Peptic Ulcer: Clinical Trials

369 trials for Peptic Ulcer, newest first

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244 completed, 53 unknown, 28 recruiting, 17 not yet recruiting. 86 Not applicable, 80 Phase 3, 66 Phase 4, 30 Phase 2, 27 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable86Completed 36, Unknown 27, Recruiting 10, Not yet recruiting 7, Terminated 4, Active not recruiting 1, Enrolling by invitation 1
Phase 380Completed 65, Terminated 5, Unknown 5, Recruiting 4, Not yet recruiting 1
Phase 466Completed 44, Recruiting 7, Withdrawn 5, Not yet recruiting 4, Unknown 4, Active not recruiting 1, Terminated 1
Phase 230Completed 22, Unknown 4, Terminated 2, Suspended 1, Withdrawn 1
Phase 127Completed 24, Recruiting 1, Terminated 1, Withdrawn 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy
Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy
Not yet recruitingHospital de Mataró602026-12-012026-05-26
Vonoprazan High-Dose Dual VS Levofloxacin Concomitant
Vonoprazan, Levofloxacin 500mg - Helicobacter Pylori Infection, Peptic Ulcer Disease
Phase 4Not yet recruitingDamascus Hospital1502026-11-012026-06-03
Phase 3 to Evaluate the Efficacy and Safety of DWP14012 in Patients With Gastric Ulcer
DWP14012 40mg (Fexuprazan), Lansoprazole 30mg - Gastric Ulcer
Phase 3Not yet recruitingDaewoong Pharmaceutical Co. LTD.3842026-10-152026-07-28
Laparoscopic Falciform Ligament Flap Versus Omental Patch for Perforated Peptic Ulcers
Laparoscopic Falciform Ligament Flap Repair, Laparoscopic Omental Patch Repair - Perforated Peptic Ulcer, Peptic Ulcer Perforation
Not applicableNot yet recruitingAssiut University702026-10-012026-09-10
PPI Dosing Per CYP2C19 Genotype
CYP2C19 based dosing Proton Pump Inhibitors, Conventional proton pump inhibitor dose - Gastroesophageal Reflux Disease With Esophagitis
Phase 4Not yet recruitingUniversity of Florida2002026-10-012026-09-28
Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication
Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication - Gastroesophageal Reflux Disease, Hiatal Hernia
RecruitingMinia University4702026-09-202026-09-22
Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction
Proximal gastrectomy with double-tract reconstruction - Gastric Adenocarcinoma, Adenocarcinoma of the Esophagogastric Junction
Not yet recruitingThe First Affiliated Hospital with Nanjing Medical University2502026-08-152026-09-02
Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice
Peptic Ulcer, NSAID-Induced Peptic Ulcer
Not yet recruitingDaewoong Pharmaceutical Co. LTD.70002026-04-302026-04-30
The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication
Laparoscopic transit bipartition with Metallic Anastomotic Clip and Circular Fundocorporeal Gastroplication, Laparoscopic transit bipartition (gastroenteroanastomosis and entero-enteric anastomosis) use the Metallic Anastomotic Clip and with sleeve gastrectomy, laparoscopic duodenal transit bipartition using the Metallic Anastomotic Clip with circular fundocorporeal gastroplication without gastrectomy - Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight
Not applicableRecruitingThe Society of Bariatric and Metabolic Surgeons of Kazakhstan902026-04-302026-05-07
Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing
Esomeprazole (Intravenous), Esomeprazole (Oral), Sucralfate Suspension - Early Gastric Cancer, Gastric Dysplasia
Phase 4Not yet recruitingLanZhou University1202026-04-202026-03-23
Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication
vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen) - Helicobacter Pylori Infection, Dyspepsia
Phase 4RecruitingBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh802026-04-152026-04-22
Predicting Peptic Complications Using H. Pylori Serology and Gastric Ultrasound
Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS
Not yet recruitingAssiut University2302026-04-012026-03-09
Efficacy and Safety of Esomeprazole 40 mg IV in Post-Surgical Patients Admitted to the ICU
Esomeprazole - Stress Ulcers, Reflux Episodes
RecruitingAsian Institute of Gastroenterology, India502026-02-232026-10-05
Compare and Evaluate the Safety and PK Data of a Single Dose Administration of 'AD-115A' or 'AD-1151'
AD-115A, AD-1151 - Gastric Ulcer
Phase 1RecruitingAddpharma Inc.462026-01-272026-02-11
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
Not yet recruitingSibel Seçkin Pehlivan5002025-12-012026-01-02
Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD
Conventional POEM, Sling Fiber-Preserving POEM - Achalasia, Esophageal, GERD (Gastroesophageal Reflux Disease)
Not applicableNot yet recruitingUniversity of California, Irvine1202025-12-012025-10-22
A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)
Sedated gastroscopy - Reflux Esophagitis
RecruitingJilin University602025-12-012026-08-10
Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment
Bismuth, Esomeprazole, Tetracycline - Gastritis, Dyspepsia
Phase 4RecruitingYongquan Shi12482025-10-282025-12-02
A Clinical Trial of Anaprazole for Treating Reflux Esophagitis.
Anaprazole + Rabeprazole placebo, Rabeprazole + Anaprazole placebo - Reflux Esophagitis (RE)
Phase 3RecruitingXuanzhu Biopharmaceutical Co., Ltd.5002025-07-302025-09-29
A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening
Collect epidemiological, diagnostic, and follow-up data after MCG examination. - Gastritis, Gastric Dysplasia
RecruitingNanfang Hospital, Southern Medical University100002025-06-242025-07-04

Showing 20 of 369. Sign in to see all of them.

