8 completed, 2 recruiting, 2 unknown, 1 not yet recruiting. 7 Not applicable, 2 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 3, Recruiting 2, Terminated 1, Withdrawn 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow Melena: new trials by email Literature Review of Melena trials Research Report on Melena
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Cancer AI group, Serial group, Standard colonoscopy group - Abdominal Pain, Black Stools | Not yet recruiting | Limian Er | 1200 | 2026-02-26 | 2026-01-14 | |
| A Study to Evaluate the Performance of a Wireless Optical Sensor Capsule in Detection of UGIB Hemopill, OGD - Melena, Gastrointestinal Bleeding | Not applicable | Recruiting | Chinese University of Hong Kong | 193 | 2025-11-05 | 2026-04-22 |
| PillSense for Suspected Upper Gastrointestinal Bleeding PillSense System - Bleeding Ugi | Not applicable | Recruiting | Tan Tock Seng Hospital | 84 | 2024-07-18 | 2024-12-10 |
| Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding Metoclopramide, Placebo - Upper Gastrointestinal Bleeding | Phase 3 | Completed | Universidad Autonoma de Nuevo Leon | 50 | 2023-03-01 | 2024-10-09 |
| Magnetically Controlled Capsule Endoscopy First vs. Standard Algorithm in Patients With Melena MCE first - Melena | Not applicable | Withdrawn | Changhai Hospital | 2020-12-01 | 2020-09-29 | |
| Study of Early Endocapsule (EC) in Clinical Decision Unit Versus Standard of Care Work-up for GI Bleeding Video Capsule Endoscopy - Gastro Intestinal Bleeding, Hematemesis | Not applicable | Completed | Christopher Marshall | 35 | 2020-02-04 | 2023-07-10 |
| The Role of Push Enteroscopy in Patients With Passing Melena With Nondiagnostic EGD. Push enteroscopy (PE), Colonoscopy - Melena Due to Gastrointestinal Hemorrhage | Not applicable | Completed | Mahidol University | 77 | 2019-07-08 | 2024-08-29 |
| Point of Care Testing of Platelet Function in Patients With Acute Upper Gastrointestinal Bleeding blood taking - Hematemesis, Melena | Completed | Chinese University of Hong Kong | 476 | 2017-01-03 | 2020-01-23 | |
| Comparing Early Capsule Deployment to Current Standard of Care for Management of Gastrointestinal Bleeding Early Video Capsule Endoscopy - Melena, Gastrointestinal Hemorrhage | Not applicable | Completed | University of Massachusetts, Worcester | 87 | 2015-04-19 | 2018-08-07 |
| Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed. Erythromycin, Metoclopromide - Upper Gastrointestinal Bleeding | Not applicable | Terminated | Texas Tech University Health Sciences Center, El Paso | 4 | 2014-06-01 | 2021-03-04 |
| Tranexamic Acid for Upper Gastrointestinal Bleeding Early intravenous tranexamic acid administration, placebo - Acute Upper Gastrointestinal Hemorrhage | Phase 3 | Unknown | Seoul National University Hospital | 414 | 2012-10-01 | 2014-05-16 |
| Epidemiological Study of Colorectal Cancer in WuHan Diarrhea, Constipation | Unknown | Wuhan Pu-Ai Hospital | 1 | 2012-06-01 | 2013-05-27 | |
| Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding Thalidomide - Arteriovenous Malformation, Hereditary Hemorrhagic Telangiectasia | Phase 2 | Completed | Northport Veterans Affairs Medical Center | 14 | 2006-10-01 | 2011-08-02 |
| Short Course Terlipressin for Control of Acute Variceal Bleeding Terlipressin, Terlipressin & then Dummy - Hemorrhage, Esophageal Varices | Phase 4 | Completed | Aga Khan University | 130 | 2006-08-01 | 2008-09-25 |
| The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed Terlipressin, Octreotide - Portal Hypertension, Cirrhosis | Phase 4 | Completed | Aga Khan University | 320 | 2004-05-01 | 2007-12-05 |
Gastrointestinal Hemorrhage (10) · Hematemesis (8) · Constipation (2) · Diarrhea (2) · Hypertension, Portal (2) · Abdominal Pain (1) · Angiodysplasia (1) · Arteriovenous Malformations (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Emergencies (1) · Esophageal and Gastric Varices (1) · Fibrosis (1) · Hemorrhage (1)
Digestive System Diseases (15) · Gastrointestinal Diseases (15) · Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Hemorrhage (14) · Signs and Symptoms (10) · Signs and Symptoms, Digestive (10) · Vomiting (8) · Gastrointestinal Hemorrhage (5) · Liver Diseases (2) · Neurologic Manifestations (2) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Colonic Diseases (1) · Congenital Abnormalities (1)
Metoclopramide (2) · Terlipressin (2) · Capsule Endoscopy (1) · Colonoscopy (1) · Double-Balloon Enteroscopy (1) · Drug Delivery Systems (1) · Endoscopy (1) · Erythromycin (1) · Erythromycin Estolate (1) · Octreotide (1) · Thalidomide (1)
Aga Khan University (2) · Chinese University of Hong Kong (2) · Changhai Hospital (1) · Christopher Marshall (1) · Limian Er (1) · Mahidol University (1) · Northport Veterans Affairs Medical Center (1) · Seoul National University Hospital (1) · Tan Tock Seng Hospital (1) · Texas Tech University Health Sciences Center, El Paso (1) · Universidad Autonoma de Nuevo Leon (1) · University of Massachusetts, Worcester (1) · Wuhan Pu-Ai Hospital (1)
United States (4) · China (2) · Pakistan (2) · Hong Kong (1) · Mexico (1) · Singapore (1) · South Korea (1) · Thailand (1)
Saeed S Hamid, FRCP, FACG (2) · Atul Kumar, MD (1) · Cheol Min Shin, MD (1) · Christopher Marshall, MD (1) · David Cave, MD, PhD (1) · Dr Ng Wee Khoon (1) · James Gossage, MD (1) · Kyuseok Kim, MD (1) · Louis HS Lau, FRCP (1) · Mohamed O Othman, MD (1) · Salih Mohammad, FCPS; MACG (1) · Sang Hyub Lee, MD (1) · Shahab Abid, FCPS, FACG (1)