609 completed, 144 unknown, 130 recruiting, 64 not yet recruiting. 584 Not applicable, 104 Phase 2, 80 Phase 3, 64 Phase 4, 33 Phase 1.
Follow Parasomnias: new trials by email Literature Review of Parasomnias trials Research Report on Parasomnias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuromodulation to Overcome Severe Restless Legs Syndrome Spinal Cord Stimulation - Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS) | Not applicable | Not yet recruiting | Marshall Holland | 15 | 2027-10-01 | 2026-10-09 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| Efficacy of Sleep Hygiene Intervention in Elderly With Insomnia Sleep hygiene - Eelderly With Sleep Disturbances | Not applicable | Not yet recruiting | University of Pittsburgh | 100 | 2027-02-01 | 2026-03-27 |
| Talk Parenting Education Program II The Talk Parenting Program - Parenting Practices, Self Efficacy | Not applicable | Not yet recruiting | Oregon Research Behavioral Intervention Strategies, Inc. | 184 | 2026-11-01 | 2026-10-05 |
| Tolerability and Efficacy of CBD Extract for RLS Treatment BRC-002, Placecbo - Restless Leg Syndrome | Phase 2 | Not yet recruiting | University of Colorado, Denver | 60 | 2026-11-01 | 2026-10-08 |
| A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2) Berobenatide, Placebo - Apnea, Sleep Disorders | Phase 3 | Not yet recruiting | Pfizer | 258 | 2026-10-19 | 2026-10-19 |
| The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps Magnesium and melatonin based multi-ingredient dietary supplementation, Placebo - Poor Sleep Quality, Leg Cramps, Nocturnal | Not applicable | Recruiting | StudySetGo | 50 | 2026-10-10 | 2026-10-14 |
| Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation - Sleep Disturbance, Sleep Problems | Not applicable | Not yet recruiting | Universidad Pública de Navarra | 250 | 2026-10-09 | 2026-10-08 |
| Sleep in Children Placed in Out-of-home Care Sleep and Adjustment in Foster care Environments (SAFE) intervention, Sleep Education Support - Sleep Problems, Parasomnias | Not applicable | Not yet recruiting | Vrije Universiteit Brussel | 730 | 2026-10-01 | 2026-09-15 |
| eMindExCare for Prostate Cancer Patients Undergoing Active Treatment eMindExCare, Enhanced Health Education - Prostate Cancer, Sleep Disturbance | Not applicable | Not yet recruiting | The University of Hong Kong | 60 | 2026-10-01 | 2026-07-29 |
| Massage, Sleep , and Pain Semi-Standardized Integrative Therapeutic Massage, Usual Care - Chronic Musculoskeletal Pain, Sleep Disturbances | Not applicable | Not yet recruiting | Defense and Veterans Center for Integrative Pain Management | 120 | 2026-10-01 | 2026-08-24 |
| Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy - Spinal Cord Injuries (SCI), Chronic Pain | Not applicable | Not yet recruiting | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 40 | 2026-10-01 | 2026-09-29 |
| Mentalization and Social Cognition in Adolescents After Suicide Attempt Test, Questionnaires - Violent Suicide Attempts in Adolescents | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 82 | 2026-10-01 | 2026-09-18 |
| Acoustic Stimulation to Study and Modulate Sleepwalking and Related Arousal Disorders Closed-Loop/Open-Loop Acoustic Stimulation (CLAS) - NREM Parasomnias, Sleepwalking | Not applicable | Not yet recruiting | Anna Castelnovo | 50 | 2026-10-01 | 2026-08-10 |
| Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study Smartwatch and phone app - Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD) | Not yet recruiting | Queen Mary University of London | 60 | 2026-10-01 | 2026-10-02 | |
| Efficacy and Safety of Super High-Flux Hemodialysis in Maintenance Dialysis Patients. SHINE-RLS (Super High-flux Dialysis Improves Neuro-symptoms and Efficacy in Restless Legs Syndrome) Super High-Flux HD - End Stage Renal Failure, Hemodialysis, Restless Leg Syndrome (RLS) | Not applicable | Not yet recruiting | Far Eastern Memorial Hospital | 40 | 2026-10-01 | 2026-08-31 |
| Intravenous Iron in the Management of Drug-resistant Restless Legs syndromeI Ferric Carboxymaltose Injection [Ferinject], Randomization, Questionnaire and Physical Exam - Restless Legs Syndrome (RLS) | Phase 2 | Not yet recruiting | University Hospital, Montpellier | 66 | 2026-10-01 | 2026-09-16 |
| Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Bao Yuan Tang full-component extract 2.0g plus a placebo consisting of maltodextrin 2.0g, Galactooligosaccharides 2.0g - Sleep Disturbance, Fatigue Syndrome, Chronic | Not applicable | Not yet recruiting | Hepatopancreatobiliary Surgery Institute of Gansu Province | 400 | 2026-09-30 | 2026-08-19 |
| Pilot Trial for Health Products on Mood and Sleep Quality Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF), Placebo - Sleep Disturbance, Emotional Disturbance | Not applicable | Recruiting | The University of Hong Kong | 60 | 2026-09-22 | 2026-10-02 |
| Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4 Sleep Disturbance, Cognitive Change | Recruiting | Chang Gung Memorial Hospital | 250 | 2026-09-15 | 2026-07-30 |
Showing 20 of 1078. Sign in to see all of them.
