12 completed, 3 recruiting, 3 terminated, 2 unknown. 9 Not applicable, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 6, Unknown 2, Terminated 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow Hypotension and Shock: new trials by email Literature Review of Hypotension and Shock trials Research Report on Hypotension and Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE) Dopamine administration, Norepinephrine - Hypotension and Shock, Pulmonary Hypertension of the Newborn (PPHN) | Phase 4 | Recruiting | University of California, Davis | 30 | 2026-10-30 | 2026-08-18 |
| Role of Inferior Vena Cava Dispensability Index in Predicting Hypotension of Cement Syndrome in Hip Replacement Surgery Under General Anaesthesia Ultrasound measurement of IVC - Cement Syndrome, Hypotension and Shock | Active not recruiting | Ain Shams University | 30 | 2025-12-20 | 2026-06-25 | |
| Pleth Variability Index for Predicting Low Blood Pressure During Maintenance Hemodialysis Non-invasive Monitoring - Hypotension and Shock, Hemodialysis | Recruiting | First Affiliated Hospital of Wannan Medical College | 200 | 2025-02-01 | 2025-06-15 | |
| Early Initiated Vasopressor Therapy in the Emergency Department Noradrenaline - Shock, Shock, Septic | Phase 3 | Recruiting | Odense University Hospital | 320 | 2023-12-08 | 2025-07-01 |
| Norepinephrine Administration Through a Midline Catheter in an Intermediate Care Unit Norepinephrine - Septic Shock, Norepinephrine Adverse Reaction | Completed | Region Skane | 473 | 2023-10-03 | 2024-03-12 | |
| Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure Norepinephrine, Lactated Ringers, Intravenous, normal saline - Respiratory Failure, Hypotension and Shock | Phase 3 | Completed | Wright State University | 42 | 2022-08-09 | 2024-07-15 |
| BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study LUCAS 2 Active Decompression 2, Hypotension, Intensive care transport - Cardiac Arrest, Out-Of-Hospital, Hypotension and Shock | Not applicable | Completed | Oslo University Hospital | 183 | 2021-05-18 | 2024-04-03 |
| Physiological Validation of Current Machine Learning Models for Hemodynamic Instability in Humans Assigned Interventions - Hypotension and Shock | Not applicable | Completed | Mayo Clinic | 100 | 2021-05-12 | 2023-05-31 |
| Prehospital Management of Hypotensive Trauma in HEMS Hypotension and Shock, Wounds and Injuries | Completed | Azienda Usl di Bologna | 1268 | 2021-05-01 | 2026-10-08 | |
| BP Management System User Acceptance Testing VIGORIS Blood Pressure Management Clinical Decision Support System - Hypotension and Shock | Not applicable | Completed | Andrew Tomas Reisner | 20 | 2021-01-21 | 2025-01-27 |
| Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant Recipients Angiotensin II - Shock, Surgical, Shock | Phase 4 | Completed | University of Illinois at Chicago | 20 | 2020-08-13 | 2022-12-21 |
| Accuracy of Non-Invasive Blood Pressure Measurements at the Arm, Calf , and Finger Combined non-invasive intermittent (oscillometric arm cuff), non-invasive continuous (finger cuff and ClearSight device), and invasive continuous (intra-arterial catheter) BP measurements - Hypotension and Shock, Hypertension | Not applicable | Completed | Centre Hospitalier Régional d'Orléans | 133 | 2020-02-22 | 2021-07-01 |
| Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates Multimodal objective non-invasive Monitoring - Hypotension and Shock, Hypoperfusion | Terminated | University College Cork | 56 | 2019-11-09 | 2023-01-27 | |
| The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams ultrasound protocol - Dyspnea, Coma | Not applicable | Terminated | Rijnstate Hospital | 100 | 2019-01-18 | 2020-07-20 |
| Measurement of Hemodynamic Responses to Lower Body Negative Pressure Lower body negative pressure - Hypotension and Shock | Not applicable | Completed | Mayo Clinic | 24 | 2019-01-08 | 2019-06-12 |
| Role of Low Dose Epinephrine Boluses In Acute Hypotension Epinephrine, Traditional management of shock - Hypotension and Shock | Not applicable | Unknown | Assiut University | 50 | 2019-01-01 | 2018-09-14 |
| Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status Peripheral Intravenous Analysis (PIVA), Standard of care invasive vascular monitoring, Standard noninvasive vascular monitoring - Systemic Inflammatory Response Syndrome, Distributive Shock | Terminated | Vanderbilt University Medical Center | 180 | 2018-01-08 | 2021-04-12 | |
| ClearSight Validation in Pediatrics Measurement by Clearsight device - Shock, Hypotension and Shock | Completed | Nemours Children's Clinic | 10 | 2017-11-02 | 2023-06-23 | |
| A Comparison of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation Isotonic crystalloid solution resuscitation, Colloid solution resuscitation - Hypotension and Shock | Not applicable | Unknown | Mahidol University | 320 | 2014-09-01 | 2016-05-25 |
| Predict Fluid Responsiveness in Spinal Anesthesia Trans-thoracic echocardiography, Passive Leg Raising Test - Hypotension and Shock, Excessive Amount of Blood / Fluid Infusion | Not applicable | Completed | Ente Ospedaliero Cantonale, Bellinzona | 429 | 2014-05-01 | 2020-07-13 |
Showing 20 of 21. Sign in to see all of them.
