Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery Ropivacaine Hydrochloride Injection, Sodium chloride - Spondylolisthesis, Lumbar Disc Herniation | Phase 4 | Completed | Ilse van de Wijgert | 76 | 2022-06-01 | 2024-04-17 |
| GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries General anesthetic, SA + ESP - Lumbar Disc Herniation, Lumbar Disc Disease | Phase 3 | Enrolling by invitation | Hospital for Special Surgery, New York | 142 | 2022-03-22 | 2026-04-28 |
| Injection of Autologous Bone Marrow Aspirate in Patients With Degenerative Disc Disease. Autologous bone marrow aspirate injected intradiscal after microdiscectomy, Discectomy only - Lumbar Disc Disease | Unknown | New York Presbyterian Hospital | 60 | 2021-11-01 | 2021-12-21 | |
| Efficacy of the ATLAS Medical Device on Pain in Patients With Low Back Pain Due to Lumbar Disc Disease Visual analog scale, Mac Gill Pain Questionnaire, Roland and Morris Disability Questionnaire - Lumbar Disc Disease | Not applicable | Terminated | GCS Ramsay Santé pour l'Enseignement et la Recherche | 3 | 2021-08-18 | 2022-06-23 |
| Study of the Long-Term Outcomes of Posterior Spinal Fixation With the Karma Device Karma Posterior Fixation Device - Lumbar Disc Disease | Completed | Spinal Elements | 20 | 2021-08-15 | 2025-06-29 | |
| Erector Spinae Plane Block in Spine Surgeries erector spinae block for group E - Lumbar Disc Disease | Phase 4 | Unknown | Ain Shams University | 44 | 2021-01-22 | 2022-02-18 |
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Intervertebral disc disease (42) · Intervertebral Disc Displacement (13) · Intervertebral Disc Degeneration (10) · Spinal Stenosis (9) · Radiculopathy (7) · Low Back Pain (6) · Sciatica (3) · Spinal Diseases (3) · Spondylolisthesis (3) · Hypertension (2) · Pain, Postoperative (2) · Spondylosis (2) · Alopecia (1) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1)
Bone Diseases (25) · Musculoskeletal Diseases (25) · Spinal Diseases (22) · Pathological Conditions, Signs and Symptoms (20) · Neurologic Manifestations (14) · Pathological Conditions, Anatomical (14) · Signs and Symptoms (14) · Hernia (13) · Pain (13) · Nervous System Diseases (10) · Neuromuscular Diseases (10) · Peripheral Nervous System Diseases (10) · Back Pain (6) · Pathologic Processes (5) · Mental Disorders (3)
Acetaminophen (2) · Ropivacaine (2) · Saline Solution (2) · Sodium Chloride (2) · Anesthetics, General (1) · Bupivacaine (1) · Control Groups (1) · Dipyrone (1) · Glucose (1) · Ibuprofen (1) · Injections, Epidural (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Magnetic Resonance Spectroscopy (1) · Parapsychology (1)
Cantonal Hospital of St. Gallen (2) · GCS Ramsay Santé pour l'Enseignement et la Recherche (2) · Hospital for Special Surgery, New York (2) · Medipol University (2) · Seikagaku Corporation (2) · University of Valencia (2) · Afyonkarahisar Health Sciences University (1) · Ain Shams University (1) · Akdeniz University (1) · Allina Health System (1) · Allmed Medical Center (1) · American British Cowdray Medical Center (1) · Assiut University (1) · Baskent University (1) · BioRestorative Therapies (1)
United States (16) · Turkey (Türkiye) (9) · France (3) · Spain (3) · Switzerland (2) · Australia (1) · Egypt (1) · Germany (1) · Lebanon (1) · Mexico (1) · Netherlands (1) · Palestinian Territories (1) · Poland (1) · Romania (1) · Slovakia (1)
Nicolai Maldaner, MD (2) · Catherine Himo Gang (1) · Christian Cerecedo, MD (1) · Christopher Alcala-Marquez, MD (1) · Eduardo Galvan Hernandez, MD (1) · Harvinder Sandhu, MD (1) · Jad G Khalil, MD (1) · Jason Lipitz, MD (1) · Joseph Maarrawi, MD, PhD (1) · Keith M Vogt, MD, PhD (1) · Leopoldo Torres Vyera, MD (1)
PMID 10214567, PMID 15950689, PMID 18164459, PMID 20542472, PMID 25032676, PMID 27646404, PMID 30100096, PMID 30217693, PMID 31042663, PMID 31444917, PMID 32708699, PMID 33974372, PMID 34033596, PMID 34042414, PMID 34352935, PMID 35015137, PMID 35800997, PMID 37182704, PMID 40601485, PMID 41511609