Restless Legs Syndrome (251) · Sleep Initiation and Maintenance Disorders (165) · REM Sleep Behavior Disorder (101) · Anxiety Disorders (83) · Sleep Wake Disorders (81) · Depression (74) · Parkinson Disease (73) · Fatigue (70) · Sleep Bruxism (62) · Pain (50) · Stress Disorders, Post-Traumatic (26) · Alzheimer Disease (25) · Sleep Apnea Syndromes (25) · Sleep Apnea, Obstructive (24)
Nervous System Diseases (1076) · Mental Disorders (1067) · Sleep Wake Disorders (997) · Dyssomnias (444) · Sleep Disorders, Intrinsic (430) · Pathological Conditions, Signs and Symptoms (351) · Signs and Symptoms (294) · Neurologic Manifestations (227) · Behavior (185) · Central Nervous System Diseases (149) · Brain Diseases (141) · Behavioral Symptoms (105) · Neurodegenerative Diseases (102) · REM Sleep Parasomnias (101)
Cognitive Behavioral Therapy (25) · Melatonin (25) · Pramipexole (20) · 1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid (18) · Surveys and Questionnaires (17) · rotigotine (16) · ropinirole (15) · Polysomnography (12) · Exercise (11) · Gabapentin (10) · Saline Solution (9) · Therapeutics (9) · Occlusal Splints (8) · Sugars (8) · Phototherapy (7)
Chinese University of Hong Kong (25) · Boehringer Ingelheim (20) · GlaxoSmithKline (17) · XenoPort, Inc. (14) · Johns Hopkins University (13) · University of Pittsburgh (13) · Massachusetts General Hospital (11) · University Hospital, Montpellier (11) · UCB Pharma (10) · Cairo University (9) · Noctrix Health, Inc. (9) · Assistance Publique - Hôpitaux de Paris (8) · Seoul National University Hospital (8) · Stanford University (8) · University of Arizona (8)
United States (431) · Turkey (Türkiye) (74) · France (51) · Canada (48) · Germany (40) · China (36) · United Kingdom (35) · Hong Kong (33) · Italy (31) · Taiwan (31) · Switzerland (28) · Spain (23) · Denmark (22) · Sweden (21) · Brazil (19)
Jonathan D Charlesworth, PhD (7) · Jihui Zhang, PhD (4) · John W Winkelman, MD, PhD (4) · Yun Kwok Wing, MBChB (4) · Yun Kwok Wing, Professor (4) · Amy G Hartman, PhD (3) · Birna Baldursdottir, PhD (3) · Bradley Boeve, MD (3)
PMID 2748771, PMID 26788345, PMID 27067343, PMID 27288210, PMID 11556271, PMID 16717171, PMID 21256799, PMID 21527006, PMID 23600892, PMID 24634631, PMID 24843394, PMID 25386668, PMID 26212172, PMID 26446245, PMID 33189083, PMID 36000763, PMID 36907376, PMID 39198005, PMID 39436396, PMID 41914053, PMID 10214756, PMID 10406987, PMID 10527042, PMID 10668003, PMID 10853813, PMID 10979878, PMID 11076832, PMID 11400186, PMID 11704164, PMID 11706956, PMID 11724917, PMID 12498954, PMID 12804680, PMID 12841373, PMID 12904089, PMID 12964174, PMID 12970021, PMID 14592339, PMID 14592341, PMID 14592342, PMID 14998254, PMID 15175402, PMID 15345186, PMID 15645531, PMID 15779234, PMID 16025231, PMID 16052775, PMID 16106717, PMID 16442563, PMID 16541841
2025 (4), 2005 (2), 2019 (2), P30AG064198 (2), R34MH132724 (2), R44NS117294 (2), 1UG3NS145980-01 (1), 2009 (1), 2014 (1), 2017 (1), 2018 (1), 2023 (1), 3UG1CA189824-04S1 (1), D43TW009114 (1), I01CX002591 (1)