115 completed, 38 unknown, 27 recruiting, 10 active not recruiting. 90 Not applicable, 20 Phase 4, 13 Phase 3, 10 Phase 2, 3 Phase 1.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Pre Hospital Triage of Patients at Intermediate and High Risk for ACS Integrating the HEAR score and hs POC troponin into pre hospital triage decision-making: - Non ST Segment Elevation Acute Coronary Syndrome | Not applicable | Recruiting | Cyril Camaro | 1048 | 2026-09-04 | 2026-09-10 |
| Individual Patient Data Meta-Analysis of Prospective Studies of Patients Treated With the GORE® Iliac Branched Endoprosthesis Iliac Branched Endoprosthesis - Aneurysm | Recruiting | Rijnstate Hospital | 1200 | 2026-07-31 | 2026-07-15 | |
| CRYO-1: Cryoablation in Elderly Patients With Early-Stage Breast Cancer. Cryoablation / Cryotherapy - Breast Cancer Stage I, Breast Cancer Early Stage Breast Cancer (Stage 1-3) | Not applicable | Not yet recruiting | St. Antonius Hospital | 61 | 2026-04-01 | 2026-03-23 |
| Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation IMPROVE Risk Model - Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction | Not applicable | Recruiting | Maastricht University Medical Center | 613 | 2026-03-31 | 2026-05-15 |
| Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure Stent placement - Aorto Iliac Occlusive Disease, Blood Pressure | Not applicable | Recruiting | Rijnstate Hospital | 20 | 2026-03-30 | 2026-04-03 |
| Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain | Recruiting | Rijnstate Hospital | 20 | 2025-12-01 | 2025-12-26 | |
| Triaxial Accelerometry Study Total Hip Arthroplasty (THA), Accelerometers | Completed | Rijnstate Hospital | 32 | 2025-11-22 | 2026-06-23 | |
| Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical Implementation ENDORISK personalized risk assesment for lymph node metastases in endometrial cancer. - Endometrial Cancer | Not applicable | Recruiting | Radboud University Medical Center | 735 | 2025-10-23 | 2026-07-29 |
| Blood Flow Evaluation After Carotid Surgical Treatment Ultrasound-based flow imaging - Carotid Endarterectomy | Not yet recruiting | Rijnstate Hospital | 40 | 2025-09-01 | 2025-08-05 | |
| Monitoring Nutritional Consequences of Obesity Treatment on Women's Health Obesity and Obesity-related Medical Conditions, Bariatric Surgery | Recruiting | Wageningen University and Research | 1150 | 2025-01-28 | 2025-07-10 | |
| Flexion-Extension Radiograph Imaging Protocol Reliability Study Flexion-extension radiographs - Lumbar Spinal Stenosis, Spinal Instability | Completed | Rijnstate Hospital | 50 | 2024-11-27 | 2026-08-12 | |
| Placebo Effect In Spinal Cord Electrical Stimulation for Pain Spinal cord stimulation - Chronic Postoperative Pain | Not applicable | Recruiting | Sahlgrenska University Hospital | 50 | 2024-11-15 | 2025-12-02 |
| Supplemental Screening for Women With Extremely Dense Breast Tissue: the DENSE-2 Trial Contrast-enhanced mammography (CEM), Abbreviated MRI (AB-MRI) - Breast Cancer | Not applicable | Recruiting | C.H. van Gils | 36000 | 2024-11-11 | 2026-05-11 |
| The Effect of a 2-week Preoperative Vegan Diet Versus Omnivorous Diet on the Protein Turnover in the Osteoarthritic Knee Vegan diet, Omnivorous diet - Osteo Arthritis Knee, Protein Synthesis | Not applicable | Recruiting | Wageningen University | 40 | 2024-10-22 | 2025-04-01 |
| Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial Remimazolam, Midazolam - Sedation for Diagnostic Gastroscopy | Phase 4 | Recruiting | Koen Munters | 148 | 2024-10-21 | 2024-12-04 |
| Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life Protein-enriched diet, Progressive resistance exercise - Hip Fractures | Not applicable | Recruiting | Wageningen University | 102 | 2024-09-01 | 2026-08-18 |
| DUTCH Weight Control in Atrial Fibrillation Study Semaglutide 3.2 MG/ML, Placebo - Atrial Fibrillation, Obesity | Phase 4 | Active not recruiting | Rijnstate Hospital | 280 | 2024-07-21 | 2026-10-01 |
| Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial Bariatric surgery strategy - Heart Failure with Preserved Ejection Fraction, Atrial Fibrillation | Not applicable | Recruiting | University Medical Center Groningen | 108 | 2024-07-01 | 2025-04-01 |
| Hip Socket Erosion Study Femoral Neck Fractures, Hemiarthroplasty | Completed | Rijnstate Hospital | 134 | 2024-06-19 | 2026-06-25 |
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Aortic Aneurysm, Abdominal (12) · Obesity (12) · Obesity, Morbid (11) · Inflammatory Bowel Diseases (5) · Motor Activity (5) · Pain (5) · Acquired Immunodeficiency Syndrome (4) · Breast Neoplasms (4) · Cardiovascular Diseases (4) · Carotid Stenosis (4) · Chronic Pain (4) · Dyspnea (4) · Heart Arrest (4) · Pulmonary Disease, Chronic Obstructive (4) · Sleep Apnea, Obstructive (4)
Blood Specimen Collection (3) · Spinal Cord Stimulation (3) · Standard of Care (3) · Surveys and Questionnaires (3) · ferrous fumarate (3) · Carboplatin (2) · Diazoxide (2) · Endovascular Aneurysm Repair (2) · Gastric Bypass (2) · Midazolam (2) · Pancreas, Artificial (2) · Radiofrequency Ablation (2) · Vascular Stiffness (2) · ferric carboxymaltose (2) · ferrous gluconate (2)
Netherlands (199) · Belgium (5) · Italy (5) · Germany (3) · New Zealand (3) · Spain (3) · Sweden (3) · Norway (2) · Switzerland (2) · United Kingdom (2) · Australia (1) · Denmark (1) · France (1) · Lithuania (1) · Mexico (1)
Michel Reijnen, MD, PhD (5) · F.J. Berends, MD, PhD (3) · Eric J Hazebroek, MD, PhD (2) · Hans de Boer, MD PhD (2) · Harry van Goor, MD, PhD (2) · Jacqueline E. Vernooij, MD, MA (2) · Jan Willem Kallewaard, MD (2) · Job LC van Susante, Dr. PhD. (2) · Mark V Koning, MD, PhD (2) · Michel Reijnen (2) · Michel Reijnen, MD, Prof (2) · Michel Reijnen, MD, prof (2) · A Jansen, Drs (1) · A W Nap, MSc, PhD (1)
PMID 12699951, PMID 17331245, PMID 19262961, PMID 19910177, PMID 21679070, PMID 21767371, PMID 21854655, PMID 21871072, PMID 22589500, PMID 22692651, PMID 23141679, PMID 23312507, PMID 24282511, PMID 24726004, PMID 25285269, PMID 25879884, PMID 25995238, PMID 26188742, PMID 26208341, PMID 26384469, PMID 26487748, PMID 26542508, PMID 26689767, PMID 26971488, PMID 27619827, PMID 29327182, PMID 29618011, PMID 29739430, PMID 29931179, PMID 29946174, PMID 30073496, PMID 30202851, PMID 31000063, PMID 31479209, PMID 31776782, PMID 32070400, PMID 32295455, PMID 32334703, PMID 32402684, PMID 32594305, PMID 33295981, PMID 33397767, PMID 33538699, PMID 33722066, PMID 33973866, PMID 33998271, PMID 34089087, PMID 34091818, PMID 34258321, PMID 34392637
2017 (1), 2023 (1), 2025 (1)