33 completed, 10 unknown, 4 withdrawn, 3 not yet recruiting. 19 Not applicable, 14 Phase 4, 6 Phase 3, 5 Phase 2, 2 Early Phase 1.
Follow Peptic Ulcer Hemorrhage: new trials by email Literature Review of Peptic Ulcer Hemorrhage trials Research Report on Peptic Ulcer Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Potassium-competitive Acid Blocker Versus Double Dose Proton Pump Inhibitors in High High-risk Peptic Ulcer Bleeding Vonoprazon, Esomeprazole - Bleeding | Not applicable | Not yet recruiting | National Cheng-Kung University Hospital | 108 | 2026-09-01 | 2026-08-20 |
| Tegoprazan Versus Lansoprazole for Endoscopic Ulcer Healing in Bleeding Peptic Ulcers Tegoprazan tablet, Lansoprazole capsules - Peptic Ulcer Bleeding | Phase 2 | Recruiting | Universitas Indonesia | 162 | 2026-08-06 | 2026-08-21 |
| Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing Esomeprazole (Intravenous), Esomeprazole (Oral), Sucralfate Suspension - Early Gastric Cancer, Gastric Dysplasia | Phase 4 | Not yet recruiting | LanZhou University | 120 | 2026-04-20 | 2026-03-23 |
| The Use of OTSC in LBGDU to Standard Endoscopic Hemostatic Methods Over-the-scope Clips, Hemo-clipping - Bleeding Peptic Ulcer | Not applicable | Withdrawn | Chinese University of Hong Kong | 2025-10-01 | 2025-01-24 | |
| Tegoprazan And Lansoprazole Effectiveness in Bleeding Peptic Ulcer Treatment Tegoprazan, Lansoprazole - Peptic Ulcer Bleeding | Not applicable | Recruiting | Mario Steffanus | 162 | 2025-05-01 | 2025-05-29 |
| Phase II Clinical Study of Vonorasan Fumarate Injection in the Treatment of Peptic Ulcer Bleeding Vonorasan fumarate injection1, Vonorasan fumarate injection2, Esomeprazole sodium for injection - Peptic Ulcer Bleeding | Phase 2 | Not yet recruiting | Shandong New Time Pharmaceutical Co., LTD | 150 | 2025-02-01 | 2025-01-20 |
| Diagnostic Performance of CIM for Helicobacter Pylori Infection in Patients With Peptic Ulcer Bleeding Helicobacter Pylori Infection, Peptic Ulcer Hemorrhage | Unknown | Mahidol University | 135 | 2024-03-01 | 2024-02-22 | |
| Anticoagulation With Enhanced Gastrointestinal Safety Clinician Notification with Nurse Facilitation (CNNF), Wait list control - Upper Gastrointestinal Bleeding, Peptic Ulcer Hemorrhage | Not applicable | Completed | University of Michigan | 341 | 2022-10-05 | 2024-04-30 |
| Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding Tranexamic Acid Powder - Peptic Ulcer Hemorrhage | Not applicable | Completed | National Cheng-Kung University Hospital | 60 | 2022-03-24 | 2023-05-06 |
| Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis Vonoprazan, PPIs IV infusion - Peptic Ulcer With Haemorrhage | Early Phase 1 | Completed | Uayporn Kaosombatwattana | 194 | 2021-09-01 | 2023-10-27 |
| ClearEndoclip Versus EZ Clip for Upper Gastrointestinal Ulcer Bleeding Endoscopic hemostasis with clip - Peptic Ulcer Hemorrhage | Not applicable | Unknown | Ajou University School of Medicine | 176 | 2020-08-24 | 2020-09-02 |
| Oral Omeprazole in Bleeding Peptic Ulcer Omeprazole - Bleeding Peptic Ulcer | Early Phase 1 | Unknown | Assiut University | 100 | 2019-11-01 | 2019-11-25 |
| Registry for Upper Gastrointestinal Bleeding Upper GI Endoscopy - Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage | Completed | AdventHealth | 2999 | 2019-10-01 | 2022-02-17 | |
| Over-the-scope Clip Versus Through-the-scope Clip for Endoscopic Hemostasis of High Risk Bleeding Peptic Ulcers OTSC, TTS clip - Bleeding Peptic Ulcer | Not applicable | Unknown | Azienda USL Modena | 88 | 2018-10-26 | 2023-05-06 |
| Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding Omeprazole High dose, Omeprazole Low dose - Gastroduodenal Ulcer, Marginal Ulcer | Phase 4 | Withdrawn | Damascus Hospital | 2017-12-01 | 2018-07-10 | |
