33 completed, 8 unknown, 3 recruiting, 2 withdrawn. 19 Not applicable, 11 Phase 2, 10 Phase 4, 7 Phase 3, 4 Phase 1.
Follow Glycerol: new trials by email Literature Review of Glycerol trials Research Report on Glycerol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lactate and Glycerol Contribution to Gluconeogenesis Glycerol, Lactate, Glucose - Type 2 Diabetes, Obesity | Not applicable | Not yet recruiting | Rutgers, The State University of New Jersey | 48 | 2026-07-01 | 2025-12-02 |
| Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease Preservative Free Polyethylene glycol 400 0.25%, Propylene Glycol (0.6%), Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5% - Dry Eye Disease (DED) | Phase 4 | Recruiting | Andover Research Eye Institute | 60 | 2026-06-03 | 2026-06-30 |
| Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain Intravenous oxytocin, Intravenous placebo, Intranasal oxytocin - Pain, Acute | Phase 2 | Completed | Wake Forest University Health Sciences | 24 | 2025-11-05 | 2026-06-30 |
| Effects of Beverage Volume, Glycerol Concentration, and Sodium Concentration on Fluid Balance in Healthy Euhydrated Men and Women at Rest Placebo beverage, kiwi-strawberry flavor, Electrolyte solution without glycerol beverage 1, Electrolyte solution without glycerol beverage 2 - Fluid Balance | Not applicable | Completed | PepsiCo Global R&D | 60 | 2025-07-18 | 2026-09-21 |
| Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT) Allogeneic Microbiota in Glycerol (9%) (AMG) - Multi-Drug Resistant Organism Colonization | Phase 2 | Recruiting | Emory University | 60 | 2025-01-13 | 2025-11-05 |
| Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats Lactoferrin, iron, MDA, TAC, and GSH - Rhabdomyolysis | Phase 4 | Completed | Aswan University Hospital | 24 | 2024-11-01 | 2025-07-04 |
| Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen PEG 3350, PEG-3350 with electrolytes, Glycerin - Constipation | Phase 4 | Recruiting | Indiana University | 65 | 2023-06-08 | 2026-08-18 |
| Sentinel Cohort REACT Allogeneic Microbiota in Glycerol (10%) (AMG) - Multi-Drug Resistant Organism | Phase 1 | Completed | Emory University | 10 | 2023-04-24 | 2024-03-28 |
| Assessing the Efficacy of CREWS01 to Decrease Usage of Rescue Inhalers in Moderate to Severe Asthmatic Adults Antipyrine-benzocaine otic solution, Glycerin with Oxyquinoline Sulfate - Asthma | Phase 2 | Unknown | Global United Pharmaceutical Corporation | 50 | 2023-04-01 | 2023-02-08 |
| A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Glycerin 0.2%/Hypromellose 0.2%/Peg 1%/Soln,Oph,Ud - Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy | Phase 2 / Phase 3 | Unknown | Wills Eye | 80 | 2023-02-06 | 2024-07-30 |
| Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops glycerin 0.7%/PEG 400 0.3%, polyethylene glycol 400 0.4%/propylene glycol 0.3% - Dry Eye Disease | Not applicable | Completed | Calm Water Therapeutics LLC | 34 | 2022-12-12 | 2023-09-06 |
| The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear Glycerol - Tympanosclerosis, Thickened Ears | Phase 1 | Withdrawn | Nova Scotia Health Authority | 2022-10-01 | 2024-08-21 | |
| Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes PLACEBO, GLYCEROL - Performance Enhancing Product Use, Change, Body Weight | Not applicable | Completed | Francisco Javier MartÃnez Noguera | 4 | 2022-02-10 | 2022-03-25 |
