369 completed, 99 unknown, 68 recruiting, 40 terminated. 664 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 664 | Completed 369, Unknown 99, Recruiting 68, Terminated 40, Not yet recruiting 35, Active not recruiting 21, Withdrawn 19, Enrolling by invitation 9, Suspended 4 |
Follow Headache Disorders, Primary: new trials by email Literature Review of Headache Disorders, Primary trials Research Report on Headache Disorders, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EMBRACE Study: Enduring Migraine Benefit From Responsive Artery Coil Embolization TEMMA Endovascular Treatment - Migraine Disorders, Refractory Migraine | Not applicable | Withdrawn | Cortex Neurovascular | 2028-03-01 | 2026-10-27 | |
| Multimodal Therapy for Somatosensory Tinnitus Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support - Ear Noise, Tinnitus, Noise Induced | Not applicable | Not yet recruiting | Charles University, Czech Republic | 160 | 2027-01-01 | 2026-03-12 |
| A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant Migraine Neurostimulator - Resistant Migraine, Chronic Migraine Headache | Not applicable | Recruiting | Salvia BioElectronics | 150 | 2026-12-01 | 2026-08-28 |
| Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial Migraine Behavioral Treatment - Migraine, Headache | Not applicable | Not yet recruiting | Mayo Clinic | 24 | 2026-12-01 | 2026-06-16 |
| A Prospective Study of Rimegepant for Short-term Preventive Treatment of Night-shift-related Migraine in Healthcare Professionals Rimegepant 75 mg ODT, Standard Care - Migraine Disorders | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 260 | 2026-12-01 | 2026-11-05 |
| Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education - Migraine, Migraine in Adolescence | Not applicable | Recruiting | University of Colorado, Denver | 72 | 2026-11-10 | 2026-11-05 |
| Low-Intensity Focused Ultrasound Targeting the Dorsolateral Prefrontal Cortex for Preventive Treatment of Chronic Migraine Low-Intensity Focused Ultrasound Stimulation, Sham Low-Intensity Focused Ultrasound Stimulation - Chronic Migraine Headache | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 36 | 2026-10-08 | 2026-10-05 |
| Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in Youth Active Remote Electrical Neuromodulation, Sham Remote Electrical Neuromodulation - Migraine, Migraine Headache | Not applicable | Not yet recruiting | University of Calgary | 30 | 2026-10-01 | 2026-08-19 |
| Behavioral Resources and Awareness for Veterans With Episodic Migraine: Impact on Neurological Disability and Quality of Life- Pilot Cognitive behavioral therapy for migraine (CBTm), MEintervention - Migraine, Migraine Headache | Not applicable | Not yet recruiting | Yale University | 24 | 2026-10-01 | 2026-08-31 |
| Using Virtual Reality to Teach Mindfulness to People With Migraine ACT therapy delivered by REACT NeuroVR headset - Migraine Disorders, Migraine With Aura | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 160 | 2026-09-30 | 2026-09-30 |
| A Prospective Interventional Study of Intranasal Zavegepant for the Acute Treatment of Migraine Patient Headache Diary, Patient Reported Outcome, intranasal zavegepant - Migraine | Not applicable | Not yet recruiting | American Center for Psychiatry and Neurology | 250 | 2026-09-30 | 2026-10-06 |
| Marine Lipids Ease Painful TMD SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement - Temporomandibular Disorder (TMD) | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 100 | 2026-09-25 | 2026-11-05 |
| Suppressive Functions of Regulatory T Cells in Migraine Blood sampling, questionnaire and phone call - Chronic Migraine | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 24 | 2026-09-10 | 2026-10-14 |
| Vibratory Stimulation for the Treatment of Chronic Pain Vibrotactile Stimulation, Sham Stimulation - Chronic Pain, Pelvic Pain | Not applicable | Suspended | Stanford University | 50 | 2026-09-01 | 2026-04-24 |
| Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine Multi-Segmental Spinal Manual Therapy - Migraine Disorders | Not applicable | Not yet recruiting | Borna Farhoomand | 10 | 2026-09-01 | 2026-08-25 |
| Influence of Osteopathic Intervention on Cervical Muscles in Tension Headaches in Women Placebo Technique, Stretching technique, Inhibition of the suboccipital - Tension Headaches | Not applicable | Not yet recruiting | Escola Superior de Tecnologia da Saúde do Porto | 43 | 2026-09-01 | 2026-06-25 |
| The Effects of Physiotherapy in Migraine Physiotherapy program - Migraine | Not applicable | Recruiting | Ankara Yildirim Beyazıt University | 50 | 2026-08-10 | 2026-09-22 |
| Fire Needling Plus Filiform Needling for Chronic Migraine With Comorbid Tension-Type Headache filiform needling, fire needling combined with filiform needling - Chronic Migraine, Tension-type Headache | Not applicable | Not yet recruiting | Beijing Hospital of Traditional Chinese Medicine | 88 | 2026-08-01 | 2026-06-08 |
| A Comprehensive Digital Care Program for Migraine Management Neuromodulation Wearable Device, Migraine Digital Care Program - Migraine, Migraine With Aura | Not applicable | Enrolling by invitation | Hinge Health, Inc | 140 | 2026-07-09 | 2026-09-17 |
| Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study Foundational dietary supplement, Luteal phase dietary supplement add-on, Migraine phase dietary supplement add-on - Migraine, Migraine Disease | Not applicable | Not yet recruiting | Miracle Wellness LLC | 920 | 2026-07-08 | 2026-06-08 |
Showing 20 of 664. Sign in to see all of them.
