422 completed, 272 unknown, 104 recruiting, 59 not yet recruiting. 365 Not applicable, 164 Phase 2, 94 Phase 3, 68 Phase 1, 17 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Identifying the Best Follow up Approach for People Who Have Had Treatment to Cure Newly Diagnosed Prostate Cancer Hospital based follow up, Primary care based follow up, Planned shared care follow up - Prostate Cancer | Not yet recruiting | Imperial College London | 100000 | 2026-12-01 | 2026-10-06 | |
| A Prospective Study to Evaluate the Diagnostic Accuracy of Computer-aided Diagnosis (CADx) System in Real-time Characterization of Colorectal Neoplasia CADx - Colorectal Neoplasms | Not yet recruiting | Chinese University of Hong Kong | 510 | 2026-12-01 | 2026-09-22 | |
| Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic Stenosis Dapagliflozin (DAPA), Spironolactone (drug), Spironolactone + Dapagliflozin - Aortic Stenosis | Phase 2 | Not yet recruiting | University College, London | 445 | 2026-12-01 | 2026-09-11 |
| An Adaptive Platform Trial for Evaluation of Novel Treatment Regimens in Children and Adolescents With HIV in Africa Dolutegravir (DTG), Abacavir (ABC), Lamivudine (3TC) - HIV Infection | Phase 3 | Not yet recruiting | University College, London | 800 | 2026-11-01 | 2026-08-28 |
| ImprovINg the TIMEly Diagnosis and Treatment of Cancer and Cardio-metabolic Diseases in People With Mental Disorders: Reducing Health Disparities Through Integrated Care Not applicable - observational study - Mental Health, Cancer | Not yet recruiting | IRCCS San Raffaele | 120 | 2026-11-01 | 2026-09-28 | |
| Imaging and Predictive Modelling of Proliferative Vitreoretinopathy. Proliferative Vitreoretinopathy | Enrolling by invitation | University College, London | 100 | 2026-10-12 | 2026-07-02 | |
| Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study Cryotherapy - ME/CFS, Fibromyalgia (FM) | Not applicable | Not yet recruiting | Oxford Brookes University | 40 | 2026-10-01 | 2026-10-14 |
| Prostate MRI Analysis by Radiologists and Artificial Intelligence - Disease Identification and Guided Management AI (Lucida Pi) interpretation, Radiologist interpretation - Prostate CA | Not applicable | Not yet recruiting | University College, London | 500 | 2026-10-01 | 2026-06-30 |
| A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device. Standard of Care (Investigator Choice), DIALIVE 2.0 liver dialysis Device plus available Standard of Care - Acute-on-Chronic Liver Failure (ACLF), Liver Cirrhosis | Not applicable | Recruiting | Yaqrit Ltd | 72 | 2026-10-01 | 2026-09-22 |
| PeriOperative Medicine - Metabolic Inflexibility as a Mechanism for Myocardial Injury After Non-Cardiac Surgery Pre-operative Metabolic Inflexibility - MINS | Not yet recruiting | University College, London | 300 | 2026-10-01 | 2026-07-14 | |
| PRESTO: A Phase III Randomised Controlled Trial of Dose-escalated Proton Beam Therapy Versus Standard of Care Radiotherapy for Functioning Pituitary Tumours Standard dose Intensity-Modulated Radiation Therapy (IMRT), Standard dose Proton Beam Therapy (PBT), Escalated dose Proton Beam Therapy (PBT) - Acromegaly Due to Pituitary Adenoma, Cushing's Disease | Phase 3 | Not yet recruiting | University College, London | 82 | 2026-09-01 | 2026-10-01 |
| Advanced Diffusion Magnetic reSonance Prostate Imaging for Reducing Extraneous Biopsies (ASPIRE) - Calibration Component (Multi-centre Scanner Calibration) and Validation Component (Multi-centre Validation) MRI - Prostate Cancer (Diagnosis) | Not applicable | Not yet recruiting | University College, London | 660 | 2026-09-01 | 2026-09-09 |
