9 completed. 9 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Completed 9 |
Follow Valvular Heart Disease: new trials by email Literature Review of Valvular Heart Disease trials Research Report on Valvular Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery Tranexamic Acid 100 MG/ML, normal saline - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | Universitas Indonesia | 132 | 2022-10-01 | 2023-02-01 |
| Sugammadex Titration in Cardiac Surgery Patients Sugammadex administration - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | University of Washington | 100 | 2022-02-01 | 2024-03-21 |
| Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery Hypertonic saline, 0.9% saline - Cardiovascular Diseases, Valvular Heart Disease | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 165 | 2018-02-27 | 2020-03-24 |
| Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery Propofol, Sevoflurane - Valvular Heart Disease, Aortic Disease | Phase 4 | Completed | Konkuk University Medical Center | 2 | 2014-05-21 | 2018-01-18 |
| Propofol Effects on Mitral Valve Annular Velocity Propofol 1.0mcg, Propofol 2.0mcg, Propofol 3.0mcg - Valvular Heart Disease, Coronary Artery Disease | Phase 4 | Completed | Konkuk University Medical Center | 40 | 2013-04-01 | 2016-04-20 |
| The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone etomidate, thiopentone - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | Mahidol University | 92 | 2011-12-01 | 2014-05-23 |
| Randomized Isoflurane and Sevoflurane Comparison in Cardiac Surgery Volatile anesthetic - Coronary Artery Disease, Valvular Heart Disease | Phase 4 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 464 | 2011-11-01 | 2015-06-08 |
| Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease Sildenafil Citrate, Placebo - Pulmonary Hypertension, Valvular Heart Disease | Phase 4 | Completed | Hospital General Universitario Gregorio Marañon | 200 | 2009-04-01 | 2016-09-23 |
| Humanalbumin, Hydroxyethylstarch and Ringer Lactate During Cardiac Surgery volume replacement, Humanalbumin 5% - Valvular Heart Disease, Coronary Artery Disease | Phase 4 | Completed | Medical University of Vienna | 240 | 2006-03-01 | 2015-04-08 |
Heart Valve Diseases (9) · Coronary Artery Disease (6) · Aortic Diseases (2) · Blood Loss, Surgical (1) · Cardiovascular Diseases (1) · Heart Failure (1) · Hypertension, Pulmonary (1) · Postoperative Hemorrhage (1)
Heart Diseases (9) · Cardiovascular Diseases (8) · Vascular Diseases (8) · Arterial Occlusive Diseases (6) · Arteriosclerosis (6) · Coronary Disease (6) · Myocardial Ischemia (6) · Hemorrhage (1) · Hypertension (1) · Intraoperative Complications (1) · Lung Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Postoperative Complications (1) · Respiratory Tract Diseases (1)
Propofol (2) · Saline Solution (2) · Etomidate (1) · HES 130-0.4 (1) · Hydroxyethyl Starch Derivatives (1) · Saline Solution, Hypertonic (1) · Sevoflurane (1) · Sildenafil Citrate (1) · Thiopental (1) · Tranexamic Acid (1)
Konkuk University Medical Center (2) · Hospital General Universitario Gregorio Marañon (1) · Insel Gruppe AG, University Hospital Bern (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Mahidol University (1) · Medical University of Vienna (1) · Universitas Indonesia (1) · University of Washington (1)
South Korea (2) · Austria (1) · Canada (1) · Indonesia (1) · Spain (1) · Switzerland (1) · Thailand (1) · United States (1)
Eva M Base, MD (1) · Javier Bermejo, MD, PhD (1) · Joerg C Schefold, MD (1) · Manee Raksakietisak, MD (1) · Philip M Jones, MD MSc (1) · Seong-Hyop Kim, M.D, Ph.D (1) · T. Andrew Bowdle, MD, PhD (1) · Tae-yop Kim, MD, PhD (1)
PMID 16438759, PMID 17218108, PMID 26437535, PMID 27465213, PMID 29281101, PMID 30908754, PMID 31020819, PMID 31200756, PMID 33399006