225 completed, 99 unknown, 40 recruiting, 25 terminated. 427 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 427 | Completed 225, Unknown 99, Recruiting 40, Terminated 25, Not yet recruiting 15, Withdrawn 13, Active not recruiting 10 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Capital Offload-Shock Immediate renal replacement therapy - Hypervolemia, Cardiogenic Shock | Phase 4 | Not yet recruiting | Ottawa Heart Institute Research Corporation | 456 | 2026-12-01 | 2026-10-30 |
| Roxadustat and Myocardial Injury After Off-Pump Coronary Artery Bypass Surgery Roxadustat, Placebo - Coronary Artery Disease, Coronary Artery Bypass Grafting | Phase 4 | Not yet recruiting | Peking University First Hospital | 80 | 2026-11-01 | 2026-11-03 |
| Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening Ischemia Lower-Extremity Revascularization, Donaperminogene Seltoplasmid - Chronic Limb-Threatening Ischemia, Diabetic Foot Ulcer | Phase 4 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 180 | 2026-10-20 | 2026-09-18 |
| DAN-RELEASE - Reconsidering Long-Term Aspirin in the Elderly Patients With Stable Ischemic Heart Disease Continuation of daily low-dose Aspirin, Discontinuation of daily low-dose Aspirin - Ischemic Heart Disease, Ischemic Heart Disease Chronic | Phase 4 | Recruiting | Odense University Hospital | 7000 | 2026-09-30 | 2026-10-05 |
| IMPROVE-STEMI: pPCI Plus Low-dose r-SK in STEMI Recombinant Streptokinase - ST Elevation Myocardial Infarction (STEMI) | Phase 4 | Not yet recruiting | The Affiliated Hospital of Xuzhou Medical University | 3300 | 2026-09-28 | 2026-10-15 |
| NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke MLC901, Standard treatment for acute ischemic stroke - Stroke, Stroke, Acute Ischemic | Phase 4 | Recruiting | EVD Pharmacy and Medical Company Limited | 80 | 2026-09-10 | 2026-10-20 |
| Dual Antiplatelet Therapy Strategies After Acute Myocardial Infarction Undergoing PCI: Prasugrel vs Ticagrelor & 12 Months vs 1-3 Months Prasugrel, Ticagrelor - Myocardial Infarction (MI) | Phase 4 | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 8100 | 2026-09-02 | 2026-09-09 |
| Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary Syndrome bempedoic acid, Ezetimibe, High-Intensity Statin Therapy - Acute Coronary Syndromes, Dyslipidemia | Phase 4 | Recruiting | Taipei Medical University Hospital | 400 | 2026-08-26 | 2026-09-17 |
| Intranasal Dexmedetomidine and Perioperative Myocardial Injury Intranasal Dexmedetomidine, Normal saline - Coronary Heart Disease, Myocardial Injury | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 140 | 2026-08-01 | 2026-07-30 |
| BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis Apixaban, Clopidogrel - Stroke, Ischemic | Phase 4 | Recruiting | Yonsei University | 586 | 2026-07-14 | 2026-10-16 |
| Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy - Acute Coronary Syndromes, STEMI | Phase 4 | Not yet recruiting | Gyeongsang National University Hospital | 1900 | 2026-07-01 | 2026-07-06 |
| Reperfusion Approach in Predicted In-hospital Delay for Primary PCI in STEMI Single, weight-adjusted i.v. bolus of tenecteplase, catheterisation - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Not yet recruiting | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | 240 | 2026-05-20 | 2026-06-11 |
| Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC） Aspirin (Early, 2h), Aspirin (Standard, 24h) - Cerebral Infarction, Thrombolysis | Phase 4 | Not yet recruiting | Beijing Chao Yang Hospital | 210 | 2026-05-01 | 2026-05-08 |
| Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia Recombinant Herpes Zoster Vaccine (Shingrix) - Cardiovascular Disease, Dementia | Phase 4 | Active not recruiting | Tor Biering-Sørensen | 168460 | 2026-04-28 | 2026-10-14 |
| Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure Ketone Monoester (KE) - Acute Heart Failure (AHF), Cardiogenic Shock | Phase 4 | Recruiting | Institute for Clinical and Experimental Medicine | 12 | 2026-04-04 | 2026-04-14 |
| Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary Syndrome Ferric Carboxymaltose Injection [Ferinject] - Acute Coronary Syndromes (ACS), Iron Deficiencies | Phase 4 | Recruiting | Fundación para la Investigación del Hospital Clínico de Valencia | 538 | 2026-03-05 | 2026-03-24 |
| Effects of Nicorandil on Microvascular Dysfunction in Patients With STEMI Undergoing Primary PCI nicorandil, Saline (NaCl 0,9 %) (placebo) - STEMI - ST-segment Elevation Myocardial Infarction | Phase 4 | Not yet recruiting | China National Center for Cardiovascular Diseases | 170 | 2026-03-01 | 2026-03-12 |
| Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia Aspirin 100 mg, Clopidogrel 75 mg, Rivaroxaban 15 mg - Coronary Artery Ectasia, Acute Coronary Syndromes (ACS) | Phase 4 | Recruiting | Instituto Nacional de Cardiologia Ignacio Chavez | 326 | 2026-02-11 | 2026-04-09 |
| Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor Rifaximin - ACS - Acute Coronary Syndrome, Ticagrelor | Phase 4 | Not yet recruiting | Collegium Medicum w Bydgoszczy | 50 | 2026-01-01 | 2025-10-02 |
| Intensive Cholesterol-Lowering Within 24 Hours of PCI Perioperative Period Recaticimab - STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI) | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Nanchang University | 2442 | 2026-01-01 | 2025-12-18 |
Showing 20 of 427. Sign in to see all of them.
