55 completed, 31 unknown, 26 recruiting, 5 active not recruiting. 43 Not applicable, 9 Phase 4, 3 Phase 2, 2 Phase 3, 1 Early Phase 1.
Follow Valvular Heart Disease: new trials by email Literature Review of Valvular Heart Disease trials Research Report on Valvular Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Echocardiographic Assessment of Valvular Dysfunction in Children With CHD Congenital Heart Disease, Valvular Heart Disease | Not yet recruiting | Assiut University | 100 | 2026-10-10 | 2026-10-08 | |
| Spanish Prospective Registry of Hydra THV for Transcatheter Aortic Valve Implantation Hydra THV - Severe Aortic Valve Stenosis, Valvular Heart Disease | Recruiting | Fundación EPIC | 100 | 2026-07-07 | 2026-10-30 | |
| Cardiovascular Acoustics for Early Disease Detection Valvular Heart Disease, Coronary Artery Disease | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 500 | 2026-06-10 | 2026-10-28 | |
| Longitudinal Validation of CIRC Technologies Cardiovascular Diseases, Heart Failure | Recruiting | The Cleveland Clinic | 1000 | 2026-05-06 | 2026-07-31 | |
| Diagnostic Study of Structural Heart Disease Based on Cardiac Electromechanical Signals Transthoracic Echocardiography - Valvular Heart Disease | Not yet recruiting | First Affiliated Hospital Xi'an Jiaotong University | 1300 | 2026-05-01 | 2026-05-22 | |
| A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease Echocardiogram - Pulmonary Vascular Disease, Valvular Heart Disease | Recruiting | Mayo Clinic | 600 | 2026-04-28 | 2026-06-18 | |
| DELINEATE-Prospective Valve Disease, Aortic, Mitral Regurgitation (MR) | Recruiting | Columbia University | 50 | 2026-04-15 | 2026-04-16 | |
| Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery robot-assisted surgery - Coronary Bypass Graft Stenosis, Valvular Heart Disease | Not yet recruiting | Taichung Veterans General Hospital | 80 | 2025-11-01 | 2025-09-09 | |
| MULTIVALVE : A Prospective Multicentre Study of Multiple and Mixed Valvular Heart Disease Valvular Heart Disease | Recruiting | French Cardiology Society | 1000 | 2025-10-30 | 2026-06-12 | |
| Optimized Expansion of the Implanted Transcatheter Aortic Valve OptEx-TAVI, SoC-TAVI - Aortic Stenosis Disease, Valvular Heart Disease | Not applicable | Recruiting | Ole De Backer | 1010 | 2025-10-05 | 2026-07-10 |
| Mechanism and Effect of Novel Metabolites on Valvular Heart Disease Valvular Heart Disease | Recruiting | Sun Yat-sen University | 4000 | 2025-08-01 | 2025-09-02 | |
| Comparing Measurements of the Aortic Valve Taken During Surgery With Those Obtained Before Surgery Using Computed Tomography Scans, in Patients Undergoing Surgical Aortic Valve Replacement The measurements taken from the CT scan will be used to determine the appropriate size for two types of theoretical Transcatheter Aortic Valve Replacement (TAVR) prostheses - Valvular Heart Disease | Not applicable | Recruiting | Maria Cecilia Hospital | 82 | 2025-06-25 | 2026-05-08 |
| Evaluation of Valvular Heart Disease Using Cardiac CT Valvular Heart Disease | Recruiting | Toho University | 350 | 2025-03-12 | 2026-10-09 | |
| Screening of Valvular Heart Disease Using Single-channel Electrocardiogram No intervention (observational study) - Valvular Heart Disease Stenosis and Regurgitation, Valvular Heart Disease | Recruiting | I.M. Sechenov First Moscow State Medical University | 1200 | 2025-01-01 | 2025-08-01 | |
| AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor 15-minutes of sitting during COR ECG Acquistion - Ventricular Ejection Fraction, LVF | Recruiting | Peerbridge Health, Inc | 2000 | 2024-11-21 | 2026-06-01 | |
| a Foundational Model for Cardiovascular Disease Diagnosis and Prediction No Interventions - Coronary Heart Disease (CHD), Heart Failure | Unknown | Shanghai Zhongshan Hospital | 1000000 | 2024-10-01 | 2024-09-19 | |
