223 completed, 83 unknown, 69 recruiting, 40 terminated. 134 Not applicable, 46 Phase 2, 42 Phase 3, 33 Phase 4, 20 Phase 1.
Follow Ventricular Dysfunction: new trials by email Literature Review of Ventricular Dysfunction trials Research Report on Ventricular Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia Ferrous sulfate 325mg - Right Ventricular Dysfunction, Hypoxia | Early Phase 1 | Not yet recruiting | University of Colorado, Denver | 5 | 2028-03-01 | 2026-04-29 |
| Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis, Tissue Plasminogen Activator - Pulmonary Embolism, Right Ventricular Dysfunction | Suspended | Brigham and Women's Hospital | 60 | 2027-01-01 | 2026-01-21 | |
| Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0) Right Ventricular Dysfunction, Cardiopulmonary Diseases | Not yet recruiting | IRCCS SYNLAB SDN | 2000 | 2027-01-01 | 2026-10-01 | |
| Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer | Not applicable | Not yet recruiting | University of Minnesota | 72 | 2026-10-29 | 2026-10-06 |
| Sacubitril/Valsartan Versus Valsartan Alone on Left Atrial Volume Index in Hypertensive Patients Sacubitril / Valsartan, Valsartan - Hypertension, Left Ventricular Diastolic Dysfunction | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 102 | 2026-10-01 | 2026-10-02 |
| Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP) - Bradycardia, Atrioventricular Block | Not applicable | Not yet recruiting | Yonsei University | 300 | 2026-10-01 | 2026-09-04 |
| Pulmonary Hypertension and RV Dysfunction in Myeloproliferative Neoplasms Myeloproliferative Neoplasm, Right Ventricular Dysfunction | Not yet recruiting | Assiut University | 145 | 2026-09-20 | 2026-09-22 | |
| Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research Pericarditis, Tako-TSUBO Cardiomyopathy | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 300 | 2026-09-01 | 2026-08-10 | |
| Federated Learning for Point-of-Care Cardiac Ultrasound Focused Cardiac Point-of-Care Ultrasonography, FL-POCUS Federated Machine-Learning Analysis System - Ventricular Dysfunction, Left, Ventricular Function, Left | Enrolling by invitation | Truway Health, Inc. | 3000 | 2026-08-31 | 2026-09-02 | |
| AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECG SmartECG-EF - Heart Failure, Atrial Fibrillation (AF) | Not yet recruiting | Inha University Hospital | 300 | 2026-08-30 | 2026-09-28 | |
| Menopausal Hormone Therapy And Left Ventricular Function Menopausal Hormone Therapy - Menopause, Left Ventricular Dysfunction | Recruiting | Mayo Clinic | 50 | 2026-08-26 | 2026-08-27 | |
| Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. Temporary left bundle branch area pacing, Temporary leadless right ventricular pacing - Pacemaker-Induced Cardiomyopathy, Tricuspid Regurgitation | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 20 | 2026-08-18 | 2026-08-21 | |
| STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure Stepwise Withdrawal of ARNI and SGLT2i, Continued Guideline-Directed Medical Therapy - Heart Failure With Reduced Ejection Fraction, Heart Failure | Phase 4 | Recruiting | Kyungsub Song | 80 | 2026-08-12 | 2026-09-02 |
| Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension Midodrine Oral Tablet - Heart Failure With Reduced Ejection Fraction, Hypotension | Phase 2 / Phase 3 | Recruiting | Ottawa Heart Institute Research Corporation | 56 | 2026-08-07 | 2026-09-08 |
| PASCAL Precision-GDMT Registry Tricuspid Insufficiency, Tricuspid Regurgitation (TR) | Not yet recruiting | Ceric Sàrl | 50 | 2026-08-01 | 2026-05-13 | |
