26 completed, 7 unknown, 5 terminated, 4 recruiting. 46 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 46 | Completed 26, Unknown 7, Terminated 5, Recruiting 4, Not yet recruiting 3, Withdrawn 1 |
| Phase 2 | 7 | Completed 3, Not yet recruiting 1, Recruiting 1, Terminated 1, Unknown 1 |
Follow Gastrointestinal Hemorrhage: new trials by email Literature Review of Gastrointestinal Hemorrhage trials Research Report on Gastrointestinal Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding Chlorophyllin, Sodium Copper Complex, Placebo - Radiation Proctitis, Gastrointestinal Hemorrhage | Phase 3 | Not yet recruiting | Tata Memorial Centre | 200 | 2026-09-15 | 2026-09-23 |
| Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding Trimebutine Maleate, Placebo - Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 100 | 2026-09-01 | 2026-08-06 |
| Routine Use of Potassium Competitive Acid Blocker vs. Guideline-Directed Gastrointestinal Protection Strategy in Acute Myocardial Infarction Zastaprazan, Proton Pump Inhibitors (PPI) - Acute Myocardial Infarction (AMI), Gastrointestinal Bleeding | Phase 3 | Recruiting | Samsung Medical Center | 5000 | 2026-06-23 | 2026-06-26 |
| Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke) Tegoprazan 50 mg, Placebo - Ischemic Stroke, Ischemic Stroke, Acute | Phase 3 | Recruiting | Hanyang University Guri Hospital | 1524 | 2026-01-26 | 2026-07-08 |
| Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock low-titer O-group whole blood, 1:1:1 component transfusion, ABO- and Rh-compatible whole blood - Hemorrhage, Hemorrhagic Shock | Phase 3 | Not yet recruiting | Xijing Hospital | 180 | 2025-09-01 | 2025-08-19 |
| Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism Omeprazole 20 mg Oral Tablet, Placebo - Venous Thromboembolism, Gastro Intestinal Bleeding | Phase 3 | Recruiting | Ottawa Hospital Research Institute | 360 | 2024-11-06 | 2026-07-22 |
| Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding Metoclopramide, Placebo - Upper Gastrointestinal Bleeding | Phase 3 | Completed | Universidad Autonoma de Nuevo Leon | 50 | 2023-03-01 | 2024-10-09 |
| Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure polyethylene glycol, sodium phosphate, polyethylene glycol + ascorbic acid - Colon Cancer, Inflammatory Bowel Diseases | Phase 3 | Completed | Region Skane | 147 | 2023-02-01 | 2024-02-28 |
| Faecal Microbiota Transplantation for Liver Cirrhosis Faecal microbiota transplantation, Placebo - Liver Cirrhosis | Phase 2 / Phase 3 | Recruiting | University of Aarhus | 220 | 2021-07-01 | 2025-01-24 |
| Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure 2% Diltiazem ointment with 1.5% lidocaine, 0.3% Nifedipine ointment with 1.5% lidocaine - Fissure in Ano, Rectal Diseases | Phase 2 / Phase 3 | Unknown | University of Calgary | 430 | 2021-06-01 | 2021-05-14 |
| Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding Tranexamic acid, Standard of care - Gastro Intestinal Bleeding | Phase 3 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 160 | 2020-11-01 | 2021-03-09 |
| Topical Vitamin E Ovules for the Treatment of Hemorrhoids Vitamin E ovules, Prednisolone ointment - Bleeding Anal, Pain | Phase 3 | Unknown | Hospital General Universitario Elche | 120 | 2020-05-01 | 2020-04-24 |
| Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial Placebo (0.9% saline), Pantoprazole - Gastrointestinal Hemorrhage (Clinically Important, Upper) | Phase 3 | Completed | McMaster University | 4800 | 2018-07-09 | 2024-09-20 |
| Pediatric Intensive Care Ulcer Prophylaxis Pilot Trial Pantoprazole, Placebo (for pantoprazole) - Gastrointestinal Hemorrhage | Phase 3 | Completed | McMaster University | 116 | 2017-01-09 | 2020-09-02 |
| Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support Prophylactic treatment with Wilfactin - Heart Failure | Phase 3 | Terminated | University Hospital, Lille | 31 | 2016-01-20 | 2019-07-11 |
| Efficacy of Octreotide on Blood and Iron Requirements in Patients With Anemia Due to Angiodysplasias Octreotide - Angiodysplasia, Vascular Malformations | Phase 3 | Completed | Radboud University Medical Center | 62 | 2015-09-01 | 2023-05-24 |
| Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients Ilaprazole, Omeprazole, Ilaprazole tablet - Peptic Ulcer Hemorrhage | Phase 3 | Completed | Livzon Pharmaceutical Group Inc. | 540 | 2014-10-01 | 2017-12-06 |
| Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients Esomeprazole, Cimetidine - Stress Ulcer Prophylaxis | Phase 3 | Completed | AstraZeneca | 343 | 2014-07-01 | 2017-03-10 |
| Haemorrhage Alleviation With Tranexamic Acid- Intestinal System Tranexamic Acid, Placebo - Gastrointestinal Bleeding | Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 12009 | 2013-07-01 | 2020-04-17 |
| High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer Esomeprazole Na, Cimetidine, Esomeprazole Mg - Bleeding Peptic Ulcer | Phase 3 | Completed | AstraZeneca | 239 | 2013-02-01 | 2016-03-08 |
Showing 20 of 46. Sign in to see all of them.
