15 completed, 10 unknown, 8 recruiting, 5 not yet recruiting. 9 Phase 3, 7 Not applicable, 6 Phase 4, 5 Phase 2, 2 Early Phase 1.
Follow Vasoplegia: new trials by email Literature Review of Vasoplegia trials Research Report on Vasoplegia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Hemoadsorption on Vascular Integrity in Septic Shock CytoSorb hemoadsorption, Standard Medical Therapy (SMT) - Septic Shock | Not applicable | Not yet recruiting | Semmelweis University | 110 | 2026-09-01 | 2026-07-17 |
| Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock Dexmedetomidine 100 µg/mL, intravenous solution, Stardard care - Septic Shock, Vasopressor Resistance | Phase 3 | Not yet recruiting | Hospices Civils de Lyon | 360 | 2026-09-01 | 2026-05-06 |
| Angiotensin II for Post Cardiac Surgery Vasoplegia (ANGII_V) Angiotensin II (Giapreza®) - Vasoplegic Shock, Cardiopulmonary Bypass | Phase 4 | Not yet recruiting | Methodist Healthcare System of San Antonio | 329 | 2026-07-01 | 2026-06-26 |
| GENECARD - the Use of Genetic, Epigenetic, Metabolomic, Proteomic and Microbiotic Markers, Image and Voice Biomarker Analyses, and Pre- and Intraoperative Clinical Data - to Predict Early Complications After Cardiac Surgery. Multi-Omics Data and Clinical Data Collection - Postoperative Delirium (POD), Postoperative Bleeding | Not yet recruiting | Medical University of Gdansk | 3000 | 2026-01-01 | 2026-01-15 | |
| Effect Inhaled Nitric Oxide in Adult Liver Transplant Prospective iNO Administration ("After" Group), No Intervention Retrospective "Before" Group - Liver Diseases, Reperfusion Injury | Not applicable | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 260 | 2025-09-01 | 2025-08-15 |
| Femoral Versus Radial Invasive Arterial Pressure Monitoring in Cardiac Surgery Patients Femoral artery catheterization for continuous invasive arterial blood pressure monitoring, Radial artery catheterization for continuous invasive arterial blood pressure monitoring - Vasoplegia Syndrome, Vasoplegia | Not applicable | Recruiting | Guillaume BESCH | 340 | 2025-06-15 | 2025-12-22 |
| Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II Angiotensin II, Noradrenalin - Cardiac Surgery, Vasoplegia | Phase 3 | Recruiting | Universität Münster | 1022 | 2025-03-31 | 2025-07-18 |
| Evaluation of the HPA Axis in Patients With Vasoplegic Syndrome After Cardiac Surgery Blood sampling, Vital status - Vasoplegic Syndrome in Adult Cardiac Surgery | Recruiting | Assistance Publique - Hôpitaux de Paris | 200 | 2025-03-05 | 2026-01-30 | |
| Angiotensin II Stress Test. Renin Kinetics During Treatment of Vasoplegic Shock With Angiotensin II. Shock, Vasoplegic Syndrome | Recruiting | University Medical Centre Maribor | 121 | 2024-08-01 | 2026-09-16 | |
| Characterisation of Endothelial Cells in Different Inflammatory Pathologies Endothelial cell biopsy - Sepsis, Vasoplegia | Recruiting | Royal Surrey County Hospital NHS Foundation Trust | 105 | 2024-07-16 | 2024-09-25 | |
| Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery Vit C, Standard Preparation - Vasoplegia Syndrome | Not applicable | Completed | Southeast University, China | 40 | 2024-07-01 | 2026-09-16 |
| In Situ Exploration of Vascular Function in Vasoplegic Shock Following Cardiac Surgery With Cardiopulmonary Bypass Cardiac Surgical Procedures | Unknown | University Hospital, Rouen | 124 | 2024-02-05 | 2024-03-19 | |
| Occult Vasoplegia in Normotensive Sepsis: Early Prediction With Diastolic Index and Lactate Sepsis, Vasoplegia | Completed | Hospital H+ Queretaro | 526 | 2024-01-01 | 2026-06-18 | |
| Endotoxinemia and Vasoplegia Following Cardiothoracic Surgery With Cardiopulmonary Bypass (CPB) Patients with cardiopulmonary bypass - Vasoplegia, Vasoplegic Shock | Unknown | Universität Münster | 200 | 2023-10-02 | 2023-12-11 | |
| Norepinephrine Weaning Guided by the Hypotension Prediction Index in Vasoplegic Shock After Cardiac Surgery norepinephrine weaning protocol, norepinephrine weaning protocol and guided by the HPI - Vasoplegia, Shock | Not applicable | Unknown | Centre Hospitalier Universitaire, Amiens | 142 | 2023-09-01 | 2024-07-03 |
| Differential Regulation of RAAS-axis in Patients Undergoing Cardiac Surgery on-pump surgery, off-pump surgery - Vasoplegia, Vasoplegic Shock | Recruiting | Universität Münster | 40 | 2023-08-24 | 2024-12-12 | |
| POLECAT: Perioperative Delta Renin Concentration Post Operative Vasoplegic Syndrome, Acute Kidney Injury | Unknown | Royal Surrey County Hospital NHS Foundation Trust | 405 | 2023-07-01 | 2023-07-12 | |
| Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation Vasopressin, Norepinephrine, Collection of clinical data - Scheduled Cardiac Surgery With Extracorporeal Circulation, Vasoplegic Syndrome | Phase 3 | Active not recruiting | Centre Hospitalier Universitaire Dijon | 840 | 2023-01-02 | 2025-12-22 |
| Reperfusion Syndrome and Vasoplegic Syndrome in Liver Transplant Surgery noradrenaline/adrenaline - Postperfusion Syndrome | Completed | Hospital Universitari Vall d'Hebron Research Institute | 246 | 2022-12-13 | 2023-02-21 | |
| Angiotensin II in Liver Transplantation Angiotensin II, Saline - Liver Transplant; Complications, Vasoplegia | Phase 2 / Phase 3 | Active not recruiting | University of California, San Francisco | 50 | 2022-06-28 | 2026-03-20 |
Showing 20 of 45. Sign in to see all of them.
