Renal Insufficiency: Clinical Trials

4139 completed, 1096 unknown, 709 recruiting, 477 terminated. 2308 Not applicable, 862 Phase 2, 758 Phase 1, 727 Phase 4, 700 Phase 3.

By phase and status

Phase	Trials	Status
Not applicable	2308	Completed 1243, Unknown 351, Recruiting 251, Not yet recruiting 159, Terminated 145, Active not recruiting 79, Withdrawn 56, Enrolling by invitation 20, Suspended 4
Phase 2	862	Completed 491, Terminated 98, Unknown 90, Recruiting 81, Withdrawn 42, Not yet recruiting 28, Active not recruiting 21, Enrolling by invitation 6, Suspended 5
Phase 1	758	Completed 552, Recruiting 52, Terminated 51, Unknown 45, Not yet recruiting 23, Withdrawn 17, Active not recruiting 16, Enrolling by invitation 1, Suspended 1
Phase 4	727	Completed 388, Unknown 129, Terminated 69, Recruiting 53, Withdrawn 37, Not yet recruiting 23, Active not recruiting 20, Enrolling by invitation 4, Suspended 4
Phase 3	700	Completed 431, Terminated 82, Unknown 74, Recruiting 47, Active not recruiting 24, Withdrawn 23, Not yet recruiting 14, Suspended 3, Enrolling by invitation 2
Early Phase 1	46	Completed 24, Recruiting 7, Not yet recruiting 4, Active not recruiting 3, Enrolling by invitation 2, Terminated 2, Unknown 2, Withdrawn 2

Follow Renal Insufficiency: new trials by email Literature Review of Renal Insufficiency trials Research Report on Renal Insufficiency

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Maastricht Investigation of Renal Function in Absence of- and Post- Contrast in Patients With eGFR LEss Than 30 serum creatinine assay - Acute Kidney Injury (Nontraumatic), Contrast-induced Nephropathy		Withdrawn	Maastricht University Medical Center		2097-11-01	2023-10-19
Time to Excretion of Contrast, a Maastricht Prospective Observational Study Contrast concentration in urine - Renal Insufficiency, Acute Kidney Injury		Withdrawn	Maastricht University Medical Center		2097-11-01	2023-10-19
Efficacy of Point-Of-Care Creatinine Assays in Patients With eGFR <30 Receiving Intravascular Contrast serum creatinine assay - Renal Insufficiency, Acute Kidney Injury		Withdrawn	Maastricht University Medical Center		2097-05-01	2023-10-19
MRI Technical Development and Applications in Kidney Disease Chronic Kidney Diseases, Kidney Transplantation		Not yet recruiting	University of Minnesota	180	2028-06-30	2026-04-13
Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury PRECISE-AKI Clinical Decision Support Tool - Acute Kidney Injury (AKI)	Not applicable	Not yet recruiting	VA Office of Research and Development	60	2028-01-01	2026-11-02
Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	100	2027-10-01	2026-09-03
Amino Acid Therapy Evaluating the Incidence of New-Onset AKI Amino Acid infusion, Lactated Ringer Solution - Acute Kidney Injury	Phase 2	Not yet recruiting	Children's Hospital Medical Center, Cincinnati	270	2027-10-01	2026-10-21
Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided) - End-Stage Renal Disease, Chronic Kidney Diseases	Not applicable	Not yet recruiting	State University of New York at Buffalo	550	2027-10-01	2026-10-20
DESIR. Evaluation of the Pre-therapeutic Activity of Dihydropyrimidine dEShydrogenase (DPD) in Patients With Cancer and/or Renal Failure blood sampling, Blood sampling - Renal Impairment, Digestive Cancers		Not yet recruiting	Centre Hospitalier Universitaire de Besancon	742	2027-10-01	2026-11-02
Anti-Interleukin-6 (IL6) in Calciphylaxis Tocilizumab - Calciphylaxis	Phase 1	Not yet recruiting	Boston Medical Center	10	2027-09-01	2026-07-16
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health INTEGRATE-CHW, Usual Care - Hypertension (HTN), CKD - Chronic Kidney Disease	Not applicable	Not yet recruiting	Florida International University	200	2027-07-15	2026-11-05
Sarcopenia in Chronic Kidney Disease (CKD) Patients Valine, EEA - Chronic Kidney Disease, Sarcopenia	Early Phase 1	Not yet recruiting	The University of Texas Health Science Center at San Antonio	20	2027-07-01	2026-11-02
Kidney RISE: Randomized Integrated Supportive CarE Trial Kidney RISE - Chronic Kidney Disease (Stages 4 and 5)	Not applicable	Not yet recruiting	NYU Langone Health	280	2027-05-01	2026-08-03
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b Combined Training, Multicomponent Training - Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B	Not applicable	Not yet recruiting	University of Brasilia	57	2027-05-01	2026-10-30
Breakthrough - T1DM and Chronic Kidney Disease Tegoprubart, Islet Cell Transplant - Diabete Type 1, Chronic Kidney Disease	Phase 1 / Phase 2	Recruiting	University of Chicago	10	2027-04-29	2026-08-20
Insights Into the Continuous Renal Replacement Therapy to Critical Ill Patients continuous renal replacement therapy - Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury		Not yet recruiting	University of Alberta	100000	2027-03-31	2026-09-09
PATH-03 Paraguay Feasibility Study ePATH System will be used to create an endoAVF - Kidney Disease, End-Stage	Not applicable	Not yet recruiting	Pathfinder Medical	20	2027-03-01	2026-09-17
Days-Off Versus Daily Initial Peritoneal Dialysis Prescription Daily Peritoneal Dialysis, Days-off Peritoneal Dialysis - Kidney Failure	Not applicable	Not yet recruiting	University of Michigan	450	2027-02-01	2026-11-06
Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis Bupropion Hydrochloride 150 MG - End Stage Renal Disease, Fatigue	Phase 1 / Phase 2	Not yet recruiting	The University of Texas Health Science Center at San Antonio	16	2027-02-01	2026-11-02
Effects of Replacing High Protein Foods in People With Chronic Kidney Disease Controlled dietary intervention - Chronic Kidney Disease Stage 3	Not applicable	Recruiting	Indiana University	15	2027-02-01	2026-11-09

