4 recruiting, 4 unknown, 3 completed, 2 not yet recruiting. 13 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Recruiting 4, Unknown 4, Completed 3, Not yet recruiting 2 |
Follow Esketamine: new trials by email Literature Review of Esketamine trials Research Report on Esketamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients Dexmedetomidine-Esketamine Combination, Dexmedetomidine - Aged, Intensive Care Units | Not applicable | Not yet recruiting | Peking University First Hospital | 1508 | 2025-11-01 | 2025-07-31 |
| The Efficacy and Safety of Short Term S-ketamine Infusion as an Adjunctive Therapy in Patients With Fibromyalgia Pregabalin and venlafaxine concomitant therapy, Esketamine plus pregabalin and venlafaxine concomitant therapy - Fibromyalgia, Pregabalin | Not applicable | Recruiting | Beijing Tiantan Hospital | 92 | 2025-09-15 | 2026-05-07 |
| Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children Etomidate and fentanyl group, Etomidate and esketamine group - Etomidate, Esketamine | Not applicable | Not yet recruiting | Anqing Municipal Hospital | 64 | 2025-07-10 | 2025-07-14 |
| Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation remimazolam group, dexmedetomidine group, esketamine group - Remimazolam, Dexmedetomidine | Not applicable | Recruiting | Maternal and Child Health Hospital of Hubei Province | 150 | 2025-04-01 | 2025-07-10 |
| Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT) Esketamine, Normal saline - Delirium in Old Age, Delirium, Postoperative | Not applicable | Recruiting | Nanfang Hospital, Southern Medical University | 1670 | 2025-02-12 | 2025-04-27 |
| Effect of Subanesthetic Dose of Esketamine on Sleep Quality Esketamine at low dose, Normal Saline (0.9% NaCl) - Insomnia, Breast Cancer Surgery | Not applicable | Recruiting | Nanjing First Hospital, Nanjing Medical University | 184 | 2024-12-30 | 2025-02-10 |
| Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease esketamine, normal Saline - PD - Parkinson's Disease, Deep Brain Stimulation | Not applicable | Unknown | Beijing Tiantan Hospital | 102 | 2024-08-09 | 2024-08-09 |
| Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery Esketamine, normal saline - Anxiety State, Esketamine | Not applicable | Completed | Zhejiang Cancer Hospital | 185 | 2024-08-05 | 2025-09-16 |
| Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery Esketamine, saline - Esketamine, Sleep Disturbance | Not applicable | Unknown | Beijing Tiantan Hospital | 156 | 2024-06-10 | 2025-01-24 |
| Effect of Esketamine on Conscious State in Patients With pDoC Esketamine, normal saline - Esketamine, Consciousness Disorders | Not applicable | Unknown | Beijing Tiantan Hospital | 116 | 2024-05-20 | 2024-07-30 |
| Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation Dexmedetomidine-esketamine combination, Remifentanil, Oxycodone - Liver Cancer, Radiofrequency Ablation | Not applicable | Completed | Peking University First Hospital | 88 | 2023-10-16 | 2025-04-02 |
| Median Effective Dose of Esketamine Pretreatment to Prevent Sufentanil-induced Cough Esketamine - Sufentanil, Esketamine | Not applicable | Unknown | Yangzhou University | 30 | 2023-04-01 | 2023-04-12 |
| Esketamine on Postpartum Depression in Cesarean Section Women Esketamine, Normal saline - Esketamine, Postpartum Depression | Not applicable | Completed | Ailin Luo | 336 | 2021-05-01 | 2024-08-06 |
Delirium (2) · Anxiety Disorders (1) · Cognitive Dysfunction (1) · Consciousness Disorders (1) · Depression, Postpartum (1) · Emergence Delirium (1) · Fibromyalgia (1) · Liver Neoplasms (1) · Pain, Postoperative (1) · Parasomnias (1) · Parkinson Disease (1) · Sleep Initiation and Maintenance Disorders (1)
Mental Disorders (7) · Nervous System Diseases (7) · Neurobehavioral Manifestations (3) · Neurocognitive Disorders (3) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Confusion (2) · Sleep Wake Disorders (2) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cognition Disorders (1) · Depressive Disorder (1) · Digestive System Diseases (1)
Esketamine (9) · Saline Solution (6) · Dexmedetomidine (2) · Control Groups (1) · Etomidate (1) · Oxycodone (1) · Pregabalin (1) · Remifentanil (1) · Sodium Chloride (1) · remimazolam (1)
Beijing Tiantan Hospital (4) · Peking University First Hospital (2) · Ailin Luo (1) · Anqing Municipal Hospital (1) · Maternal and Child Health Hospital of Hubei Province (1) · Nanfang Hospital, Southern Medical University (1) · Nanjing First Hospital, Nanjing Medical University (1) · Yangzhou University (1) · Zhejiang Cancer Hospital (1)
China (11)
Dong-Xin Wang, MD, PhD (2) · Ke-Xuan Liu, MD (1) · Na Li NaLi, MD (1) · Ruquan Han, MD,PhD (1)
PMID 14982564, PMID 23982301, PMID 24650832, PMID 32733363, PMID 33022440, PMID 33189715, PMID 33387333, PMID 34970147, PMID 34992482, PMID 36454569, PMID 40037679, PMID 41607308, PMID 42170615