Migraine Disorders (529) · Headache (126) · Tension-Type Headache (80) · Pain (57) · Migraine without Aura (51) · Cluster Headache (44) · Migraine with Aura (43) · Headache Disorders (31) · Chronic Pain (20) · Motor Activity (14) · Anxiety Disorders (11) · Depression (11) · Epilepsy (10) · Sleep Initiation and Maintenance Disorders (10)
Nervous System Diseases (662) · Central Nervous System Diseases (660) · Brain Diseases (659) · Headache Disorders (633) · Pathological Conditions, Signs and Symptoms (215) · Signs and Symptoms (204) · Neurologic Manifestations (195) · Pain (131) · Trigeminal Autonomic Cephalalgias (41) · Behavior (36) · Migraine Disorders (34) · Mental Disorders (26) · Pathologic Processes (23) · Immune System Diseases (18)
Sodium Chloride (16) · Exercise (15) · Acupuncture Therapy (13) · Musculoskeletal Manipulations (13) · Sumatriptan (12) · Transcranial Direct Current Stimulation (12) · Pituitary Adenylate Cyclase-Activating Polypeptide (9) · Cromakalim (8) · Dry Needling (8) · Manipulation, Osteopathic (8) · Saline Solution (8) · Topiramate (7) · Amitriptyline (6) · Control Groups (6) · Flunarizine (6)
Danish Headache Center (63) · Riphah International University (10) · ElectroCore INC (9) · NYU Langone Health (9) · Thomas Jefferson University (9) · University of Valencia (9) · Ankara City Hospital Bilkent (7) · Brigham and Women's Hospital (7) · Mayo Clinic (6) · Wake Forest University Health Sciences (6) · Cairo University (5) · Hacettepe University (5) · Johns Hopkins University (5) · Theranica (5) · University of Aarhus (5)
United States (200) · Denmark (76) · Turkey (Türkiye) (64) · Spain (29) · China (26) · Italy (25) · France (21) · Germany (21) · Pakistan (17) · Canada (15) · Belgium (14) · Israel (14) · United Kingdom (14) · Brazil (12) · Egypt (10)
Mia Minen, MD (5) · Rebecca E Wells, MD, MPH (5) · Stephen D Silberstein, MD (4) · Yao Jie Xie, PhD (4) · Adaliene VM Ferreira, PhD (3) · Elizabeth K Seng, Ph.D. (3) · Messoud Ashina (3) · Messoud Ashina, Prof. (3) · Messoud Ashina, Professor (3) · Mirza Obaid Baig, MSPT (3) · Nanna Arngrim, MD (3) · Anna Huguet, PhD (2) · Bradley Katz, MD (2)
PMID 20647241, PMID 25339342, PMID 31246132, PMID 32213509, PMID 32359776, PMID 10024117, PMID 10412281, PMID 12707434, PMID 12841373, PMID 15012658, PMID 15870415, PMID 16052775, PMID 16128874, PMID 16553016, PMID 16630694, PMID 16776700, PMID 16920676, PMID 17040330, PMID 17052034, PMID 17106618, PMID 17165292, PMID 17323720, PMID 17508165, PMID 17659990, PMID 18187725, PMID 18331805, PMID 18541041, PMID 18928574, PMID 19216763, PMID 19250995, PMID 19272275, PMID 19411439, PMID 19548407, PMID 19706829, PMID 19775434, PMID 19845788, PMID 19936616, PMID 20194385, PMID 20862509, PMID 21267044, PMID 21385086, PMID 21435214, PMID 21457242, PMID 21600053, PMID 21837291, PMID 21886108, PMID 22001666, PMID 22113647, PMID 22231691, PMID 22384463
2016 (2), 2019 (2), K01NS124911 (2), 1UG3AT013498-01 (1), 2023 (1), 2025 (1), K23AT008406 (1), K23AT009706 (1), K23AT013838 (1), K23NS096107 (1), P01AT009965 (1), P30DK056350 (1), R01AT007176 (1), R01AT007813 (1), R01AT011005 (1)