| Micro-axial Flow Pump-Supported PCI in Complex Coronary Artery Disease With Ischemic LV Dysfunction Microaxial pump-supported PCI, Optimal medical therapy (OMT) - Coronary Artery Disease (CAD) | Not applicable | Not yet recruiting | China National Center for Cardiovascular Diseases | 452 | 2026-08-01 | 2026-07-01 |
| Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE) Kosmos Torso-One AI-guided Point-of-Care Ultrasound (EchoNous, Inc.) - Valvular Heart Disease Patients, Aortic Stenosis | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 1088 | 2026-08-01 | 2026-08-17 |
| Sotagliflozin as Prevention of Anthracycline-Related Cardiotoxicity Sotagliflozin, Placebo - Anthracycline-induced Cardiotoxicity, Lymphoma | Phase 2 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 60 | 2026-07-01 | 2026-05-07 |
| The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial Echocardiography - Critical Illness, Elevated Left Atrial Pressure | Recruiting | Queen Mary Hospital, Hong Kong | 50 | 2026-07-01 | 2026-09-15 | |
| Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance Routine clinical care (no study intervention) - Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension | Recruiting | Azienda Ospedaliero-Universitaria Careggi | 5000 | 2026-06-19 | 2026-10-15 |
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Ventricular Dysfunction, Left (254) · Heart Failure (148) · Ventricular Dysfunction, Right (88) · Takotsubo Cardiomyopathy (63) · Myocardial Infarction (33) · Heart Diseases (31) · Cardiovascular Diseases (30) · Cardiomyopathies (27) · Coronary Artery Disease (19) · Hypertension, Pulmonary (18) · Arrhythmias, Cardiac (15) · Pulmonary Embolism (15) · Death, Sudden, Cardiac (13) · Heart Failure, Systolic (13)
Cardiovascular Diseases (441) · Heart Diseases (440) · Pathological Conditions, Signs and Symptoms (163) · Pathologic Processes (140) · Vascular Diseases (131) · Cardiomyopathies (66) · Myocardial Ischemia (66) · Respiratory Tract Diseases (60) · Ventricular Dysfunction, Left (60) · Lung Diseases (51) · Ischemia (45) · Necrosis (44) · Infarction (43) · Arrhythmias, Cardiac (29)
Echocardiography (24) · Cardiac Resynchronization Therapy (7) · Valsartan (7) · Carvedilol (6) · Simendan (5) · dapagliflozin (5) · sacubitril and valsartan sodium hydrate drug combination (5) · Magnetic Resonance Spectroscopy (4) · Tissue Plasminogen Activator (4) · apixaban (4) · Control Groups (3) · Defibrillators, Implantable (3) · Dobutamine (3) · Electrocardiography (3) · Metoprolol (3)
Abbott Medical Devices (15) · Assistance Publique - Hôpitaux de Paris (9) · Assiut University (9) · Medtronic Cardiac Rhythm and Heart Failure (8) · Mayo Clinic (7) · University of Aberdeen (6) · Bayer (5) · Montreal Heart Institute (5) · University of Colorado, Denver (5) · University of Sao Paulo (5) · Yonsei University (5) · Cedars-Sinai Medical Center (4) · Eko Devices, Inc. (4) · National Defense Medical Center, Taiwan (4) · Post Graduate Institute of Medical Education and Research, Chandigarh (4)
United States (132) · Germany (52) · Italy (47) · United Kingdom (47) · France (40) · Canada (37) · Netherlands (26) · China (22) · Czechia (22) · Denmark (19) · Spain (18) · Sweden (18) · Switzerland (18) · Poland (17) · Austria (15)
Robert Simari, MD (4) · Abhiram Prasad, MD (2) · Carlo Gazzola, B. Sc. (2) · Cheng-Wei Liu, M.D. (2) · Dana Dawson, MD, MRCP (2) · Derliz Mereles, M.D. (2) · Eduardo Marban, MD, PhD (2) · Jonatan Oras, MD, PhD (2) · Joseph B Selvanayagam, MBBS (2) · Mattia Cattaneo, MD (2) · Partho Sengupta, MD (2) · Patrick O'Gara, MD (2) · Peter Goettel, MD (2)
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U01HL087318 (3), 2016 (2), 2023 (2), U01HL088942 (2), U54HL081028 (2), 2005 (1), 2008 (1), 2009 (1), 2014 (1), 2015 (1), 2019 (1), 5UM1HL087318 (1), K23HL148394 (1), P01HL076611 (1), P50HL074734 (1)