21 completed, 4 unknown, 1 active not recruiting, 1 recruiting. 11 Phase 1, 6 Phase 3, 5 Phase 2, 2 Not applicable, 2 Phase 4.
Follow Cimetidine: new trials by email Literature Review of Cimetidine trials Research Report on Cimetidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drug Excretion in Breast Milk Cimetidine 200 MG - Postpartum, Lactation | Phase 4 | Recruiting | University of Washington | 50 | 2023-12-04 | 2024-08-06 |
| The Drug-drug Interaction of HSK16149 Capsule With Probenecid Tablets or Cimetidine Tablets in Healthy Subjects HSK16149，probenecid, cimetidine - PHN - Post-Herpetic Neuritis | Phase 1 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 47 | 2023-03-20 | 2023-12-07 |
| Effect of Oral Cimetidine in the Protoporphyrias Cimetidine, Placebo - Erythropoietic Protoporphyria, X-linked Protoporphyria | Phase 2 | Completed | Amy K. Dickey, M.D. | 26 | 2022-06-14 | 2026-09-04 |
| Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters MetFORMIN Oral Solution, Cimetidine 400 MG, Furosemide Oral Liquid Product - Interaction, Endogenous Biomarkers | Early Phase 1 | Completed | Washington State University | 16 | 2022-04-11 | 2025-08-08 |
| Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus)., antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet). - Femoral Neck Fractures, Prosthetic Infection | Phase 3 | Active not recruiting | Umeå University | 7000 | 2022-01-01 | 2026-03-10 |
| Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel Cimetidine, Dexamethasone, Diphenhydramine - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 / Phase 3 | Completed | Ohio State University Comprehensive Cancer Center | 130 | 2021-10-07 | 2025-08-20 |
| Effect of H2 Receptor Antagonist and Proton Pump Inhibitor on the Positivity Rates and Clinical Outcomes of COVID-19 No intervention (Retrospective Cohort Observational) - COVID-19 | Completed | Seoul National University Hospital | 400000 | 2021-05-01 | 2024-11-29 | |
| Drug-drug Interaction Study of Gepotidacin Gepotidacin, Cimetidine, Rifampicin - Infections, Bacterial | Phase 1 | Completed | GlaxoSmithKline | 64 | 2020-08-14 | 2022-03-04 |
| Effect of Cimetidine on the PK of Imeglimin Imeglimin, Cimetidine - Healthy | Phase 1 | Completed | Poxel SA | 16 | 2018-06-19 | 2018-08-27 |
| Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) Microdebrider, Cold-steel surgery (forceps), Carbon dioxide laser - Recurrent Respiratory Papillomatosis, Human Papilloma Virus | Unknown | Newcastle-upon-Tyne Hospitals NHS Trust | 400 | 2018-04-01 | 2022-01-11 | |
| The Efficacy of Cimetidin for Acute - Extrinsic Atopic Dermatitis Treated With Standard Therapy Cimetidine, Placebos - Atopic Dermatitis, Immunoglobulin E Concentration, Serum | Phase 3 | Unknown | Fakultas Kedokteran Universitas Indonesia | 26 | 2018-03-26 | 2019-10-04 |
| Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects Lucerastat, Cimetidine - Healthy Subjects | Phase 1 | Completed | Idorsia Pharmaceuticals Ltd. | 14 | 2018-01-09 | 2022-06-02 |
| This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men Digoxin, Furosemide, Metformin - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 45 | 2017-10-25 | 2023-11-07 |
| Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers Placebo, Cimetidine, BI 1060469 high dose - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 53 | 2014-09-01 | 2014-12-24 |
| Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients Esomeprazole, Cimetidine - Stress Ulcer Prophylaxis | Phase 3 | Completed | AstraZeneca | 343 | 2014-07-01 | 2017-03-10 |
| Drug-drug Interaction Study of CHF5993 With Cimetidine CHF 5993 pMDI, Cimetidine plus CHF5993 pMDI - COPD | Phase 1 | Completed | Chiesi Farmaceutici S.p.A. | 25 | 2014-05-01 | 2021-10-29 |
| High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer Esomeprazole Na, Cimetidine, Esomeprazole Mg - Bleeding Peptic Ulcer | Phase 3 | Completed | AstraZeneca | 239 | 2013-02-01 | 2016-03-08 |
| Dexpramipexole and Cimetidine Drug Drug Interaction (DDI) Dexpramipexole, Cimetidine plus Dexpramipexole - Amyotrophic Lateral Sclerosis | Phase 1 | Completed | Knopp Biosciences | 14 | 2012-03-01 | 2014-11-25 |
| Proton Pump Inhibitors and Risk of Community-acquired Pneumonia esomeprazole, omeprazole, pantoprazole - Gastroesophageal Reflux Disease (GERD), Community-acquired Pneumonia | Completed | Canadian Network for Observational Drug Effect Studies, CNODES | 4238504 | 2011-09-01 | 2015-09-22 | |
| Patient-specific Positioning Guides (PSPG) Technique Versus Conventional Technique in Total Knee Arthroplasty TKR with Positioning Guides (PSPG), TKR with Conventional Technique - Gonarthritis | Not applicable | Unknown | Oslo University Hospital | 109 | 2011-09-01 | 2017-03-29 |
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Femoral Neck Fractures (2) · AIDS-Related Complex (1) · Acquired Immunodeficiency Syndrome (1) · Amyotrophic Lateral Sclerosis (1) · Bacterial Infections (1) · Breast Carcinoma In Situ (1) · Breast Feeding (1) · Breast Neoplasms (1) · COVID-19 (1) · Carcinoma, Renal Cell (1) · Community-Acquired Pneumonia (1) · Cystadenocarcinoma, Serous (1) · Dermatitis, Atopic (1) · Endometrial Neoplasms (1) · Gastroesophageal Reflux (1)
Boehringer Ingelheim (3) · AstraZeneca (2) · University of Maryland, Baltimore (2) · Amy K. Dickey, M.D. (1) · Canadian Network for Observational Drug Effect Studies, CNODES (1) · Chiesi Farmaceutici S.p.A. (1) · Community Research Initiative of New England (1) · Fakultas Kedokteran Universitas Indonesia (1) · GlaxoSmithKline (1) · Haisco Pharmaceutical Group Co., Ltd. (1) · Hoag Memorial Hospital Presbyterian (1) · Idorsia Pharmaceuticals Ltd. (1) · Knopp Biosciences (1) · M.D. Anderson Cancer Center (1) · Newcastle-upon-Tyne Hospitals NHS Trust (1)
United States (12) · China (3) · Germany (3) · Sweden (2) · United Kingdom (2) · Belgium (1) · Canada (1) · Indonesia (1) · Norway (1) · South Korea (1)
Adam Donne (1) · Amy K Dickey, MD (1) · Anuja Jhingran, MD (1) · Finnur Snorrason, MD, PhD (1) · Hilde Apold, MD, PhD (1) · James Polli (1) · James Polli, PhD (1) · Justin van Leeuwen, MD (1) · Karl Anderson, MD (1) · Kristian Filion, PhD (1) · Marie-Laure Boof, PhD (1) · Mary Hebert, PharmD, FCCP (1)
PMID 23385150, PMID 23856153, PMID 26581750, PMID 27209586, PMID 29638148, PMID 31836927, PMID 35175572, PMID 39445512, PMID 40401788
2014 (1), 2017 (1), R01HD081299 (1), R01HD112282 (1)