99 completed, 27 unknown, 14 recruiting, 8 terminated. 139 Not applicable, 9 Phase 2, 6 Phase 4, 3 Phase 3, 2 Phase 1.
Follow Manipulation, Osteopathic: new trials by email Literature Review of Manipulation, Osteopathic trials Research Report on Manipulation, Osteopathic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OMT for Adhesive Capsulitis Intra-articular Injection, Osteopathic Manipulative Therapy (OMT) - Adhesive Capsulitis of the Shoulder, Frozen Shoulder | Phase 4 | Not yet recruiting | University Hospitals Cleveland Medical Center | 300 | 2026-12-01 | 2026-10-05 |
| OMT for Overhead Throwing Performance: A Study on Shoulder and Hip Interventions Osteopathic Manipulative Treatment - Pitch, Baseball Pitcher | Not applicable | Not yet recruiting | William Carey University | 15 | 2026-10-14 | 2026-10-16 |
| The Impact of Osteopathic Manipulative Treatment on Pelvic Floor Dysfunction, Activity, and Gait in Female Runners Osteopathic Manipulative Treatment (OMT) - Pelvic Floor Disfunction | Not applicable | Recruiting | Elizabeth Perrero | 10 | 2026-09-05 | 2026-09-23 |
| Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations Osteopathic Manipulation, Osteopathic manipulation, Sham - No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers | Not applicable | Recruiting | Lake Erie College of Osteopathic Medicine | 50 | 2026-09-01 | 2026-09-23 |
| The Effect of Osteopathic Manipulative Techniques on Human Tear Composition Osteopathic Manipulative Treatment, Sham - No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers | Not applicable | Enrolling by invitation | Lake Erie College of Osteopathic Medicine | 30 | 2026-09-01 | 2026-08-25 |
| Short-term Effects of Osteopathic Manipulations on Heart Rate Variability in Lung Cancer Patients - A Randomized Pilot Study Osteopathic treatment, Quality of life assessment, Anxiety assessment - Lung Cancer | Not applicable | Recruiting | Centre Hospitalier Henri Duffaut - Avignon | 80 | 2026-08-31 | 2026-10-21 |
| Osteopathy in Postpartum Lumbopelvic Pain Core Stabilization Exercises, Patient Education, Osteopathic Manipulative Treatment - Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain | Not applicable | Active not recruiting | Halic University | 45 | 2026-06-01 | 2026-09-09 |
| Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study Osteopathic Manipulative Treatment (OMT) - Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics | Not applicable | Not yet recruiting | Edward Via Virginia College of Osteopathic Medicine | 30 | 2026-06-01 | 2026-06-05 |
| Impact of OMT on the Symptoms of Dysmenorrhea Osteopathic Manipulative Treatment (OMT) - Dysmenorrhea | Not applicable | Recruiting | Western University of Health Sciences | 30 | 2026-04-30 | 2026-09-30 |
| Chronic Low Back Pain and Osteopathic Manipulation Treatment Usual VA Care, Osteopathic manipulative treatment - Chronic Low Back Pain (CLBP), Low Back Pain | Not applicable | Recruiting | Edward Hines Jr. VA Hospital | 48 | 2026-03-02 | 2026-05-22 |
| Comparing Efficacy of Osteopathic Manipulation vs. Wrist Immobilization for Carpal Tunnel Syndrome Osteopathic Manipulative Treatment, Wrist Immobilizer - Carpal Tunnel Syndrome (CTS) | Not applicable | Recruiting | New York Institute of Technology | 10 | 2026-03-01 | 2026-02-25 |
| How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain Osteopathic Manipulative Treatment - Chronic Low Back Pain (CLBP) | Not applicable | Recruiting | Edward Via Virginia College of Osteopathic Medicine | 20 | 2025-11-05 | 2026-05-14 |
| Osteopathic Manipulative Treatment for Pitch Performance in Baseball Players: A Study on Shoulder and Hip Interventions Osteopathic Manipulative Treatment - Pitch, Baseball Pitcher | Not applicable | Enrolling by invitation | William Carey University | 30 | 2025-10-14 | 2025-10-14 |
| Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study Osteopathic Manipulative Therapy - Primary Headaches (Migraines, Tension, Cluster Headaches) | Not applicable | Completed | Edward Via Virginia College of Osteopathic Medicine | 31 | 2025-08-05 | 2026-05-06 |
| Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects Osteopathic Manipulative Treatment, Sham (No Treatment) - Parkinsons Disease, Sleep | Not applicable | Recruiting | New York Institute of Technology | 32 | 2025-08-01 | 2026-06-29 |
| Adding Ujjayi Pranayama to Osteopathic Manipulative Treatment on Pulmonary Functions and Functional Capacity in College Students With Upper Cross Syndrome osteopathic manipulative tratment only, ujjayi pranayama and osteopathic manipulative treatment - Osteopathic Manipulation, Ujjayi Pranayama | Not applicable | Completed | Al-Zaytoonah University of Jordan | 40 | 2025-08-01 | 2025-11-19 |
| ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study Osteopathic Manipulative Treatment (OMT), Sham Light Touch, Exercise Protocol - Healthy | Not applicable | Active not recruiting | Western University of Health Sciences | 30 | 2025-07-14 | 2026-08-19 |
| Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders? Osteopathic Manipulative Treatment (OMT), Sham Light touch arm - Headache Disorders, Headache | Not applicable | Not yet recruiting | New York Institute of Technology | 20 | 2025-04-08 | 2025-03-17 |
| The Utility of Osteopathic Manipulative Medicine in Weaning Patients from the Ventilator Pilot Trial Osteopathic Manipulative Treatment - Respiratory Failure, Osteopathy in Diseases Classified Elsewhere | Not applicable | Not yet recruiting | Oklahoma State University Center for Health Sciences | 20 | 2025-03-17 | 2025-03-24 |
| Osteopathic Manipulative Techniques in Collegiate Dancers Osteopathic Manipulative Treatment (OMT) - Osteopathic Manipulative Treatment (OMT), Dance Therapy | Not applicable | Completed | Edward Via Virginia College of Osteopathic Medicine | 15 | 2025-02-01 | 2025-03-05 |
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Low Back Pain (19) · Pain (14) · Headache (9) · Premature Birth (8) · Migraine Disorders (7) · Neck Pain (7) · Parkinson Disease (5) · Breast Feeding (4) · Carpal Tunnel Syndrome (4) · COVID-19 (3) · Headache Disorders (3) · Post-Concussion Syndrome (3) · Asthma (2) · Back Pain (2) · Brain Concussion (2)
Edward Via Virginia College of Osteopathic Medicine (11) · European Institute for Evidence Based Osteopathic Medicine (10) · Michigan State University (8) · New York Institute of Technology (8) · Come Collaboration (6) · Western University of Health Sciences (6) · A.T. Still University of Health Sciences (5) · University of North Texas Health Science Center (5) · Assistance Publique - Hôpitaux de Paris (4) · Lake Erie College of Osteopathic Medicine (3) · Studio Osteopatico Busto Arsizio (3) · University of California, San Diego (3) · Alanya Alaaddin Keykubat University (2) · Corewell Health South (2) · Des Moines University (2)
United States (88) · Italy (26) · France (14) · Brazil (8) · Turkey (Türkiye) (5) · Canada (4) · Egypt (2) · Austria (1) · Belgium (1) · Spain (1) · United Kingdom (1)
Hollis H King, DO, PhD (4) · Francesco Cerritelli, MS, DO (3) · Brian F Degenhardt, DO (2) · Daniel Cawley, DC, MS, MSHS (2) · David Duriancik, Ph.D. (2) · Jacek Cholewicki, PhD (2) · Norman P Reeves, PhD (2) · Sheldon Yao, DO (2) · Abby Rhoads, DO (1) · Albert J Kozar DO, FAOASM, R-MSK (1) · Alberto Manassero, MD (1) · Alejandro Gugliucci, MD, PhD (1) · Alexa Craig, MD (1) · Alphonsa Thomas, DO (1) · Amber Hood, DFS (1)
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U19AT006057 (2), K23AT003304 (1), P50AT000008 (1)