7 completed, 4 not yet recruiting, 3 unknown, 2 recruiting. 6 Not applicable, 6 Phase 4, 3 Phase 1, 2 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized, Open-Label, Multi-Center Study of Vestibular Migraine Prevention: Rimegepant Versus Flunarizine Non-inferiority Study Rimegepant, Flunarizine - Vestibular Migraine | Phase 2 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 400 | 2026-12-01 | 2026-08-07 |
| Comparison of Propranolol, Flunarizine and Their Combination in Preventing Migraine in Adults in a Tertiary Care Hospital in Bangladesh Propranolol 80 mg, Flunarizine 10 mg, Propranolol 40 mg + Flunarizine 10mg - Migraine Prophylaxis | Phase 4 | Not yet recruiting | Chittagong Medical College | 177 | 2026-07-01 | 2026-06-22 |
| An Open Label Pharmacokinetic Study of ASP-001 Formulations in Healthy Volunteers Flunarizine - Pharmacokinetic Analysis | Phase 1 | Completed | Aspartes Pharmaceuticals, Inc. | 11 | 2026-04-09 | 2026-10-06 |
| Comparative Efficacy of Flunarizine and Propanolol in Pediatric Migraine Flunarizine, Propranolol - Migraine | Not applicable | Recruiting | Muhammad Aamir Latif | 44 | 2025-09-01 | 2026-01-21 |
| Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine Without Aura Fu's Subcutaneous Needling, Flunarizine Hydrochloride - Migraine Without Aura | Phase 1 | Not yet recruiting | Guangzhou University of Chinese Medicine | 60 | 2025-09-01 | 2025-07-16 |
| Prospective Exploratory Study on rTMS for Migraine Under the Guidance of MEG rTMS, Sibelium - Migraine Disorders, Brain, rTMS Stimulation | Not applicable | Recruiting | Ruijin Hospital | 60 | 2025-02-06 | 2025-02-11 |
| Childhood Migraine Treatment Noninvasive Pulsed Radiofrequency vs Flunarizine Radiofrequency, flunarizine - Migraine Disease | Active not recruiting | Damla Yürük | 60 | 2024-10-01 | 2025-01-13 | |
| Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care Topiramate, Flunarizine, Amitriptyline - Migraine | Phase 4 | Not yet recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 460 | 2024-10-01 | 2024-07-12 |
| Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis Amitriptyline, Flunarizine 5mg - Migraine, Prophylaxis | Not applicable | Unknown | Shalamar Institute of Health Sciences | 84 | 2024-01-01 | 2023-12-29 |
| A Randomized Controlled Trial of Acupuncture in Treating Migraine Acupuncture combined with placebo, Sham acupuncture combined with flunarizine hydrochloride - Migraine Without Aura | Not applicable | Unknown | The Third Affiliated hospital of Zhejiang Chinese Medical University | 96 | 2021-04-21 | 2022-07-11 |
| Decoding Pain Sensitivity in Migraine With Multimodal Brainstem-based Neurosignature Flunarizine, healthy control - Migraine | Phase 4 | Unknown | Taipei Veterans General Hospital, Taiwan | 600 | 2021-02-26 | 2021-04-14 |
| Flunarizine for Treatment Resistant Absence Epilepsy Flunarizine Hydrochloride - Childhood Absence Epilepsy, Juvenile Absence Epilepsy | Phase 2 | Terminated | University of British Columbia | 9 | 2019-09-20 | 2023-12-01 |
| Evaluation of Efficacy and Safety of add-on Alpha-lipoic Acid on Migraine Prophylaxis in Adolescent Population Flunarizine 5mg, Alpha lipoic acid 300mg - Adolescent Migraine | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 60 | 2019-09-14 | 2023-07-25 |
| Comparison of Therapeutic Effects of Greater Occipital Nerve Block, Topiramate, and Flunarizine on Episodic Migraine Greater Occipital Nerve Block, Topiramate, Flunarizine - Migraine | Not applicable | Completed | Ataturk University | 120 | 2019-03-01 | 2020-01-21 |
| Study of Key Electro-acupuncture Technique on Migraine electro-acupuncture, flunarizine hydrochloride - Migraine | Not applicable | Completed | Shanghai University of Traditional Chinese Medicine | 2 | 2015-03-01 | 2020-02-05 |
| Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis Flunarizine, Topiramate - Chronic Migraine | Phase 4 | Completed | Taipei Veterans General Hospital, Taiwan | 62 | 2012-06-01 | 2015-12-24 |
| Efficacy and Tolerability of Flunarizine for the Treatment of Schizophrenia: Comparison With Haloperidol Flunarizine - Schizophrenia | Phase 4 | Completed | Ambulatório de Bipolaridade | 70 | 2004-09-01 | 2008-08-22 |
| A Drug Interaction Study of the Pharmacokinetics of Topiramate and FLUNARIZINE When Given Together or Separately Topiramate; flunarizine - Human Volunteers, Migraine | Phase 1 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 75 | 2003-03-01 | 2011-05-18 |
Migraine Disorders (9) · Migraine without Aura (2) · Epilepsy, Absence (1) · Myoclonic Epilepsy, Juvenile (1) · Schizophrenia (1)
Taipei Veterans General Hospital, Taiwan (2) · All India Institute of Medical Sciences, Bhubaneswar (1) · Ambulatório de Bipolaridade (1) · Aspartes Pharmaceuticals, Inc. (1) · Ataturk University (1) · Chittagong Medical College (1) · Damla Yürük (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Guangzhou University of Chinese Medicine (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Muhammad Aamir Latif (1) · Ruijin Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Shalamar Institute of Health Sciences (1) · Shanghai University of Traditional Chinese Medicine (1)
China (4) · Pakistan (2) · Turkey (Türkiye) (2) · Australia (1) · Bangladesh (1) · Brazil (1) · Canada (1) · India (1) · Taiwan (1)
Chuanlong Zhou (1) · Ishafaq Ahmed, FCPS (1) · Jian Pei, Ph.D (1) · Jian Sun, M.D. (1) · Muhammad Zia-ur-Rehman, FCPS (1) · Mujeeb-ur-Rehman Abid Butt, FCPS (1) · Peter Schrader, MBBS, FRACP (1) · Rituparna Maiti, MD (1) · Shuu-Jiun Wang, M.D. (1)
PMID 14510929, PMID 15822542, PMID 16340383, PMID 17300356, PMID 17441971, PMID 17445114, PMID 19192440, PMID 19719543, PMID 25386478, PMID 30259200, PMID 3052850, PMID 34554691, PMID 35281991, PMID 35957963, PMID 36268304, PMID 37563914, PMID 38788888, PMID 40859286, PMID 41214533, PMID 41430107