40 completed, 23 recruiting, 18 unknown, 13 not yet recruiting. 64 Not applicable, 7 Phase 4, 2 Phase 1, 2 Phase 3.
Follow Atrioventricular Block: new trials by email Literature Review of Atrioventricular Block trials Research Report on Atrioventricular Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG digital single-channel ECG recording - Atrial Fibrillation, Atrioventricular Block, Second and Third Degree | Not yet recruiting | I.M. Sechenov First Moscow State Medical University | 300 | 2026-12-31 | 2026-02-10 | |
| Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP) - Bradycardia, Atrioventricular Block | Not applicable | Not yet recruiting | Yonsei University | 300 | 2026-10-01 | 2026-09-04 |
| Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in Japan Application of ambulatory cardiac monitor - Atrial Fibrillation (AF), Atrial Flutter | Not applicable | Not yet recruiting | iRhythm Technologies, Inc. | 130 | 2026-09-30 | 2026-10-19 |
| Transjugular Approach for Implantation of Active Fixation Leadless Pacemakers Aveir VR Leadless Pacemaker - Bradycardia, Heart Block | Not applicable | Not yet recruiting | Min Shen | 15 | 2026-09-10 | 2026-09-03 |
| OPTImizing Lead Placement in Patients Requiring Pacemaker After Cardiac Surgery Left bundle branch area pacing, Conventional pacing strategy - Atrioventricular Block, Cardiac Surgery | Not applicable | Not yet recruiting | Sahlgrenska University Hospital | 110 | 2026-09-10 | 2026-08-31 |
| SPIKE FLOW Endocardial Lead Safety and Performance Study Lead insertion, lead removal - Acute Myocardial Infarction (AMI), Asystole | Not applicable | Recruiting | FIAB SpA | 131 | 2026-08-07 | 2026-10-20 |
| ALPs Single ChambEr New Device Leadless ventricular pacemaker implantation - Bradycardia, Brady-tachy Syndrome | Not applicable | Not yet recruiting | Cairdac SA | 10 | 2026-06-01 | 2026-03-10 |
| ALPs Single ChambEr New Device Study Leadless ventricular pacemaker implantation - Brady-tachy Syndrome, Brady Arrythmia | Not applicable | Not yet recruiting | Cairdac SA | 15 | 2026-06-01 | 2026-03-18 |
| BIO|STREAM.CSP CLS Left bundle branch area pacing with Closed Loop Stimulation - Sinus Node Disease, Atrioventricular Block | Recruiting | Biotronik SE & Co. KG | 150 | 2026-05-29 | 2026-07-17 | |
| BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System LivIQ Leadless Pacemaker System - Leadless Pacemaker, Bradycardia | Not applicable | Recruiting | Biotronik, Inc. | 325 | 2026-03-16 | 2026-10-16 |
| Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEF Right Ventricular Pacing, Left Bundle Branch Pacing - Atrial Fibrillation (AF), Pacemaker Therapy | Not applicable | Recruiting | University Hospital of Patras | 244 | 2026-02-05 | 2026-03-13 |
| LLL vs. SDL for LBBP: A Non-inferiority RCT SDL implantation, LLL implantation - Bradycardia, Conduction Block, Atrioventricular | Not applicable | Not yet recruiting | Ningbo No.2 Hospital | 288 | 2026-01-24 | 2026-02-03 |
| Efficacy and Safety of Micra AV2 Transcatheter Pacing System Implant procedure of a Micra AV2 leadless pacemaker (Medtronic) - AV Block Complete, AV Block-2Nd Degree-Type 1 | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 150 | 2026-01-12 | 2026-01-21 |
| Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up Pacemaker lead - Bradycardia, Atrioventricular Block | Active not recruiting | Boston Scientific Corporation | 140 | 2025-12-19 | 2026-10-27 | |
| RandomIsed sTudy of Physiologic cArdiac stimuLation in patIents With Atrio-ventricular Conduction Disease Conduction System Pacing (CSP), Right Ventricular (RV) Pacing - Atrioventricular Block | Not applicable | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 1260 | 2025-12-03 | 2026-05-27 |
| PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation Atrial Fibrillation, Sick Sinus Syndrome | Not yet recruiting | Ilya Lukin | 500 | 2025-12-01 | 2025-12-12 | |
