40 completed, 9 terminated, 4 recruiting, 4 withdrawn. 19 Not applicable, 12 Phase 4, 8 Phase 3, 3 Phase 2.
Follow LivaNova: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment Resistant Depression and Vagus Nerve Stimulation Vagus Nerve Stimulation (VNS), Best Medical Treatment - Treatment Resistant Depression (TRD) | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 166 | 2024-02-19 | 2026-06-23 |
| Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation Hypoglossal Nerve Stimulation - Obstructive Sleep Apnea, OSA | Not applicable | Completed | LivaNova | 107 | 2022-02-24 | 2026-07-17 |
| IMPACT of AspireSR® for VNS Therapy on Healthcare Resource Utilisation and Clinical Outcomes. Epilepsy | Terminated | LivaNova | 15 | 2022-01-20 | 2024-12-03 | |
| Non-interventional Study Describing Healthcare Resource Utilisation and Clinical Outcomes Associated With VNS Therapy in UK. Epilepsy | Terminated | LivaNova | 97 | 2021-05-11 | 2026-03-25 | |
| VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems Vagal nerve stimulation (VNS) - Autoimmune Diseases, Epilepsy | Not applicable | Recruiting | University of Louisville | 30 | 2021-04-01 | 2024-11-25 |
| The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes Treatment Resistant Depression | Terminated | LivaNova | 138 | 2021-03-23 | 2024-12-20 | |
| XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU) Accelerometer Live-Streaming Tool - Epilepsy, Tonic-Clonic | Withdrawn | LivaNova | 2020-03-16 | 2020-08-25 | ||
| A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression Vagus Nerve Stimulation (VNS) - Treatment Resistant Depression | Not applicable | Recruiting | LivaNova | 6800 | 2019-09-26 | 2026-10-21 |
| ANTHEM-HFrEF Pivotal Study VITARIA System - Heart Failure, Heart Failure, Congestive | Not applicable | Terminated | LivaNova | 533 | 2018-05-01 | 2023-10-10 |
| Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study Microburst Stimulation - Epilepsies, Partial, Epilepsy, Tonic-Clonic | Not applicable | Completed | LivaNova | 33 | 2018-02-27 | 2022-10-25 |
| Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. Vagus Nerve Stimulation (VNS) Therapy - Epilepsy, Seizures | Completed | LivaNova | 827 | 2018-02-05 | 2024-11-22 | |
| A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression. Vagal Nerve Simulation (VNS) Therapy - Treatment Resistant Depression | Recruiting | LivaNova | 500 | 2017-12-14 | 2026-08-27 | |
| Behavior of Valve Leaflets Following Aortic Valve Implant 4D Cardiac CT Scan, LivaNova Bioprothetic Aortic Valve Implant - Aortic-valve Replacement | Not applicable | Completed | Corcym S.r.l | 88 | 2017-12-06 | 2024-03-06 |
| Clinical Evaluation of LEft VEntricular Auto Threshold Algorithm (LEVEA) "In-Clinic LVAT" - Heart Failure | Not applicable | Completed | LivaNova | 60 | 2017-02-16 | 2019-05-28 |
| Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction pacemaker diagnostic algorithm, Attended cardiorespiratory sleep study - Sleep Apnea, Arrhythmias, Cardiac | Not applicable | Completed | University Hospital, Caen | 66 | 2016-06-22 | 2026-04-02 |
| PErsonalized and Adaptive Kinesthetic stImulation Therapy, Based on Cardio-respiratory Holter moNitoring, for Sleep Apnea syndrOmes Kinesthetic stimulation - Obstructive Sleep Apnea Syndrome | Not applicable | Completed | LivaNova | 42 | 2016-06-01 | 2017-10-05 |
| The remedē® System for the Treatment of Central Sleep Apnea in Daily Practice Sleep Apnea, Central Sleep Disordered Breathing | Terminated | LivaNova | 31 | 2016-02-01 | 2017-04-06 | |
| Pilot Study to Evaluate the Somnotouch Device to Quantify Spontaneous Baroreflex Sensitivity SOMNOtouch device (Somnomedics), Orthostatic test, Finapres Nova device (FMS system) - Healthy, Heart Failure | Not applicable | Completed | University Hospital, Angers | 46 | 2015-12-01 | 2020-01-07 |
| STIMTAVI : Evolution of Atrioventricular Conduction Disorders After TAVI Pacemaker Implantation, TAVI | Unknown | Association de Recherche en Cardiologie des Alpes | 275 | 2015-11-01 | 2017-11-09 | |
| Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm pacemaker implantation, holter implantation - Post-TAVI | Phase 4 | Unknown | University Hospital, Clermont-Ferrand | 200 | 2015-06-01 | 2016-07-26 |
Showing 20 of 60. Sign in to see all of them.
Heart Failure (15) · Depressive Disorder, Treatment-Resistant (4) · Epilepsy (4) · Sleep Apnea Syndromes (4) · Sleep Apnea, Obstructive (4) · Drug Resistant Epilepsy (3) · Sick Sinus Syndrome (3) · Arrhythmias, Cardiac (2) · Atrioventricular Block (2) · Bradycardia (2) · Cardiovascular Diseases (2) · Death, Sudden, Cardiac (2) · Depression (2) · Epilepsy, Tonic-Clonic (2) · Heart Valve Diseases (2)
Vagus Nerve Stimulation (4) · Ramipril (2) · Therapeutics (2) · Captopril (1) · Lisinopril (1) · trandolapril (1)
France (30) · United States (21) · Germany (16) · Italy (15) · Belgium (14) · Spain (12) · United Kingdom (11) · Portugal (8) · Canada (7) · Netherlands (4) · Austria (3) · Denmark (2) · Israel (2) · Japan (2) · Switzerland (2)
Charles Conway, MD (2) · Dan Dan, MD (2) · Alan R Schwartz, MD (1) · Albert Hagege, MD, PhD (1) · Alexander Bauer (1) · Allan Young, Prof. (1) · Angelo Auricchio, MD, PHD (1) · Anselm Gitt, MD (1) · Antonio Campanella, MD (1) · Atul Malhotra, MD (1) · Barbara Wysota (1) · Carsten W Israel (1)
PMID 15376771, PMID 15559738, PMID 15769702, PMID 16283980, PMID 19723694, PMID 20031837, PMID 20437790, PMID 21771823, PMID 22098690, PMID 22179034, PMID 22394464, PMID 22921821, PMID 25092878, PMID 25282033, PMID 27797979, PMID 31722536, PMID 32993573, PMID 33625762, PMID 35018342, PMID 35613672, PMID 37022679, PMID 37384278, PMID 38194603, PMID 38340111, PMID 38499287, PMID 38532258, PMID 38574853, PMID 39180426, PMID 39701918, PMID 39706521, PMID 39722333, PMID 40021060, PMID 40673907, PMID 41529263, PMID 41690459, PMID 42008810, PMID 42159539, PMID 42447264