204 completed, 108 recruiting, 96 unknown, 46 active not recruiting. 77 Not applicable, 52 Phase 3, 43 Phase 2, 6 Phase 1, 5 Early Phase 1.
Follow Watchful Waiting: new trials by email Literature Review of Watchful Waiting trials Research Report on Watchful Waiting
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial Atezolizumab, Atezolizumab and Recombinant Human Hyaluronidase, Biospecimen Collection - Lung Non-Small Cell Carcinoma | Phase 3 | Recruiting | National Cancer Institute (NCI) | 336 | 2027-03-02 | 2026-10-29 |
| Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain Biospecimen Collection, Low-Dose Aspirin, Patient Observation - Endometrial Carcinoma | Phase 4 | Not yet recruiting | Mayo Clinic | 20 | 2027-02-12 | 2026-08-05 |
| Testing the Investigational Medication Pembrolizumab After Kidney Removal for Patients With Non-Clear Cell Renal Cell Carcinoma Biospecimen Collection, Bone Scan, Computed Tomography - Non-Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 | Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 400 | 2027-02-10 | 2026-07-08 |
| Comparing Radiation After Surgery to Observation After Surgery in Patients With Clinical Low-Risk, Molecular High-Risk Meningioma, and Evaluating Observation After Surgery in Patients With Clinical and Molecular Low-Risk Meningioma Patient Observation, Magnetic Resonance Imaging, Biospecimen Collection - Grade 1 Meningioma, Grade 2 Meningioma | Phase 3 | Not yet recruiting | NRG Oncology | 464 | 2027-01-28 | 2026-08-25 |
| C2001P-CS3: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIV HPV DNA Testing (Abbott Alinity m HPV Assay), Visual Inspection with Acetic Acid, Cervical Histology (Biopsy Procedures) - Human Papillomavirus (HPV), HPV Associated Cancers | Not applicable | Not yet recruiting | University of California, San Diego | 750 | 2026-11-30 | 2026-10-29 |
| Titanium Particle Release Across Non-Surgical Peri-implantitis Therapies Mechanical Debridement with Titanium Curettes, Mechanical Debridement with Plastic Curettes, 940 nm Diode Laser Decontamination - Peri-implantitis | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 70 | 2026-10-15 | 2026-09-10 |
| A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants Observational, Non-Interventional Study - Muscle Soreness | Not yet recruiting | Reckitt Benckiser Healthcare (UK) Limited | 600 | 2026-10-11 | 2026-10-16 | |
| Long-Term Follow-Up Study of Gamgertamig Observational - Autoimmune Cytopenias | Not yet recruiting | Lakefront Biotherapeutics West LLC | 100 | 2026-10-01 | 2026-09-29 | |
| Comparing Surgical and Nonsurgical Outcomes of Cubital Tunnel Syndrome Cubital tunnel release, Conservative Arm - Cubital Tunnel Syndrome | Not applicable | Not yet recruiting | University of Pittsburgh | 220 | 2026-10-01 | 2026-10-20 |
| Adjuvant Trial in Pancreatic Neuroendocrine Tumors Adjuvant chemotherapy with Capecitabine-Temozolomide, Active surveillance - Pancreatic Neuroendocrine Tumors (pNET), Pancreatic Neuroendocrine Tumors | Phase 3 | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 300 | 2026-09-01 | 2026-05-15 |
| WATER IV PCa (AS Sub-study) Aquablation Therapy, Active Surveillance - Localized Prostate Cancer | Not applicable | Not yet recruiting | PROCEPT BioRobotics | 333 | 2026-09-01 | 2026-08-04 |
| Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION) Active Surveillance With ctHPVDNA (NavDx®) - Squamous Cell Carcinoma, Human Papilloma Virus (HPV) | Phase 2 | Recruiting | Medical University of South Carolina | 36 | 2026-08-12 | 2026-09-14 |
| Active Surveillance Versus Adjuvant Intravesical Chemotherapy in Liquid Biopsy-Defined Low-Shedding Intermediate-Risk NMIBC Active Surveillance, Adjuvant Intravesical Chemotherapy - Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC) | Not applicable | Recruiting | Tianjin Medical University Second Hospital | 670 | 2026-08-10 | 2026-10-09 |
