25 completed, 8 unknown, 5 recruiting, 2 active not recruiting. 43 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 43 | Completed 25, Unknown 8, Recruiting 5, Active not recruiting 2, Enrolling by invitation 1, Terminated 1, Withdrawn 1 |
Follow Valvular Heart Disease: new trials by email Literature Review of Valvular Heart Disease trials Research Report on Valvular Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimized Expansion of the Implanted Transcatheter Aortic Valve OptEx-TAVI, SoC-TAVI - Aortic Stenosis Disease, Valvular Heart Disease | Not applicable | Recruiting | Ole De Backer | 1010 | 2025-10-05 | 2026-07-10 |
| Comparing Measurements of the Aortic Valve Taken During Surgery With Those Obtained Before Surgery Using Computed Tomography Scans, in Patients Undergoing Surgical Aortic Valve Replacement The measurements taken from the CT scan will be used to determine the appropriate size for two types of theoretical Transcatheter Aortic Valve Replacement (TAVR) prostheses - Valvular Heart Disease | Not applicable | Recruiting | Maria Cecilia Hospital | 82 | 2025-06-25 | 2026-05-08 |
| Prehabilitation for Patients Undergoing Elective Cardiac Surgery Physical exercise, Educational program and respiration physiotherapy - Coronary Artery Disease, Valvular Heart Disease | Not applicable | Completed | Hospital Universitario 12 de Octubre | 86 | 2024-06-01 | 2026-07-15 |
| Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4) Hypothermic Cardiopulmonary Bypass, Normothermic Cardiopulmonary Bypass - Ischemic Heart Disease, Valvular Heart Disease | Not applicable | Recruiting | University of Leicester | 100 | 2024-05-20 | 2025-04-03 |
| Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer Population Transcatheter mitral valve edge-to-edge repair (M-TEER) - Mitral Regurgitation, Valvular Heart Disease | Not applicable | Recruiting | LMU Klinikum | 180 | 2024-04-01 | 2024-10-09 |
| Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions HBCR hands-off, HBCR interactive - Valvular Heart Disease | Not applicable | Recruiting | Vanderbilt University Medical Center | 240 | 2023-12-15 | 2026-09-04 |
| Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project Early diagnosis strategy - Coronary Artery Disease, Atrial Fibrillation | Not applicable | Enrolling by invitation | UMC Utrecht | 1476 | 2023-11-01 | 2024-02-23 |
| Short Term Outcomes Of Tricuspid Valve Annuloplasty Using A Flexible Band Annuloplasty Using Flexible Band - Valvular Heart Disease, Tricuspid Valve Regurgitation | Not applicable | Unknown | Assiut University | 20 | 2023-08-01 | 2023-07-07 |
| NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial TELLTALE BASILICA procedure - Valvular Heart Disease, Aortic Valve Failure | Not applicable | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 90 | 2023-02-21 | 2026-02-03 |
| Evaluation and Validation of Management Strategy for Conductive Disorders After TAVR (EVATAVI) Use of flowchart - Valvular Heart Disease | Not applicable | Completed | University Hospital, Montpellier | 250 | 2023-02-21 | 2026-06-12 |
| Hemodynamic Effect of Topical Anesthesia During Induction in Patients Undergoing Cardiac Surgery The combined topical anesthesia induction group, The routine induction group - Coronary Artery Disease, Valvular Heart Disease | Not applicable | Completed | Qianfoshan Hospital | 96 | 2022-04-20 | 2023-04-05 |
| Echocardiographic Screening of Pregnant Women During Antenatal Care Transthoracic echocardiography - Valvular Heart Disease, Rheumatic Heart Disease | Not applicable | Active not recruiting | Thomas Pilgrim | 9000 | 2021-12-01 | 2026-01-20 |
| Impact in Quality of Care of the "STructural heARt NURSE" as New Interventional Cardiology Nursing Role in Spain. STAR Nurse, Common Practice - Valvular Heart Disease, Nurse's Role | Not applicable | Unknown | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 86 | 2021-11-01 | 2020-03-24 |
| Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation No PCI - Valvular Heart Disease, Aortic Valve Stenosis | Not applicable | Active not recruiting | UMC Utrecht | 466 | 2021-10-05 | 2024-12-16 |
