39 completed, 8 unknown, 6 recruiting, 2 not yet recruiting. 32 Not applicable, 7 Phase 4, 5 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow Crystalloid Solutions: new trials by email Literature Review of Crystalloid Solutions trials Research Report on Crystalloid Solutions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of hBMMSC Injection in Patients With aPAP The human Bone Marrow Mesenchymal Stem Cell (hBMMSC) injection, Lactated Ringer's Injection (crystalloid) - Autoimmune Pulmonary Alveolar Proteinosis | Phase 2 | Not yet recruiting | Jiuzhitang Maker (Beijing) Cell Technology Co.,Ltd. | 70 | 2026-10-30 | 2026-10-22 |
| Hydroxyethyl Starch Versus Crystalloid and Postoperative Major Adverse Kidney Complications Volulyte® (6% HES 130/0.4 in balanced solution), Crystalloid solutions - Cardiac Surgery | Phase 4 | Recruiting | Seoul National University Hospital | 1292 | 2026-06-22 | 2026-07-30 |
| Minimal Flow Anesthesia and Infection Risk Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG - Minimal Flow Anesthesia, General Anaesthesia | Not applicable | Completed | Ankara City Hospital Bilkent | 140 | 2025-08-01 | 2026-10-05 |
| Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff - Pre-Eclampsia | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 62 | 2025-07-01 | 2024-12-06 |
| Assessment of Venous Return During Volume Expansion: a Prospective Observational Study Fluid challenge of 500ml of crystalloid - Hemodynamic Changes | Recruiting | Università Politecnica delle Marche | 45 | 2025-03-01 | 2026-03-30 | |
| The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery Albumin solution, Crystalloid solutions - Acute Kidney Injury, Pediatric Cardiac Surgery | Not applicable | Recruiting | Seoul National University Hospital | 190 | 2025-01-09 | 2025-04-23 |
| Initial Resuscitation for Acute Kidney Injury in Cirrhosis Recommendation: No Further Resuscitation, Recommendation: Resuscitation with Crystalloid, Recommendation: Resuscitation with Colloid - Cirrhosis, Liver, Acute Kidney Injury | Not applicable | Recruiting | Massachusetts General Hospital | 50 | 2024-09-12 | 2026-03-13 |
| Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock Crystalloid and blood as resuscitation, crystalloid, blood and low dose of norepinephrine - Mortality Rate, Hemorrhagic Shock | Not applicable | Completed | Tanta University | 60 | 2024-08-30 | 2025-07-11 |
| Volume Kinetics of Fluid Resuscitation in Early Sepsis Ringer's Lactate - Fluid and Electrolyte Imbalance | Completed | Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu | 13 | 2024-06-19 | 2026-10-20 | |
| Effect of Early Administration of Albumin 20% Versus Crystalloid Albumin Human - Septic Shock | Not applicable | Unknown | Egymedicalpedia | 46 | 2024-06-01 | 2024-06-06 |
| Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine Crystalloid - 0 ml/kg, Crystalloid - 5 ml/kg, Crystalloid - 10 ml/kg - Adverse Effect | Not applicable | Completed | General Hospital of Ningxia Medical University | 90 | 2023-03-21 | 2023-06-22 |
| Comparison of Hydroxyethyl Starch and Crystalloid Coload Combined With Norepinephrine Infusion for Hypotension Hydroxyethyl starch, Crystalloid - Adverse Effect | Not applicable | Completed | General Hospital of Ningxia Medical University | 80 | 2023-01-11 | 2023-03-22 |
| The Impact of Intra-operative Fluid Infusion Rate on Microcirculation Crystalloid Solutions - Fluid Therapy, Microcirculation | Not applicable | Recruiting | University Hospital Hradec Kralove | 80 | 2022-10-01 | 2025-03-27 |