| Respiratory and Exercise Responses by Body Roundness Index in Obesity Observational - Obesity | Not yet recruiting | Biruni University | 120 | 2026-06-20 | 2026-05-19 | |
| Active Surveillance vs Adjuvant Chemoradiotherapy for Locally Resected Intermediate-Risk T1 Rectal Cancer Active surveillance, Adjuvant chemoradiotherapy - Rectal Cancer | Not applicable | Recruiting | Medical University of Gdansk | 480 | 2026-06-14 | 2026-06-25 |
| Artificial Intelligence-assisted MDS-UPDRS Assessment for Parkinson's Disease Observational - Parkinson Disease | Recruiting | Hong Kong University of Science and Technology | 500 | 2026-06-01 | 2026-07-08 | |
| Is Prolonged Systemic Immunotherapy Necessary After Achieving Tumor-free Status in Patients With Extensive Transurethrally Unresectable Very-high-risk NMIBC? Active Surveillance, PD-1/PD-L1 Inhibitor-Based Systemic Immunotherapy - Bladder (Urothelial, Transitional Cell) Cancer, Non Muscle Invasive Bladder Cancer | Phase 2 | Recruiting | Tianjin Medical University Second Hospital | 120 | 2026-05-30 | 2026-10-15 |
| TDAP in Burn Patients (Group 2) Observational Cohort (No Intervention) - Sepsis, Burn Injury | Not yet recruiting | Henry M. Jackson Foundation for the Advancement of Military Medicine | 80 | 2026-05-15 | 2026-02-04 | |
| Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1 Observational Cohort (No Intervention) - Sepsis, Burn Injury | Not yet recruiting | Henry M. Jackson Foundation for the Advancement of Military Medicine | 40 | 2026-05-15 | 2026-02-04 |
Showing 20 of 538. Sign in to see all of them.
Prostatic Neoplasms (26) · Breast Neoplasms (13) · COVID-19 (13) · Carcinoma, Non-Small-Cell Lung (13) · Neoplasms (13) · Obesity (11) · Colonic Neoplasms (9) · Diabetes Mellitus, Type 2 (8) · Motor Activity (8) · Pulmonary Disease, Chronic Obstructive (8) · Cardiovascular Diseases (7) · Heart Failure (7) · Uterine Cervical Neoplasms (7) · Carcinoma, Renal Cell (6) · Colorectal Neoplasms (6)
National Cancer Institute (NCI) (19) · Mayo Clinic (10) · Children's Oncology Group (8) · Columbia University (6) · Duke University (6) · HaEmek Medical Center, Israel (6) · M.D. Anderson Cancer Center (6) · Abant Izzet Baysal University (5) · Alliance for Clinical Trials in Oncology (5) · Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (5) · Centre Hospitalier de Cayenne (5) · NRG Oncology (5) · Roswell Park Cancer Institute (5) · University of Pennsylvania (5) · City of Hope Medical Center (4)
United States (209) · Canada (55) · United Kingdom (39) · France (37) · China (33) · Italy (27) · Spain (20) · Turkey (Türkiye) (19) · Netherlands (16) · Germany (15) · Australia (14) · Puerto Rico (14) · Denmark (12) · Belgium (10) · Israel (9)
Olivier Beauchet, MD (3) · Andrea B. Goldschmidt, Ph.D. (2) · Ariel Koren, MD (2) · Carina Levin, MD (2) · Jacqueline Montes, PT, EdD (2) · Kishore Mulpuri, FRCSC (2) · Leticia Castillo, M.D. (2) · Marcelo A Holanda, PHD (2) · Matthew Crotty, PharmD (2) · Nancy Ip, PhD (2) · Simon Fifer, PhD (2)
PMID 35554583, PMID 10914623, PMID 11112239, PMID 11459755, PMID 11775787, PMID 11832252, PMID 11843075, PMID 12127181, PMID 14586353, PMID 14599700, PMID 15021773, PMID 15449976, PMID 15454805, PMID 16055573, PMID 16307931, PMID 16418463, PMID 16522419, PMID 16908781, PMID 16921051, PMID 17084135, PMID 17110646, PMID 17161082, PMID 17239183, PMID 17289240, PMID 17621365, PMID 17650692, PMID 17786808, PMID 17825674, PMID 17897924, PMID 1798888, PMID 18053373, PMID 18058946, PMID 18408401, PMID 18408402, PMID 18626005, PMID 19026961, PMID 19038077, PMID 19129538, PMID 19249635, PMID 19457604, PMID 19893191, PMID 19918928, PMID 20132984, PMID 20360052, PMID 20430946, PMID 20448073, PMID 20522709, PMID 20823433, PMID 20876603, PMID 21098350
U10CA180820 (10), U10CA180886 (7), U10CA180821 (6), U10CA180868 (6), U10CA021115 (4), U10CA031946 (4), U10CA098543 (4), U10CA180888 (4), P30CA033572 (3), U10CA027469 (3), U10CA180830 (3), 2019 (2), P30CA014599 (2), P30CA016056 (2), P30CA138292 (2)