| Abbott Structural Heart Device Registry Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices - Heart Diseases, ASD - Atrial Septal Defect | Recruiting | Abbott Medical Devices | 2500 | 2024-08-21 | 2026-09-01 | |
| Prehabilitation for Patients Undergoing Elective Cardiac Surgery Physical exercise, Educational program and respiration physiotherapy - Coronary Artery Disease, Valvular Heart Disease | Not applicable | Completed | Hospital Universitario 12 de Octubre | 86 | 2024-06-01 | 2026-07-15 |
| Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4) Hypothermic Cardiopulmonary Bypass, Normothermic Cardiopulmonary Bypass - Ischemic Heart Disease, Valvular Heart Disease | Not applicable | Recruiting | University of Leicester | 100 | 2024-05-20 | 2025-04-03 |
| Detection of Valvular Heart Disease Using Artificial Intelligence-based Stethoscope artificial intelligence-based stethoscope - Valvular Heart Disease | Unknown | Xiao-dong Zhuang | 2000 | 2024-05-01 | 2024-04-26 |
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Heart Valve Diseases (127) · Coronary Artery Disease (27) · Heart Failure (21) · Aortic Valve Stenosis (18) · Myocardial Ischemia (13) · Atrial Fibrillation (12) · Cardiovascular Diseases (12) · Mitral Valve Insufficiency (9) · Heart Diseases (8) · Tricuspid Valve Insufficiency (8) · Aortic Diseases (5) · Arrhythmias, Cardiac (5) · Heart Defects, Congenital (5) · Aortic Valve Insufficiency (3) · Cardiomyopathies (3)
Heart Diseases (119) · Cardiovascular Diseases (115) · Vascular Diseases (46) · Pathological Conditions, Signs and Symptoms (31) · Arterial Occlusive Diseases (28) · Arteriosclerosis (28) · Coronary Disease (26) · Myocardial Ischemia (26) · Pathologic Processes (25) · Aortic Valve Disease (18) · Ventricular Outflow Obstruction (18) · Arrhythmias, Cardiac (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Congenital Abnormalities (8) · Cardiovascular Abnormalities (7)
Blood Specimen Collection (3) · Echocardiography (3) · Propofol (2) · Saline Solution (2) · Sevoflurane (2) · Anesthesia (1) · Bretschneider cardioplegic solution (1) · Cardiac Surgical Procedures (1) · Coronary Artery Bypass (1) · Dexamethasone (1) · Diagnostic Imaging (1) · Echocardiography, Stress (1) · Etomidate (1) · Exercise (1) · HES 130-0.4 (1)
Konkuk University Medical Center (7) · Abbott Medical Devices (4) · Yonsei University (4) · Medical University of Vienna (3) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Assiut University (2) · China National Center for Cardiovascular Diseases (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · I.M. Sechenov First Moscow State Medical University (2) · Insel Gruppe AG, University Hospital Bern (2) · LMU Klinikum (2) · Medtronic Cardiac Rhythm and Heart Failure (2) · Qianfoshan Hospital (2) · Shanghai Zhongshan Hospital (2) · Sheba Medical Center (2)
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PMID 10814642, PMID 14667752, PMID 15221572, PMID 16438759, PMID 17218108, PMID 22797672, PMID 23062541, PMID 23547127, PMID 23950762, PMID 23962460, PMID 25488042, PMID 25760680, PMID 25791027, PMID 25999108, PMID 26432749, PMID 26437535, PMID 26994130, PMID 27465213, PMID 27582763, PMID 28860229, PMID 28943263, PMID 28977361, PMID 29281101, PMID 29318795, PMID 29406579, PMID 29514224, PMID 29746650, PMID 30613413, PMID 30908754, PMID 31020819, PMID 31200756, PMID 31933658, PMID 32015566, PMID 32661631, PMID 32962417, PMID 33045224, PMID 33196155, PMID 33371022, PMID 33399006, PMID 33899504, PMID 35078841, PMID 35111828, PMID 35347997, PMID 35608032, PMID 35753968, PMID 36256693, PMID 36299870, PMID 37070491, PMID 37750105, PMID 38078710
R01AG073633 (1), R01HL133667 (1), R01HL151704 (1)