| Building a Computational Model of Auditory Hallucinations Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature | Not yet recruiting | King's College London | 146 | 2026-09-01 | 2026-09-15 | |
| Potential for Recovery of Voluntary Finger Extension After Stroke Neuromuscular Electrical Stimulation and Home Exercise Programme - Stroke | Not applicable | Not yet recruiting | University College, London | 100 | 2026-09-01 | 2026-05-18 |
| Intensive Comprehensive Aphasia Programme for People With Post-Stroke Aphasia ICAP, Standard Care (in control arm) - Aphasia Following Cerebral Infarction | Not applicable | Not yet recruiting | University College, London | 334 | 2026-09-01 | 2026-04-13 |
| Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer Abiraterone, Apalutamide, Enzalutamide or Darolutamide (ARPI therapy) (per standard of care) therapy - Prostate Cancer, mHSPC | Phase 3 | Recruiting | University College, London | 1500 | 2026-08-28 | 2026-10-16 |
| The Feasibility of Electrical Impedance Tomography to Guide Non-invasive Respiratory Interventions in Chronic Respiratory Disease electrical impedance tomography - COPD, Non Invasive Ventilation (NIV) | Enrolling by invitation | Royal Free Hospital NHS Foundation Trust | 20 | 2026-08-27 | 2026-09-09 | |
| Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA) CT-Guided Intra-Operative Middle Meningeal Artery Interruption - Chronic Subdural Hematomas | Not applicable | Recruiting | University College, London | 30 | 2026-08-01 | 2026-08-04 |
| Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South Africa CPOL group training - HIV, Sexually Transmitted Infections (STI) | Not applicable | Not yet recruiting | Africa Health Research Institute | 60 | 2026-08-01 | 2026-08-03 |
| Respiratory OBservation Using Ultra-Sensitive nanoTechnology Nanotechnology respiratory monitor - Respiratory Monitoring | Not applicable | Not yet recruiting | University College, London | 148 | 2026-08-01 | 2026-06-16 |
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Prostatic Neoplasms (37) · Stroke (32) · Dementia (28) · Heart Failure (27) · COVID-19 (23) · Myocardial Infarction (23) · Pulmonary Disease, Chronic Obstructive (20) · Cardiovascular Diseases (18) · Parkinson Disease (18) · Anxiety Disorders (17) · Depression (17) · Lymphoma (16) · Obesity (15) · Angina, Stable (14) · Lung Neoplasms (14)
Rituximab (12) · Standard of Care (12) · Cisplatin (11) · Cyclophosphamide (11) · Radiotherapy (11) · pembrolizumab (11) · Gemcitabine (7) · Moxifloxacin (7) · Blood Specimen Collection (6) · Etoposide (6) · Rifampin (6) · Transcranial Direct Current Stimulation (6) · Carboplatin (5) · Cognitive Behavioral Therapy (5) · Deep Brain Stimulation (5)
United Kingdom (748) · Germany (33) · Italy (31) · United States (28) · France (25) · South Africa (24) · Spain (22) · Netherlands (21) · Switzerland (20) · Canada (19) · Uganda (16) · Belgium (15) · Denmark (13) · Kenya (13) · Portugal (13)
Harry Hemingway, FRCP (12) · Doris-Eva Bamiou, PhD (4) · Fares S Haddad (4) · Rachel L Batterham, PhD FRCP (4) · Aimee Spector (3) · Alexander P Leff, Professor (3) · D O'Neill, PhD (3) · Emily Herrett, MSc (3) · Graham Collins (3) · John R Hurst, PhD FRCP (3) · Karl Peggs (3) · Shonit Punwani (3) · Siow M. Lee, MD, PhD, FRCP (3) · Stuart Taylor (3)
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2014 (9), 2009 (8), 2005 (5), 2018 (4), 2015 (3), 2017 (3), 2004 (2), 2019 (2), 2023 (2), U01AI150510 (2), 2008 (1), 2016 (1), 3OT2OD026545 (1), P30CA008748 (1), R01AI051355 (1)