| Central Haemodynamics and Pacing for AV Block Right ventricular pacing, Conduction system pacing - Atrioventricular Block, Pacing Therapy | Not applicable | Recruiting | University of Tartu | 124 | 2025-11-28 | 2026-03-09 |
| Trial Evaluating the Benefit of Left Bundle Branch Area Stimulation Compared With Conventional Pacing in Post-TAVI Atrioventricular Atrioventricular Block Pacemaker implantation using left bundle branch area stimulation, Right ventricular pacemaker implantation - Atrioventricular Block, Pacemaker | Not applicable | Recruiting | Nantes University Hospital | 266 | 2025-11-25 | 2026-04-15 |
| Impact of Atrioventricular Delay Optimization on Ventricular Function in Conduction System Pacing Echocardiography-Guided Atrioventricular Delay Optimization - Atrioventricular Block, Conduction System Pacing | Not applicable | Completed | Bursa Yuksek Ihtisas Training and Research Hospital | 39 | 2025-10-06 | 2026-06-08 |
| The CT-verified Data Collection Study to Investigate the Correlation Between the Leadless Pacemaker Tip Location and Echo, ECG Observational - Bradycardia Sinus, AV Block | Active not recruiting | Medtronic Cardiac Rhythm and Heart Failure | 40 | 2025-06-17 | 2026-05-01 |
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Bradycardia (34) · Sick Sinus Syndrome (23) · Arrhythmias, Cardiac (18) · Heart Failure (18) · Atrial Fibrillation (16) · Bundle-Branch Block (12) · Syncope, Vasovagal (7) · Neoplasm Metastasis (6) · Tachycardia, Ventricular (6) · Ventricular Dysfunction (5) · Atrial Flutter (4) · Heart Diseases (4) · Ventricular Fibrillation (4) · Aortic Valve Stenosis (3)
Cardiac Conduction System Disease (112) · Pathologic Processes (112) · Pathological Conditions, Signs and Symptoms (112) · Cardiovascular Diseases (109) · Heart Block (109) · Heart Diseases (108) · Arrhythmias, Cardiac (94) · Arrhythmia, Sinus (23) · Nervous System Diseases (12) · Consciousness Disorders (9) · Neurobehavioral Manifestations (9) · Neurologic Manifestations (9) · Signs and Symptoms (9) · Unconsciousness (9) · Autonomic Nervous System Diseases (8)
Cardiac Resynchronization Therapy (5) · Device Lead Extraction (2) · Transcatheter Aortic Valve Replacement (2) · Adenosine (1) · Cardiac Catheterization (1) · Catheter Ablation (1) · Catheterization, Peripheral (1) · Defibrillators (1) · Dexamethasone (1) · Immunoglobulins, Intravenous (1) · Pacemaker, Artificial (1) · Watchful Waiting (1)
Abbott Medical Devices (7) · Medtronic Cardiac Rhythm and Heart Failure (6) · BackBeat Medical Inc (4) · Biotronik, Inc. (3) · Boston Scientific Corporation (3) · Aalborg University Hospital (2) · Aarhus University Hospital Skejby (2) · Cairdac SA (2) · Fu Wai Hospital, Beijing, China (2) · Germans Trias i Pujol Hospital (2) · Hospital Clinic of Barcelona (2) · Institut für Pharmakologie und Präventive Medizin (2) · Korea University (2) · LivaNova (2) · Medical University of Silesia (2)
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PMID 15670960, PMID 21712276, PMID 34387126, PMID 17367361, PMID 21857020, PMID 22182495, PMID 22275485, PMID 23614585, PMID 24347317, PMID 24509688, PMID 25380704, PMID 25697851, PMID 25980618, PMID 26411271, PMID 26551877, PMID 27151347, PMID 27402231, PMID 28160481, PMID 28450351, PMID 28496712, PMID 29173611, PMID 29275370, PMID 29535066, PMID 29628351, PMID 29758405, PMID 29759475, PMID 30338504, PMID 30462207, PMID 30704273, PMID 30704289, PMID 31314822, PMID 31330187, PMID 31709982, PMID 32188285, PMID 32591894, PMID 32717315, PMID 33496721, PMID 33928713, PMID 34036145, PMID 34192953, PMID 34255038, PMID 34307499, PMID 34465122, PMID 34900053, PMID 35221255, PMID 36075532, PMID 36113707, PMID 36114133, PMID 36700426, PMID 36750275
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