14 withdrawn. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Withdrawn 14 |
Follow Leg Injuries: new trials by email Literature Review of Leg Injuries trials Research Report on Leg Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction Tranexamic Acid (TXA), Placebo - ACL Injury, ACL Tears | Phase 4 | Withdrawn | Campbell Clinic | 2026-04-01 | 2026-03-03 | |
| Single Shot Exparel vs Catheters in Lower Extremity Trauma Bupivacaine, Exparel + Bupivacaine - Fracture Dislocation of Ankle Joint, Fracture Leg | Phase 4 | Withdrawn | George Washington University | 2025-09-12 | 2026-09-24 | |
| Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture PENG block and cryoablation, fascia iliaca compartment block - Hip Fractures | Phase 4 | Withdrawn | University of Minnesota | 2024-10-01 | 2026-10-16 | |
| Supracondylar Distal Femur Fractures and Abaloparatide Abaloparatide, Placebo - Femoral Fractures | Phase 4 | Withdrawn | Daniel Horwitz | 2024-06-01 | 2024-05-01 | |
| Duloxetine Tibial Plateau Duloxetine, Placebo, Standard of care (SOC) for tibial plateau surgery - Tibial Plateau Fracture, Pain, Postoperative | Phase 4 | Withdrawn | Boston Medical Center | 2022-10-01 | 2022-11-21 | |
| CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF CBD, Placebo - Ankle Fractures, Tibia Fracture | Phase 4 | Withdrawn | NYU Langone Health | 2021-10-01 | 2022-01-28 | |
| EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture EXPAREL, Ropivacaine, Bupivacaine Hydrochloride - Hip Fractures, Intertrochanteric Fractures | Phase 4 | Withdrawn | Pacira Pharmaceuticals, Inc | 2019-08-26 | 2020-02-27 | |
| GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture Rocuronium, Sugammadex, Normal saline - Hip Fractures, Anesthesia, Spinal | Phase 4 | Withdrawn | Loyola University | 2017-07-19 | 2019-08-20 | |
| Effects of Intraarticular IL1-Ra on Pain and Inflammatory Mediators After Knee Arhroscopy Anakinra 100 mg in 2 ml saline IA - Knee Injuries | Phase 4 | Withdrawn | Oslo University Hospital | 2016-03-01 | 2021-06-11 | |
| The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures Tranexamic Acid, Placebo - Hip Fracture, Blood Loss | Phase 4 | Withdrawn | Hospital for Special Surgery, New York | 2015-12-01 | 2017-03-28 | |
| Effect of Loading of Midazolam or Dexmedetomidine on Hemodynamics dexmedetomidine group, midazolam group - Knee Injuries | Phase 4 | Withdrawn | Konkuk University Medical Center | 2015-07-01 | 2021-04-20 | |
| Obturator Nerve Block in Patients With Hip Fracture Bupivacaine, Saline - Hip Fractures | Phase 4 | Withdrawn | University of Aarhus | 2015-03-01 | 2015-09-14 | |
| Preoperative Levosimendan and Heart Failure Levosimendan, Placebo - Heart Failure, Hip Fracture | Phase 4 | Withdrawn | Sykehuset i Vestfold HF | 2011-04-01 | 2012-12-17 | |
| Comparing the Efficacy of the ConvaTec Engenex® Negative Pressure Wound Therapy Device to Moist Wound Therapy Convatec engenex negative pressure wound therapy - Diabetes, Foot Wound | Phase 4 | Withdrawn | Georgetown University | 2010-05-01 | 2012-03-09 |
Hip Fractures (6) · Femoral Fractures (2) · Knee Injuries (2) · Ankle Fractures (1) · Anterior Cruciate Ligament Injuries (1) · Diabetes Mellitus (1) · Foot Injuries (1) · Fractures, Bone (1) · Heart Failure (1) · Hemorrhage (1) · Inflammation (1) · Pain (1) · Pain, Postoperative (1) · Tibial Fractures (1) · Tibial Plateau Fractures (1)
Wounds and Injuries (14) · Fractures, Bone (9) · Femoral Fractures (6) · Hip Injuries (6) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Knee Injuries (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Ankle Injuries (1) · Cardiovascular Diseases (1) · Endocrine System Diseases (1) · Glucose Metabolism Disorders (1) · Heart Diseases (1)
Bupivacaine (3) · Tranexamic Acid (2) · Cryosurgery (1) · Dexmedetomidine (1) · Duloxetine Hydrochloride (1) · Interleukin 1 Receptor Antagonist Protein (1) · Midazolam (1) · Rocuronium (1) · Ropivacaine (1) · Saline Solution (1) · Simendan (1) · Sodium Chloride (1) · Standard of Care (1) · Sugammadex (1) · Sugars (1)
Boston Medical Center (1) · Campbell Clinic (1) · Daniel Horwitz (1) · George Washington University (1) · Georgetown University (1) · Hospital for Special Surgery, New York (1) · Konkuk University Medical Center (1) · Loyola University (1) · NYU Langone Health (1) · Oslo University Hospital (1) · Pacira Pharmaceuticals, Inc (1) · Sykehuset i Vestfold HF (1) · University of Aarhus (1) · University of Minnesota (1)
United States (8) · Norway (2) · Denmark (1) · South Korea (1) · Sweden (1)
Anders Nydahl, Phd (1) · Daniel Horwitz, MD (1) · Dean G Lorich, MD (1) · Espen Lindholm, MD (1) · Jason Habeck (1) · John Steinberg, DPM (1) · Mathias Kotyra, Md (1) · Nayana Nagaraj, MD, PhD, MPH (1) · Philipp Leucht, MD (1) · Seong-Hyop Kim, Professor (1) · Seroos Salavati, MD (1) · Thomas F. Bendtsen, MD, Ph.d. (1)