20 completed, 13 unknown, 11 recruiting, 3 not yet recruiting. 13 Not applicable, 3 Phase 2, 3 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Completed 6, Unknown 5, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Terminated 2, Withdrawn 1 |
| Phase 4 | 1 | Completed 1 |
Follow Brugada Syndrome: new trials by email Literature Review of Brugada Syndrome trials Research Report on Brugada Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome Brugada Syndrome (BrS), Ventricular Arrhythmia | Recruiting | Hospital Clinic of Barcelona | 200 | 2026-07-15 | 2026-09-08 | |
| Analysis of the Presence and Cardiac Functional Effects of Anti-NaV1.5 Autoantibodies in Patients With Metastatic Tumors ECG - Brugada Syndrome (BrS), Breast Cancer Females | Not applicable | Not yet recruiting | IRCCS Policlinico S. Donato | 196 | 2026-01-01 | 2026-01-23 |
| Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada Syndrome Empagliflozin (EMPA) - Brugada Syndrome (BrS) | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 10 | 2025-09-15 | 2025-09-12 |
| DNA Methylation in Brugada Syndrome and Risk of Sudden Cardiac Death Brugada Syndrome, Sudden Cardiac Death Due to Cardiac Arrhythmia | Not yet recruiting | University of Campania Luigi Vanvitelli | 10 | 2025-05-01 | 2025-03-24 | |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| GenLab: Unveiling the Genetic Landscape of Brugada Syndrome: Novel Biomarker Discovery for Precise Diagnosis Brugada Syndrome (BrS) | Recruiting | IRCCS Policlinico S. Donato | 350 | 2024-12-02 | 2025-05-14 | |
| Unmasking Concealed Arrhythmia Syndromes 12-lead ECG, Continuous long term ambulatory ECG monitoring, Ultra-high-frequency ECG - Brugada ECG Patterns, Brugada Syndrome (BrS) | Recruiting | Imperial College London | 200 | 2024-09-09 | 2025-05-23 | |
| Brugada Syndrome Substrate Characterization and Ablation ablation - Brugada Syndrome | Not applicable | Recruiting | Maria Cecilia Hospital | 20 | 2023-02-01 | 2025-08-15 |
| Impact on Risk Stratification of Overlap Syndrome Phenotype in Patients With E1784K Mutation in SCN5A Long QT Syndrome, Brugada Syndrome | Completed | Centre Hospitalier Universitaire de la Réunion | 47 | 2022-04-05 | 2025-08-05 | |
| Drug-induced Brugada Syndrome Research Database Brugada Syndrome, Arrhythmia | Unknown | University of Campania Luigi Vanvitelli | 500 | 2021-09-07 | 2021-09-17 | |
| European Perioperative Brugada Survey Survey - Brugada Syndrome | Not applicable | Unknown | Universitair Ziekenhuis Brussel | 300 | 2021-03-31 | 2021-11-09 |
| Clinical Cohort Study - TRUST Arrhythmias, Cardiac, Atrial Fibrillation | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 5000 | 2021-03-17 | 2025-03-30 | |
| Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations MRI - Long QT Syndrome, Brugada Syndrome | Not applicable | Completed | University Hospital, Montpellier | 214 | 2021-02-01 | 2026-06-18 |
| Brugada Syndrome and Artificial Intelligence Applications to Diagnosis Patients affected by Brugada Syndrome 1 - Brugada Syndrome 1 | Not applicable | Unknown | Istituto di Fisiologia Clinica CNR | 144 | 2021-01-15 | 2020-11-24 |
| Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial Ajmaline - Brugada Syndrome, Channelopathies | Unknown | Universitair Ziekenhuis Brussel | 25 | 2020-11-16 | 2021-12-08 | |
| Epicardial Radiofrequency Catheter Ablation in Patients With Brugada Syndrome Radiofrequency catheter ablation, Sham procedure - Brugada Syndrome | Not applicable | Completed | University of Sao Paulo General Hospital | 20 | 2020-11-03 | 2026-05-28 |
| Physical Activity in Children With Inherited Cardiac Diseases Long QT Syndrome, Brugada Syndrome | Completed | University Hospital, Montpellier | 28 | 2020-05-01 | 2022-05-26 | |
| Artificial Intelligence for the Prioritization of Genetic Background in Brugada Syndrome Brugada Syndrome | Completed | IRCCS San Raffaele | 200 | 2018-12-19 | 2024-04-19 | |
| The Conus Brugada Syndrome Study Brugada Syndrome | Completed | Barts & The London NHS Trust | 3 | 2018-11-05 | 2024-10-22 | |
| Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum Mapping Endocardial mapping - Brugada Syndrome Type 1 | Not applicable | Unknown | Hospices Civils de Lyon | 10 | 2018-07-01 | 2018-06-28 |
Showing 20 of 51. Sign in to see all of them.