| Monitoring of the Bone Free Flaps With Microdialysis glucose measurement, lactacte measurement, pyruvate measurement - Flap Necrosis | Not applicable | Unknown | Centre Hospitalier Universitaire, Amiens | 40 | 2019-07-22 | 2024-07-10 |
| The Impact of Ashwagandha on Perceived Stress, Sleep and Food Cravings in College Students Ashwagandha, Placebo - Stress, Sleep | Phase 2 | Completed | University of Colorado, Colorado Springs | 60 | 2019-05-29 | 2022-06-24 |
| Prevention of Bleaching Induced Sensitivity neutral sodium fluoride, ACP-CCP gel, nano-hydroxyapatite solution - Tooth Bleaching, Tooth Sensitivity | Not applicable | Completed | Medipol University | 64 | 2019-01-07 | 2021-04-28 |
| A Nicotine Pharmacokinetics and Smoking Behaviour Study Examining Cigarette Ingredients Reference cigarette, Cigarette with carob bean extract, Cigarette with cocoa powder - Healthy Volunteers, Smoking | Not applicable | Completed | British American Tobacco (Investments) Limited | 40 | 2017-09-12 | 2022-12-07 |
| A Study to Measure the Sun Protection Factor (SPF) and Ultraviolet-A Protection Factor (UVAPF) of Four Developmental Sunscreen Formulations NGBUV000A, (Expected SPF 30), NGBUV000B, (Expected SPF 30), NGBUV000C, (Expected SPF 30) - Sunscreening Agents | Not applicable | Completed | GlaxoSmithKline | 8 | 2017-06-21 | 2019-07-22 |
| Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity 5% Sodium Fluoride Varnish, 15% Nanohydroxyapetite paste, Glycerol - Dentin Hypersensitivity | Phase 4 | Completed | Riyadh Colleges of Dentistry and Pharmacy | 63 | 2016-10-01 | 2020-03-11 |
| Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique Glycerol - Trigeminal Neuralgia, Headache Disorders | Phase 1 / Phase 2 | Terminated | Norwegian University of Science and Technology | 1 | 2016-05-01 | 2019-03-27 |
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Dry Eye Syndromes (7) · Diabetes Mellitus (4) · Constipation (3) · Dentin Sensitivity (2) · Insulin Resistance (2) · Keratoconjunctivitis Sicca (2) · Obesity (2) · Smoking (2) · Acute Pain (1) · Agnosia (1) · Asthma (1) · Body Temperature Changes (1) · Body Weight Changes (1) · Carnitine Palmitoyltransferase II Deficiency, Late-Onset (1) · Dermatitis (1)
Allergan (5) · Calm Water Therapeutics LLC (2) · Emory University (2) · Ferring Pharmaceuticals (2) · Andover Research Eye Institute (1) · Aswan University Hospital (1) · Beatrice Olsson Duse (1) · Bispebjerg Hospital (1) · British American Tobacco (Investments) Limited (1) · Cairo University (1) · Centre Hospitalier Universitaire, Amiens (1) · Francisco Javier MartÃnez Noguera (1) · GlaxoSmithKline (1) · Global United Pharmaceutical Corporation (1) · Glostrup University Hospital, Copenhagen (1)
United States (23) · France (3) · China (2) · Denmark (2) · Saudi Arabia (2) · United Kingdom (2) · Canada (1) · Egypt (1) · Estonia (1) · Germany (1) · Lithuania (1) · Malawi (1) · Mexico (1) · Norway (1) · Poland (1)
Agneta L. Sunehag (1) · Anders Clemmensen, MD (1) · Ankit Shah, MD (1) · Benin Dikmen, Dr. (1) · Cesar R. Ramos-Remus, M.D., MSc (1) · Dalia N AlHarith (1) · David Fleischer, MD (1) · David P Morris, MD (1) · Dina N Abbas, MD (1) · Dorte Nellemann Thornit, MD (1) · Elizabeth M Molyneux, FRCPCH (1) · Eric Gardiner, PhD, (1) · Erling A Tronvik, PhD, MD (1)
PMID 15173799, PMID 18973181, PMID 20042642, PMID 22639293, PMID 23265698, PMID 24513806, PMID 25656999, PMID 25659956, PMID 26424091, PMID 28157063, PMID 32568464, PMID 33006765, PMID 34704970, PMID 35984870, PMID 35984871, PMID 40705333, PMID 42568743
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