10 completed, 2 unknown. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 10, Unknown 2 |
Follow Cromakalim: new trials by email Literature Review of Cromakalim trials Research Report on Cromakalim
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab Levcromakalim, Placebo - Migraine Without Aura | Not applicable | Completed | Danish Headache Center | 16 | 2023-03-09 | 2023-10-24 |
| The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. Levcromakalim - Headache, Migraine With Aura | Not applicable | Unknown | Danish Headache Center | 20 | 2022-09-01 | 2023-03-22 |
| Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache Levcromakalim, Placebo - Post-Traumatic Headache | Not applicable | Completed | Danish Headache Center | 21 | 2022-03-21 | 2022-07-08 |
| Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine Levcromakalim, Sumatriptan, Saline - Migraine Without Aura, Headache | Not applicable | Completed | Danish Headache Center | 24 | 2022-03-15 | 2025-01-22 |
| Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura Levcromakalim, Saline - Headache, Migraine, Aura | Not applicable | Completed | Danish Headache Center | 35 | 2021-09-29 | 2023-05-17 |
| The Effects of Levcromakalim in Patients With Cluster Headache Levcromakalim, Saline - Cluster Headache | Not applicable | Completed | Danish Headache Center | 41 | 2021-06-04 | 2023-06-28 |
| Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM) Levcromakalim, Ivabradine, Placebo - Headache, Migraine Without Aura | Not applicable | Completed | Danish Headache Center | 37 | 2021-05-11 | 2026-01-08 |
| Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients Levcromakalim, Saline - Headache, Migraine | Not applicable | Completed | Danish Headache Center | 17 | 2019-07-09 | 2020-03-02 |
| The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers Levcromakalim, Saline - Hemodynamics of Cranial Arteries, Headache | Not applicable | Unknown | Danish Headache Center | 15 | 2019-04-01 | 2022-07-07 |
| Peripheral Nociceptive Effects of Levcromakalim Levcromakalim, Saline - Pain, Levcromakalim | Not applicable | Completed | Danish Headache Center | 20 | 2018-11-01 | 2019-01-23 |
| The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers. Levcromakalim, Saline - Dilatation of Cranial Arteries; MMA, STA and MCA, Headache | Not applicable | Completed | Danish Headache Center | 20 | 2018-06-26 | 2022-07-05 |
| Headache Inducing Effect of Cromakalim in Migraine Patients Levcromakalim, Saline - Headache, Migraine | Not applicable | Completed | Danish Headache Center | 16 | 2017-05-24 | 2018-06-19 |
Headache (7) · Migraine without Aura (4) · Migraine Disorders (3) · Epilepsy (2) · Pain (2) · Cluster Headache (1) · Migraine with Aura (1) · Post-Traumatic Headache (1)
Denmark (12)
Messoud Ashina (2) · Messoud Ashina, Prof. (2) · Hakan Ashina, MD (1) · Messoud Ashina, MD, PhD (1) · Messoud Ashina, Professor (1)
PMID 31292608, PMID 31535367, PMID 32806954, PMID 33768245, PMID 37917826, PMID 38127692, PMID 38181724, PMID 38501895, PMID 39161224, PMID 40624944, PMID 41930571