Myocardial Infarction (214) · ST Elevation Myocardial Infarction (114) · Non-ST Elevated Myocardial Infarction (42) · Acute Coronary Syndrome (40) · Stroke (39) · Coronary Artery Disease (38) · Angina, Unstable (27) · Cardiovascular Diseases (27) · Cerebral Infarction (27) · Shock, Cardiogenic (23) · Chronic Limb-Threatening Ischemia (20) · Myocardial Ischemia (14) · Coronary Disease (13) · Thrombosis (13)
Pathologic Processes (427) · Pathological Conditions, Signs and Symptoms (427) · Vascular Diseases (403) · Cardiovascular Diseases (390) · Necrosis (377) · Infarction (370) · Heart Diseases (348) · Myocardial Ischemia (337) · Myocardial Infarction (128) · Nervous System Diseases (67) · Arteriosclerosis (66) · Brain Diseases (66) · Arterial Occlusive Diseases (65) · Central Nervous System Diseases (65)
Clopidogrel (49) · Ticagrelor (42) · Aspirin (36) · Prasugrel Hydrochloride (19) · Abciximab (16) · Atorvastatin (14) · Heparin (13) · Saline Solution (13) · Percutaneous Coronary Intervention (12) · Rosuvastatin Calcium (11) · Sodium Chloride (11) · Tirofiban (11) · Cilostazol (10) · Rivaroxaban (10) · bivalirudin (9)
Deutsches Herzzentrum Muenchen (7) · RenJi Hospital (6) · Assistance Publique - Hôpitaux de Paris (5) · Beijing Anzhen Hospital (5) · Samsung Medical Center (5) · Yonsei University (5) · Gyeongsang National University Hospital (4) · National Institute of Cardiovascular Diseases, Pakistan (4) · Ottawa Heart Institute Research Corporation (4) · Second Affiliated Hospital, Zhejiang University, School of Medicine (4) · St. Antonius Hospital (4) · University of Florida (4) · University of Leipzig (4) · University of Patras (4) · Xijing Hospital (4)
China (66) · Italy (43) · United States (43) · South Korea (34) · Canada (29) · Germany (29) · Netherlands (25) · France (19) · Poland (19) · Spain (19) · United Kingdom (18) · Sweden (16) · Brazil (15) · Czechia (14) · Denmark (14)
Adnan Kastrati, MD (6) · David Antoniucci, MD (4) · Dimitrios Alexopoulos, MD (3) · Holger Thiele, MD (3) · Marc Bosiers, MD (3) · Olivier F Bertrand, MD, PhD (3) · Albert Schoemig, MD (2) · Albert Schomig, MD (2) · Andrei C Sposito, MD, PhD (2) · Ben He, MD,PhD (2) · Borja Ibanez, MD PhD (2) · Colin Berry, MD PhD (2) · Dominick J Angiolillo, MD, PhD (2) · Dongdong Sun, M.D.,Ph.D. (2) · Francisco Fernandez-Aviles, MD, PhD (2)
PMID 36526898, PMID 17964349, PMID 19264239, PMID 23500251, PMID 25175921, PMID 28286967, PMID 28527771, PMID 33647946, PMID 34785173, PMID 35224730, PMID 36073634, PMID 40888716, PMID 41616808, PMID 41934630, PMID 10080465, PMID 10595951, PMID 11277825, PMID 11693742, PMID 11965271, PMID 12607706, PMID 12893742, PMID 15007110, PMID 15247962, PMID 15367828, PMID 15745837, PMID 15791442, PMID 15837243, PMID 15956631, PMID 16116055, PMID 16163360, PMID 1627164, PMID 16271642, PMID 16271643, PMID 16275864, PMID 16286167, PMID 16386660, PMID 16488800, PMID 16507801, PMID 16531613, PMID 17105848, PMID 17145253, PMID 17145988, PMID 17261652, PMID 17394957, PMID 17398308, PMID 17467513, PMID 17470822, PMID 17478142, PMID 17498576, PMID 17697815
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