Long QT Syndrome (12) · Arrhythmogenic Right Ventricular Dysplasia (9) · Arrhythmias, Cardiac (7) · Polymorphic Catecholaminergic Ventricular Tachycardia (7) · Cardiomyopathy, Hypertrophic (5) · Cardiomyopathy, Dilated (4) · Death, Sudden (4) · Atrial Fibrillation (3) · Channelopathies (3) · Death, Sudden, Cardiac (3) · Short Qt Syndrome (3) · Tachycardia, Ventricular (3) · Cardiomyopathy, Restrictive (2) · Death (2)
Cardiovascular Diseases (51) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (51) · Genetic Diseases, Inborn (51) · Heart Diseases (51) · Cardiac Conduction System Disease (50) · Arrhythmias, Cardiac (44) · Pathologic Processes (24) · Pathological Conditions, Signs and Symptoms (24) · Cardiovascular Abnormalities (14) · Congenital Abnormalities (13) · Heart Defects, Congenital (13) · Cardiomyopathies (10) · Tachycardia (9) · Death (8) · Tachycardia, Ventricular (6)
Catheter Ablation (5) · Ajmaline (4) · Electrocardiography (2) · Blood Specimen Collection (1) · Defibrillators, Implantable (1) · Echocardiography (1) · Exome (1) · Flecainide (1) · Lorajmine (1) · Prajmaline (1) · Procainamide (1) · Quinidine (1) · Radiofrequency Ablation (1) · Sugars (1) · Surveys and Questionnaires (1)
Universitair Ziekenhuis Brussel (6) · IRCCS Policlinico S. Donato (5) · Pacific Rim Electrophysiology Research Institute (3) · Hospital Clinic of Barcelona (2) · Imperial College London (2) · NYU Langone Health (2) · Nantes University Hospital (2) · University Hospital, Montpellier (2) · University of British Columbia (2) · University of Campania Luigi Vanvitelli (2) · University of Sao Paulo General Hospital (2) · Abbott Medical Devices (1) · Assistance Publique - Hôpitaux de Paris (1) · Barts & The London NHS Trust (1) · Centre Hospitalier Universitaire de la Réunion (1)
Italy (11) · France (7) · Belgium (6) · United Kingdom (6) · United States (5) · Brazil (4) · Germany (4) · Thailand (4) · Netherlands (3) · Spain (3) · Canada (2) · China (1) · Denmark (1) · Israel (1) · Japan (1)
Carlo Pappone, MD (3) · Koonlawee Nademanee, MD (3) · A Amiel, Dr (1) · A Leenhardt, Pr (1) · Ana CG Oliveira, S (1) · Andreas Barth, MD (1) · Andreas Metzner, MD (1) · Andreas Rillig, MD (1) · Andrew D Krahn, Dr. (1) · Andrew D Krahn, MD (1) · Angeliki Asimaki (1) · Apichai Khongphatthanayothin, MD (1) · Cesar J Gruppi, PhD (1) · Chiara Di Resta, PhD (1) · D Babuty, Pr (1)
PMID 21403098, PMID 29650119, PMID 31647530, PMID 1309182, PMID 16203906, PMID 19597050, PMID 21816308, PMID 21955300, PMID 22294707, PMID 22944906, PMID 23872634, PMID 24011539, PMID 26291334, PMID 26516000, PMID 26783233, PMID 27544747, PMID 27635072, PMID 27979714, PMID 28500178, PMID 28600387, PMID 30067493, PMID 31319747, PMID 32619740, PMID 33512057, PMID 33960826, PMID 34092119, PMID 34645390, PMID 34693720, PMID 36960730, PMID 37638409, PMID 39998828, PMID 40810874, PMID 41229453, PMID 41732243, PMID 9355899
2016 (1), R01HL128743 (1), R01HL143485 (1)