| Plasma Resuscitation Without Lung Injury Pathogen-Reduced Plasma, Crystalloid Solutions - Burns | Phase 4 | Terminated | Coalition for National Trauma Research | 13 | 2022-08-17 | 2025-01-29 |
| International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy - Liver Cirrhosis, Acute Kidney Injury | Completed | Azienda Ospedaliera di Padova | 1456 | 2022-07-01 | 2024-01-30 | |
| Albumin and Crystalloid Administration in Septic Shock Treatment, Placebo - Septic Shock | Phase 4 | Recruiting | Asan Medical Center | 2426 | 2022-01-17 | 2026-07-16 |
| Pre-op Fluid Study Crystalloid Solutions - Hypotension Drug-Induced, Anesthesia | Not applicable | Active not recruiting | Medical University of Graz | 550 | 2021-11-01 | 2025-11-21 |
| Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock 20% Albumin, Crystalloid - Sepsis, Severe, Sepsis | Not applicable | Completed | Rachael Cusack | 100 | 2021-09-01 | 2024-10-26 |
| Compare Between the Effect of Topical Tranexamic Acid Versus Hydrogen Peroxide on Blood Loss in Spine Surgeries Topical Solution, Topical Foam, Topical - Blood Loss | Phase 3 | Unknown | Minia University | 120 | 2021-06-01 | 2021-12-09 |
| The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension Crystalloid, noradrenaline - Norepinephrine, Sepsis | Not applicable | Completed | Tanta University | 64 | 2021-05-01 | 2023-03-24 |
Showing 20 of 58. Sign in to see all of them.
Sepsis (8) · Shock, Septic (7) · Acute Kidney Injury (6) · Hypotension (5) · Postoperative Complications (4) · Edema (3) · Hemorrhage (3) · Liver Cirrhosis (3) · Shock (3) · Critical Illness (2) · Fibrosis (2) · Hepatorenal Syndrome (2) · Acid-Base Imbalance (1) · Acute Lung Injury (1) · Acute-On-Chronic Liver Failure (1)
General Hospital of Ningxia Medical University (4) · Seoul National University Hospital (4) · Asan Medical Center (2) · Istanbul University (2) · Mahidol University (2) · Tanta University (2) · University Hospital Schleswig-Holstein (2) · Alaa Mazy (1) · Ankara City Hospital Bilkent (1) · Assiut University (1) · Ataturk Training and Research Hospital (1) · Azienda Ospedaliera di Padova (1) · Baylor College of Medicine (1) · Bozyaka Training and Research Hospital (1) · Cairo University (1)
United States (9) · Egypt (8) · China (7) · South Korea (7) · Germany (4) · Italy (4) · Turkey (Türkiye) (4) · Austria (3) · Canada (3) · France (3) · United Kingdom (3) · Belgium (2) · India (2) · Thailand (2) · Argentina (1)
Xinli Ni, Dr. (2) · Yi Chen, M.D. (2) · Adam Rahman, MD, FRCPC (1) · Amani Khairy, Professor (1) · Amy Lee, MD (1) · Andrea Kurz, MD (1) · Andrea Kurz, Prof (1) · Antonio Pesenti, MD (1) · Chairat Permpikul, MD. (1) · Charles Phillips, M.D. (1) · Claudia Wei, MD (1) · Daniel De Backer, MD,PhD (1) · David D. Rose, PhD (1) · Demet Altun Bingol, Assoc. Prof. (1)
PMID 15758080, PMID 16879732, PMID 20725823, PMID 22580944, PMID 24108515, PMID 24635772, PMID 25638527, PMID 25887027, PMID 26152341, PMID 26162676, PMID 26181335, PMID 26475802, PMID 26741579, PMID 26825952, PMID 26847922, PMID 28411114, PMID 28903154, PMID 28973220, PMID 28988172, PMID 29150842, PMID 29787743, PMID 30261898, PMID 32409206, PMID 32585739, PMID 32753064, PMID 33741039, PMID 34825972, PMID 35842352, PMID 36495775, PMID 36657900, PMID 37721127, PMID 37857068, PMID 39516883, PMID 40020556, PMID 40058397, PMID 40725675, PMID 41892832
2009 (1), K23DK128567 (1)