20 completed, 3 unknown, 2 terminated, 2 withdrawn. 29 Phase 1, 14 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Completed 20, Unknown 3, Terminated 2, Withdrawn 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 14 | Completed 11, Terminated 2, Not yet recruiting 1 |
Follow Surgery: new trials by email Literature Review of Surgery trials Research Report on Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Research on the Efficacy and Mechanism of Shouhui Tongbian Capsules in Treating Postoperative Constipation of Benign Anal and Rectal Diseases Based on Gut Microbiota Analysis Shouhui Tongbian Capsules, Lactulose Oral Solution Control Group - Intestinal Flora, Anorectal Diseases | Phase 1 / Phase 2 | Not yet recruiting | China-Japan Friendship Hospital | 120 | 2026-08-01 | 2026-07-22 |
| Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries. Lidocaine Intravenous Infusion, Lidocaine and ketamine, lidocaine and dexmedetomidine infusion - Pelvic Cancer, Abdominal Cancer | Phase 1 | Completed | Alexandria University | 45 | 2023-09-24 | 2024-10-08 |
| Tissue Inhibitor of Metalloproteinases 2 Level in Patients Undergoing Cardiac Surgery TIMP2 level - Acute Kidney Injury, Extracorporeal Circulation; Complications | Phase 1 / Phase 2 | Completed | Wuhan University | 100 | 2023-07-22 | 2025-03-12 |
| Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis Tranexamic acid - Surgery, Postoperative Blood Loss | Phase 1 | Recruiting | Vanderbilt University Medical Center | 60 | 2023-04-01 | 2026-05-07 |
| The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear Glycerol - Tympanosclerosis, Thickened Ears | Phase 1 | Withdrawn | Nova Scotia Health Authority | 2022-10-01 | 2024-08-21 | |
| ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery IT Injection, ESP Block - Surgery | Phase 1 / Phase 2 | Terminated | Indiana University | 116 | 2022-01-27 | 2026-03-02 |
| Thyroid Cancer and Central Lymph Node Metastases Detection Using Bevacizumab-IRDye800CW Bevacizumab-IRDye800CW - Thyroid Carcinoma, Surgery | Phase 1 | Completed | University Medical Center Groningen | 20 | 2021-11-29 | 2024-08-22 |
| A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery. Dose Response Curve Placebo, Dose Response Curve N-acetylcysteine 50 mg/kg, Dose Response Curve N-acetylcysteine 100 mg/kg - Surgery | Phase 1 / Phase 2 | Completed | Medical University of South Carolina | 50 | 2021-01-20 | 2023-02-14 |
| A Pilot Randomized Controlled Trial for Feasibility of Administering an AR Game to Postoperative Pediatric Cancer Patients ARISE with AR, ARISE without AR - Pediatric Cancer, Surgery | Phase 1 | Unknown | ALTality, Inc. | 20 | 2021-01-13 | 2021-08-16 |
| Effect of Perampanel on Peritumoral Hyperexcitability in HGG Perampanel, Standard of Care - Glioma, Malignant, Surgery | Phase 1 / Phase 2 | Completed | Dana-Farber Cancer Institute | 12 | 2020-11-05 | 2024-08-05 |
| Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery Bevonescein - Parotid Neoplasm, Thyroid Neoplasms | Phase 1 / Phase 2 | Completed | Alume Biosciences, Inc. | 27 | 2020-06-18 | 2025-05-08 |
| Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers CT-044 - Pain, Acute, Acute Pain | Phase 1 | Completed | Lotus Clinical Research, LLC | 10 | 2020-02-18 | 2020-06-12 |
| Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers CT-044 HCl - Acute Pain, Pain, Acute | Phase 1 | Unknown | Lotus Clinical Research, LLC | 21 | 2019-12-04 | 2020-07-23 |
| The Safety and Feasibility of Transoral Endoscopic Thyroidectomy Vestibular Approach TOETVA - Thyroid Diseases, Surgery | Phase 1 | Unknown | University Health Network, Toronto | 15 | 2019-12-01 | 2021-04-13 |