Shock, Septic (7) · Acute Kidney Injury (6) · Sepsis (6) · Shock (5) · Hypotension (4) · Fibrosis (2) · Shock, Cardiogenic (2) · Acute-On-Chronic Liver Failure (1) · Atrial Fibrillation (1) · Burns (1) · Cardiovascular Diseases (1) · Communicable Diseases (1) · Coronary Artery Disease (1) · Critical Illness (1)
Pathologic Processes (45) · Pathological Conditions, Signs and Symptoms (45) · Vascular Diseases (45) · Cardiovascular Diseases (44) · Postoperative Complications (44) · Inflammation (9) · Infections (8) · Systemic Inflammatory Response Syndrome (8) · Shock (7) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Kidney Diseases (6) · Male Urogenital Diseases (6) · Renal Insufficiency (6) · Urogenital Diseases (6)
Angiotensin II (5) · Hydroxocobalamin (4) · Norepinephrine (4) · Ascorbic Acid (3) · Giapreza (3) · Methylene Blue (3) · Saline Solution (3) · Hydrocortisone (2) · Midodrine (2) · Sodium Chloride (2) · Vitamin B 12 (2) · Blood Specimen Collection (1) · Bupivacaine (1) · Cardiopulmonary Bypass (1) · Dexmedetomidine (1)
Centre Hospitalier Universitaire, Amiens (6) · Universität Münster (4) · Mayo Clinic (3) · Royal Surrey County Hospital NHS Foundation Trust (2) · Ain Shams University (1) · Assistance Publique - Hôpitaux de Paris (1) · Austin Health (1) · Australian and New Zealand Intensive Care Research Centre (1) · Beijing Anzhen Hospital (1) · Bürgerspital Solothurn (1) · Centre Hospitalier Universitaire Dijon (1) · CytoSorbents, Inc (1) · Dartmouth-Hitchcock Medical Center (1) · Guillaume BESCH (1) · Hospices Civils de Lyon (1)
France (13) · United States (6) · Germany (5) · Brazil (3) · Australia (2) · China (2) · Poland (2) · Spain (2) · Austria (1) · Canada (1) · Egypt (1) · Hungary (1) · India (1) · Italy (1) · Mexico (1)
Alexander Zarbock, MD (4) · Bianca Meneguini (1) · Choy Lewis, MD (1) · Dina Badre, MD (1) · Duska Dragun, MD (1) · Edecio Cunha-Neto (1) · Erica D Wittwer (1) · Guillaume Besch, M.D., Ph.D. (1) · James A. Nelson, M.B.B.S. (1) · Jingyuan Xu, M.D. (1)
PMID 11588440, PMID 12500513, PMID 15821641, PMID 16134766, PMID 16731105, PMID 19406978, PMID 19948019, PMID 20109575, PMID 23845791, PMID 24151551, PMID 24940436, PMID 25286986, PMID 26492477, PMID 26953217, PMID 28120005, PMID 28327122, PMID 28528561, PMID 29077618, PMID 29223724, PMID 29509568, PMID 30407370, PMID 30653055, PMID 31107279, PMID 31142242, PMID 31334462, PMID 31723628, PMID 31950979, PMID 32028998, PMID 32145658, PMID 32520577, PMID 32609011, PMID 32882250, PMID 32882263, PMID 3303534, PMID 33231111, PMID 33320784, PMID 33564993, PMID 33648544, PMID 33976254, PMID 34017263, PMID 34166293, PMID 34391450, PMID 35171852, PMID 35246227, PMID 35915923, PMID 36012398, PMID 36117167, PMID 36123067, PMID 36524274, PMID 36930693
2014 (1), 2015 (1), 2025 (1)