Narrower conditions

Stomach Ulcer (114)  ·  Esophagitis, Peptic (81)  ·  Duodenal Ulcer (72)  ·  Gastroesophageal Reflux (44)  ·  Stomach Neoplasms (36)  ·  Gastritis (31)  ·  Peptic Ulcer Perforation (21)  ·  Dyspepsia (20)  ·  Zollinger-Ellison Syndrome (16)  ·  Gastrointestinal Hemorrhage (15)  ·  Peptic Ulcer Hemorrhage (13)  ·  Hemorrhage (12)  ·  Esophagitis (8)  ·  Obesity (8)

Broader conditions

Duodenal Diseases (369)  ·  Intestinal Diseases (369)  ·  Digestive System Diseases (367)  ·  Stomach Diseases (365)  ·  Gastrointestinal Diseases (363)  ·  Gastroenteritis (123)  ·  Pathological Conditions, Signs and Symptoms (107)  ·  Esophageal Diseases (100)  ·  Esophagitis (79)  ·  Pathologic Processes (58)  ·  Neoplasms (57)  ·  Signs and Symptoms (55)  ·  Digestive System Neoplasms (53)  ·  Gastrointestinal Neoplasms (51)

Interventions

Esomeprazole (39)  ·  Lansoprazole (39)  ·  Omeprazole (23)  ·  1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (19)  ·  Amoxicillin (18)  ·  Rabeprazole (17)  ·  Clarithromycin (13)  ·  Pantoprazole (13)  ·  Bismuth (11)  ·  Naproxen (9)  ·  Famotidine (8)  ·  Aspirin (7)  ·  Dexlansoprazole (6)  ·  Metronidazole (6)  ·  ilaprazole (6)

Sponsors

AstraZeneca (34)  ·  Takeda (30)  ·  Chinese University of Hong Kong (8)  ·  POZEN (8)  ·  Eisai Co., Ltd. (7)  ·  National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (7)  ·  National Taiwan University Hospital (7)  ·  Xijing Hospital of Digestive Diseases (7)  ·  Assiut University (5)  ·  Boryung Pharmaceutical Co., Ltd (5)  ·  Kaohsiung Veterans General Hospital. (5)  ·  RenJi Hospital (5)  ·  Shanghai Jiao Tong University School of Medicine (5)  ·  Trio Medicines Ltd. (5)  ·  Daewoong Pharmaceutical Co. LTD. (4)

Countries

China (67)  ·  United States (63)  ·  South Korea (48)  ·  Japan (46)  ·  Taiwan (24)  ·  Canada (13)  ·  Egypt (10)  ·  Russia (9)  ·  Italy (8)  ·  United Kingdom (8)  ·  India (7)  ·  France (6)  ·  Germany (6)  ·  Latvia (6)  ·  Turkey (Türkiye) (6)

Top investigators

Shigeru Yoshida, MD (5)  ·  Everardus Orlemans, PhD (4)  ·  Paula Fernstrom (4)  ·  Yongquan Shi, Ph. D (4)  ·  Francis K Chan, MD (3)  ·  Bor-Ru Lin, M.D. (2)  ·  Christopher C. Thompson, MD, MSc (2)  ·  Diansan Su (2)  ·  Francisco M Tercero, MD (2)  ·  Hong Lu (2)

Results publications

PMID 19735233, PMID 20195905, PMID 21129076, PMID 19183157, PMID 19681809, PMID 22607579, PMID 23451835, PMID 24118079, PMID 24119887, PMID 27891632, PMID 28988197, PMID 29196436, PMID 39085080, PMID 12641522, PMID 15645403, PMID 17305763, PMID 17442905, PMID 17767471, PMID 17916545, PMID 18159172, PMID 18407271, PMID 18507843, PMID 19086953, PMID 19210298, PMID 19581810, PMID 20230209, PMID 20379093, PMID 20571304, PMID 20614440, PMID 20679904, PMID 20925534, PMID 21073392, PMID 21144850, PMID 21193359, PMID 21242557, PMID 21319944, PMID 21356058, PMID 21415072, PMID 21442610, PMID 21480935, PMID 21633832, PMID 21726257, PMID 22070512, PMID 22281110, PMID 22369682, PMID 22464259, PMID 22591121, PMID 22631032, PMID 22688850, PMID 23161291

NIH funding

P30CA016672 (2), 2017 (1), 2018 (1), K23DK118179 (1), N01CM62202 (1), R01DK063621 (1), R03DC005917 (1), U01CA062461 (1), U01CA062490 (1)