| AIN Transfer for Cubital Tunnel Syndrome nerve transfer - Nerve Injury, Surgery | Phase 1 / Phase 2 | Completed | University of Alberta | 65 | 2019-01-01 | 2023-04-06 |
| Caudal Ketamine-bupivacaine More Effective Than Bupivacaine-saline Ketamine - Surgery, Pediatric Surgery | Phase 1 | Completed | Egymedicalpedia | 60 | 2018-09-01 | 2022-09-10 |
| Validation of ICG to Identify the Urethra During Rectal Surgery Indocyanine Green Solution - Urethra Injury, Rectal Cancer | Phase 1 / Phase 2 | Terminated | Oxford University Hospitals NHS Trust | 5 | 2017-07-11 | 2019-08-13 |
| Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery Dexamethasone, Bupivacaine, Bilateral Pudendal Nerve Block - Pelvic Organ Prolapse, Surgery | Phase 1 / Phase 2 | Completed | Lauren Giugale, MD | 79 | 2017-06-01 | 2020-03-09 |
| IS-001 Injection Phase-1 Safety, Tolerance and Pharmacokinetics IS-001, da Vinci® Si/Xi Surgical System - Hysterectomy, Surgery | Phase 1 | Completed | Intuitive Surgical | 24 | 2016-12-01 | 2018-03-05 |
| Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair Adductor Canal Block, Morphine Patient Controlled Analgesia - Anesthesia, Stress, Physiological | Phase 1 | Withdrawn | Pontificia Universidad Catolica de Chile | 2016-09-01 | 2021-03-15 |
Showing 20 of 29. Sign in to see all of them.
Acute Pain (2) · Anxiety Disorders (2) · Neoplasms (2) · Rectal Neoplasms (2) · Thyroid Neoplasms (2) · Acute Kidney Injury (1) · Constipation (1) · Cubital Tunnel Syndrome (1) · Glioma (1) · Head and Neck Neoplasms (1) · Pain (1) · Pain, Postoperative (1) · Parotid Neoplasms (1) · Pelvic Neoplasms (1) · Pelvic Organ Prolapse (1)
Neoplasms (7) · Pathological Conditions, Signs and Symptoms (7) · Neoplasms by Site (6) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Digestive System Diseases (3) · Endocrine System Diseases (3) · Gastrointestinal Diseases (3) · Intestinal Diseases (3) · Pain (3) · Colorectal Neoplasms (2) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Gastrointestinal Neoplasms (2) · Head and Neck Neoplasms (2)
Ketamine (2) · Sodium Chloride (2) · chlorhexidine gluconate (2) · Analgesia, Patient-Controlled (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Cefazolin (1) · Dexamethasone (1) · Glycerol (1) · IS 001 (1) · Injections, Spinal (1) · Lidocaine (1) · Massage (1) · Nerve Transfer (1) · Saline Solution (1)
Lotus Clinical Research, LLC (2) · Medline Industries (2) · ALTality, Inc. (1) · Alexandria University (1) · Alume Biosciences, Inc. (1) · Boston Medical Center (1) · China-Japan Friendship Hospital (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dana-Farber Cancer Institute (1) · Egymedicalpedia (1) · Indiana University (1) · Intuitive Surgical (1) · Isfahan University of Medical Sciences (1) · King Faisal University (1)
United States (12) · China (3) · Canada (2) · Egypt (2) · Belgium (1) · Chile (1) · Denmark (1) · Iran (1) · Netherlands (1) · Saudi Arabia (1) · United Kingdom (1)
Aaron S Fink, MD (1) · Alexander J Barna, MPH (1) · Amy McCutchan, MD (1) · Bashir M Hamid, MD (1) · Christina York (1) · David P Morris, MD (1) · Fernando Altermatt, MD (1) · Jaclyn S Lee, MD (1) · Jae Eun Choi (1) · Jamie Sinton, MD (1) · Jean-Pascal Machiels, PhD (1) · Jennifer E Rosen, MD, FACS (1) · Jesse D Pasternak, MD (1) · Jianping Wang, MD (1) · Jong Woo Lee, MD, PhD (1)
PMID 34145168, PMID 19216667, PMID 19455368, PMID 19536029, PMID 19586079, PMID 19632618, PMID 19715815, PMID 20510800, PMID 20562609, PMID 24522223, PMID 25532706, PMID 26310534, PMID 31215195, PMID 33278291, PMID 37877260, PMID 39499201, PMID 40042121, PMID 40595556
P50CA165962 (1), R42DA050365 (1)