Hypotension (21) · Shock (21) · Emergencies (2) · Respiratory Insufficiency (2) · Shock, Septic (2) · Atrial Fibrillation (1) · Brain Injuries, Traumatic (1) · Coma (1) · Dyspnea (1) · Hypertension (1) · Hypertension, Pulmonary (1) · Hypovolemia (1) · Kidney Failure, Chronic (1) · Out-of-Hospital Cardiac Arrest (1) · Shock, Hemorrhagic (1)
Cardiovascular Diseases (21) · Pathologic Processes (21) · Pathological Conditions, Signs and Symptoms (21) · Vascular Diseases (21) · Disease Attributes (3) · Inflammation (3) · Respiration Disorders (3) · Respiratory Tract Diseases (3) · Heart Diseases (2) · Infections (2) · Nervous System Diseases (2) · Sepsis (2) · Systemic Inflammatory Response Syndrome (2) · Arrhythmias, Cardiac (1) · Brain Diseases (1)
Norepinephrine (5) · Lower Body Negative Pressure (2) · Angiotensin II (1) · Colloids (1) · Crystalloid Solutions (1) · Epinephrine (1) · Hypotension, Controlled (1) · Plasma-lyte 148 (1) · Plasmalyte A (1) · Ringer's Lactate (1) · Saline Solution (1) · Vasoconstrictor Agents (1)
Mayo Clinic (2) · Ain Shams University (1) · Andrew Tomas Reisner (1) · Assiut University (1) · Azienda Usl di Bologna (1) · Centre Hospitalier Régional d'Orléans (1) · Ente Ospedaliero Cantonale, Bellinzona (1) · First Affiliated Hospital of Wannan Medical College (1) · Mahidol University (1) · Nemours Children's Clinic (1) · Odense University Hospital (1) · Oslo University Hospital (1) · Region Skane (1) · Rijnstate Hospital (1) · University College Cork (1)
United States (8) · Sweden (2) · China (1) · Denmark (1) · Egypt (1) · France (1) · Ireland (1) · Italy (1) · Netherlands (1) · Norway (1) · Switzerland (1) · Thailand (1)
Timothy B Curry (2) · Andrea Saporito, MD (1) · Andrew T Reisner, MD (1) · Aya Ali Mahmoud Bayoumy, Lecturer Phd (1) · Chairat Permpikul, MD. (1) · Deepika Sankaran, MD (1) · Eugene M Dempsey, MD (1) · Gustav Torisson, PhD (1) · Justin E Richards, MD (1) · Kelly L. Kohorst, MD (1) · Lars Wik, MD, PhD (1) · Lasse P Bentsen, MD (1) · Matthew Koroscil, MD (1)
PMID 25782753, PMID 26825635, PMID 27050884, PMID 29319635, PMID 29736468, PMID 29793591, PMID 30741331, PMID 30917843, PMID 31461138, PMID 34089087, PMID 37232853, PMID 38048986, PMID 39806688
2023 (1)