Showing 20 of 7358. Sign in to see all of them.

Narrower conditions

Renal Insufficiency, Chronic (3095)  ·  Kidney Failure, Chronic (2009)  ·  Acute Kidney Injury (1622)  ·  Kidney Diseases (340)  ·  Hypertension (262)  ·  Diabetes Mellitus (261)  ·  Heart Failure (256)  ·  Anemia (251)  ·  Diabetes Mellitus, Type 2 (245)  ·  Cardiovascular Diseases (204)  ·  Inflammation (128)  ·  Sepsis (121)  ·  Critical Illness (106)  ·  Motor Activity (102)

Broader conditions

Female Urogenital Diseases (7357)  ·  Female Urogenital Diseases and Pregnancy Complications (7357)  ·  Male Urogenital Diseases (7357)  ·  Urogenital Diseases (7352)  ·  Urologic Diseases (7332)  ·  Kidney Diseases (7018)  ·  Pathological Conditions, Signs and Symptoms (5388)  ·  Pathologic Processes (5283)  ·  Disease Attributes (4922)  ·  Chronic Disease (4773)  ·  Renal Insufficiency, Chronic (1683)  ·  Cardiovascular Diseases (1064)  ·  Nutritional and Metabolic Diseases (1043)  ·  Metabolic Diseases (926)

Interventions

Blood Specimen Collection (72)  ·  Exercise (72)  ·  Saline Solution (71)  ·  dapagliflozin (67)  ·  Tacrolimus (64)  ·  Sodium Chloride (63)  ·  Standard of Care (60)  ·  Darbepoetin alfa (54)  ·  Epoetin Alfa (50)  ·  Sevelamer (49)  ·  paricalcitol (49)  ·  Mycophenolic Acid (48)  ·  Sodium Bicarbonate (47)  ·  empagliflozin (42)  ·  finerenone (40)

Sponsors

Assiut University (86)  ·  AstraZeneca (76)  ·  Amgen (73)  ·  Bayer (65)  ·  National Taiwan University Hospital (57)  ·  Novartis Pharmaceuticals (51)  ·  Hospices Civils de Lyon (48)  ·  Vantive Health LLC (45)  ·  Seoul National University Hospital (43)  ·  Assistance Publique - Hôpitaux de Paris (42)  ·  Massachusetts General Hospital (41)  ·  London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (38)  ·  Brigham and Women's Hospital (37)  ·  Pfizer (35)  ·  University of California, San Francisco (35)

Countries

United States (2333)  ·  France (570)  ·  China (535)  ·  Germany (509)  ·  Canada (439)  ·  United Kingdom (410)  ·  Italy (335)  ·  Spain (318)  ·  South Korea (258)  ·  Turkey (Türkiye) (242)  ·  Taiwan (226)  ·  Brazil (224)  ·  Belgium (218)  ·  Poland (205)  ·  Denmark (186)

Top investigators

Alp Ikizler, MD (19)

Results publications

PMID 40576086, PMID 36005278, PMID 36791280, PMID 35018639, PMID 36416787, PMID 35224730, PMID 37916745, PMID 34519356, PMID 33314078, PMID 33586138, PMID 37870148, PMID 38189593, PMID 32390133, PMID 38770818, PMID 39878152, PMID 36472416, PMID 33283264, PMID 34164803, PMID 37651553, PMID 39607014, PMID 32588430, PMID 33782940, PMID 38018702, PMID 39963952, PMID 33107592, PMID 39356039, PMID 23797006, PMID 32446407, PMID 39301879, PMID 39498822, PMID 41196655, PMID 19558344, PMID 23343061, PMID 23343062, PMID 32734207, PMID 36039153, PMID 36472884, PMID 38299639, PMID 38899545, PMID 40333016, PMID 40359056, PMID 41198855, PMID 41805697, PMID 15312219, PMID 18328118, PMID 18926433, PMID 20721651, PMID 20925544, PMID 21336114, PMID 21545947

NIH funding

2023 (39), 2016 (25), 2017 (20), 2018 (19), 2025 (19), 2014 (18), 2008 (17), 2015 (17), 2019 (17), 2009 (16), 2005 (6), 2004 (5), R01DK045604 (3), R01DK071696 (3), R01DK113191 (3)