| Effect of Topical Anesthesia on Hemodynamics During the Induction Period in Patients Undergo Cardiac Surgery. The combined topical anesthesia induction group - Coronary Artery Disease, Valvular Heart Disease | Not applicable | Completed | Qianfoshan Hospital | 96 | 2021-03-05 | 2022-06-02 |
| Impact of a PROgram of Cardiovascular Nurse interventionS in a VALVular haEmodynamic Unit (PROCESS-VALVE) on Quality Indicators: a Quasi-experimental Ambispective Study Post-surgical nurse follow-up - Valvular Heart Disease | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 194 | 2021-02-25 | 2025-11-18 |
| Prehabilitation and Heart Valve Surgery Cycle Ergometery Training (Prehabilitation), Control Standard Group - Valvular Heart Disease | Not applicable | Completed | Riphah International University | 36 | 2021-02-01 | 2021-10-06 |
| The Effects of Intermittent Hypoxic-hyperoxic Preconditioning for Patients Undergoing Cardiopulmonary Bypass. ReOxy Cardio device, intermittent hypoxic-hyperoxic training ( IHHT), ReOxy Cardio device - Valvular Heart Disease, Aortic Arch Aneurysm | Not applicable | Completed | I.M. Sechenov First Moscow State Medical University | 115 | 2021-01-25 | 2022-12-07 |
| Whole-task Hybrid Simulation Improves Medical Student Competence in Cardiology Clerkship Tuition from a expert clinical trainer - Valvular Heart Disease | Not applicable | Completed | Royal College of Surgeons, Ireland | 77 | 2021-01-01 | 2023-06-09 |
| Effect of Trunk Stabilizing Exercises on Patients With Median Sternotomy After Heart Valve Surgery trunk stabilizing exercise, cardiac rehabilitation programe - Valvular Heart Disease | Not applicable | Unknown | Cairo University | 40 | 2020-11-21 | 2020-11-20 |
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Heart Valve Diseases (43) · Coronary Artery Disease (12) · Aortic Valve Stenosis (5) · Cardiovascular Diseases (5) · Atrial Fibrillation (4) · Heart Failure (4) · Arrhythmias, Cardiac (3) · Heart Diseases (3) · Myocardial Ischemia (3) · Cardiomyopathies (2) · Hemorrhage (2) · Hypothermia (2) · Mitral Valve Insufficiency (2) · Tricuspid Valve Insufficiency (2) · Anemia, Iron-Deficiency (1)
Heart Diseases (40) · Cardiovascular Diseases (38) · Vascular Diseases (16) · Arterial Occlusive Diseases (12) · Arteriosclerosis (12) · Coronary Disease (12) · Myocardial Ischemia (11) · Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (9) · Aortic Valve Disease (5) · Ventricular Outflow Obstruction (5) · Arrhythmias, Cardiac (3) · Body Temperature Changes (3) · Signs and Symptoms (3) · Infections (2)
Blood Specimen Collection (1) · Echocardiography (1) · Exercise (1) · Preoperative Exercise (1) · Prostheses and Implants (1) · bone wax (1)
Konkuk University Medical Center (3) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · Qianfoshan Hospital (2) · UMC Utrecht (2) · Abbott Medical Devices (1) · Assiut University (1) · Cairo University (1) · China National Center for Cardiovascular Diseases (1) · Critical Perfusion Inc. (1) · Emory University (1) · Groupe des jeunes de la filiale d'imagerie cardiovasculaire (1) · Hospital Clinic of Barcelona (1) · Hospital Universitario 12 de Octubre (1) · I.M. Sechenov First Moscow State Medical University (1) · Insel Gruppe AG, University Hospital Bern (1)
France (4) · Spain (4) · United States (4) · China (3) · Netherlands (3) · Russia (3) · South Korea (3) · Canada (2) · Egypt (2) · Germany (2) · Switzerland (2) · Belgium (1) · Brazil (1) · Denmark (1) · Finland (1)
Meng Lv, doctor (2) · Tae-Yop Kim, MD, PhD (2) · Alan Cheng, MD (1) · Brian R. Lindman, MD, MSc (1) · Claire Condron, PhD (1) · Colin Berry, PhD (1) · Emanuele Barbato, PhD (1) · Fany Lima, RN (1) · Fausto Castriota (1) · Jennifer Reed, PhD (1) · Juan B Grau Alvaro, MD (1) · Louise Sun, MD (1)
PMID 15221572, PMID 23950762, PMID 23962460, PMID 25488042, PMID 25760680, PMID 29318795, PMID 29406579, PMID 33371022, PMID 35078841, PMID 35608032, PMID 35753968, PMID 36299870, PMID 37070491, PMID 37750105, PMID 38389472, PMID 39123146, PMID 39354536, PMID 39674524, PMID 40673713, PMID 41194410, PMID 41921523, PMID 42863875
R01AG073633 (1), R01HL133667 (1)