Peptic Ulcer Hemorrhage (6) · Hematemesis (4) · Hemorrhage (4) · Fibrosis (3) · Anemia (2) · Cerebrovascular Disorders (2) · Colonic Neoplasms (2) · Hypertension, Portal (2) · Inflammatory Bowel Diseases (2) · Liver Diseases (2) · Melena (2) · Peptic Ulcer (2) · Acute Coronary Syndrome (1) · Anemia, Refractory (1)
Digestive System Diseases (46) · Gastrointestinal Diseases (46) · Pathologic Processes (46) · Pathological Conditions, Signs and Symptoms (46) · Hemorrhage (42) · Cardiovascular Diseases (6) · Intestinal Diseases (6) · Signs and Symptoms (6) · Signs and Symptoms, Digestive (5) · Vascular Diseases (5) · Gastroenteritis (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Vomiting (4)
Omeprazole (4) · Pantoprazole (4) · Esomeprazole (3) · Cimetidine (2) · Gastric Lavage (2) · Metoclopramide (2) · Polyethylene Glycols (2) · Tranexamic Acid (2) · Amoxicillin (1) · Ascorbic Acid (1) · Aspirin (1) · Capsule Endoscopy (1) · Clarithromycin (1) · Clopidogrel (1) · Diatrizoate Meglumine (1)
AstraZeneca (4) · Chinese University of Hong Kong (4) · McMaster University (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Bausch Health Americas, Inc. (1) · Casa Sollievo della Sofferenza IRCCS (1) · Centre Hospitalier Universitaire, Amiens (1) · Cogentus Pharmaceuticals (1) · Dr Vipul Jairath (1) · Hanyang University Guri Hospital (1) · Hospital Clinic of Barcelona (1) · Hospital General Universitario Elche (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Hospital Universitari de Bellvitge (1)
China (8) · France (7) · Canada (6) · United Kingdom (5) · United States (5) · Spain (4) · Germany (3) · South Korea (3) · Australia (2) · Denmark (2) · Hong Kong (2) · India (2) · Italy (2) · Mexico (2) · Netherlands (2)
Tore Lind, MD (2) · Andriulli Angelo, MD (1) · Antonio Soriano, M D, Ph D (1) · Cheol Min Shin, MD (1) · Christopher Fraser, MB BCH, MD, FRCP (1) · Deborah Cook, MD (1) · Deborah Siegal, MD (1) · Ervin Toth, MD PhD (1) · Francis KL Chan, MD (1) · Haleema Shakur-Still (1) · Henry KM Joeng, MBBS (1)
PMID 19086953, PMID 19221370, PMID 20151726, PMID 20925534, PMID 21181319, PMID 25245464, PMID 25409738, PMID 25432532, PMID 25926146, PMID 25956718, PMID 26581750, PMID 27012778, PMID 27619827, PMID 27641510, PMID 28070941, PMID 28533916, PMID 29638148, PMID 29720248, PMID 31362765, PMID 32563378, PMID 34663491, PMID 35041627, PMID 37644556, PMID 37968012, PMID 38057875, PMID 38158089, PMID 38706390, PMID 38875111, PMID 39938959, PMID 40379131, PMID 41213683, PMID 42186360, PMID 42674788
2009 (1), 2015 (1)