| Efficacy of Low Dose Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding intermittent (40mg as a bolus injection daily for 72hours) - Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage | Not applicable | Unknown | Samsung Changwon Hospital | 200 | 2016-04-15 | 2020-10-22 |
| Long-term Oral Esomeprazole for Prevention of Peptic Ulcer Rebleeding in High-risk Patients oral esomeprazole 20 mg twice daily, oral esomeprazole 20 mg once daily - Peptic Ulcer Hemorrhage | Phase 4 | Completed | Hsiu-Chi Cheng | 268 | 2015-04-01 | 2022-02-22 |
| Study to Evaluate Efficacy and Safety of Wound Dressing Solution Containing EGF in Patients With Peptic Ulcers Bleeding CEGP003, Injection Tx - Peptic Ulcer Bleeding | Not applicable | Completed | CGBio Inc. | 76 | 2014-10-15 | 2018-03-19 |
| Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients Ilaprazole, Omeprazole, Ilaprazole tablet - Peptic Ulcer Hemorrhage | Phase 3 | Completed | Livzon Pharmaceutical Group Inc. | 540 | 2014-10-01 | 2017-12-06 |
| Risk Factors of Rebleeding After Peptic Ulcer Bleeding: a Nationwide Cohort Study Peptic Ulcer Bleeding | Completed | Joon Sung Kim | 892 | 2014-04-01 | 2016-08-04 |
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Peptic Ulcer (12) · Hemorrhage (8) · Gastrointestinal Hemorrhage (5) · Thrombosis (2) · Ulcer (2) · Coronary Occlusion (1) · Hematemesis (1) · Hypoalbuminemia (1) · Melena (1) · Shock (1) · Stomach Neoplasms (1) · Stomach Ulcer (1)
Digestive System Diseases (55) · Gastrointestinal Diseases (55) · Pathologic Processes (55) · Pathological Conditions, Signs and Symptoms (55) · Gastrointestinal Hemorrhage (50) · Hemorrhage (47) · Duodenal Diseases (13) · Intestinal Diseases (13) · Stomach Diseases (13) · Cardiovascular Diseases (2) · Embolism and Thrombosis (2) · Vascular Diseases (2) · Blood Protein Disorders (1) · Coronary Disease (1) · Digestive System Neoplasms (1)
Esomeprazole (8) · Omeprazole (7) · Pantoprazole (5) · Argon Plasma Coagulation (3) · Lansoprazole (3) · Hemostasis, Endoscopic (2) · Proton Pump Inhibitors (2) · Risk Factors (2) · ilaprazole (2) · tegoprazan (2) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (1) · Amoxicillin (1) · Cimetidine (1) · Clarithromycin (1) · Early Intervention, Educational (1)
Chinese University of Hong Kong (9) · National Cheng-Kung University Hospital (5) · Odense University Hospital (4) · AstraZeneca (2) · Damascus Hospital (2) · Kaohsiung Veterans General Hospital. (2) · Livzon Pharmaceutical Group Inc. (2) · Lotung Poh-Ai Hospital (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · AdventHealth (1) · Ajou University School of Medicine (1) · Assiut University (1) · Azienda USL Modena (1) · CGBio Inc. (1) · Changhua Christian Hospital (1)
China (12) · Taiwan (10) · South Korea (6) · Denmark (4) · United States (4) · Indonesia (2) · Spain (2) · Syria (2) · Thailand (2) · Belgium (1) · France (1) · Greece (1) · Hungary (1) · Italy (1) · Poland (1)
Bor-Shyang Sheu, MD (3) · Hwai-jeng Lin, M.D. (2) · Alan Barkun, MD (1) · Byung-Wook Kim, Ph.D. (1) · Cheol Min Shin, MD (1) · Don Haeng Lee, MD. PhD. (1) · Enders KW Ng, MD (1) · Hasan Maulahela, MD, PhD (1) · Henry KM Joeng, MBBS (1) · Hiun-Suk Chae, Professor (1) · Hsiu-Chi Cheng, MD, PhD (1) · Hsueh-Chien Chiang, MD (1)
PMID 24658598, PMID 26417980, PMID 29802172, PMID 31222633, PMID 10406244, PMID 10452677, PMID 10811322, PMID 11281437, PMID 15128344, PMID 16494583, PMID 17382282, PMID 17608775, PMID 18205663, PMID 18205666, PMID 18300349, PMID 18423628, PMID 18684171, PMID 18753649, PMID 20427808, PMID 20614440, PMID 21490373, PMID 22619883, PMID 23318399, PMID 23580408, PMID 23881695, PMID 24256098, PMID 24846521, PMID 25197649, PMID 25278682, PMID 25308912, PMID 25440395, PMID 25730283, PMID 26266385, PMID 26581750, PMID 27004241, PMID 28242110, PMID 28456631, PMID 28497645, PMID 28751088, PMID 29803838, PMID 29949497, PMID 30585835, PMID 30648911, PMID 31278206, PMID 31634917, PMID 32242355, PMID 32426894, PMID 32563378, PMID 32828873, PMID 33765303
K23DK118179 (1)