395 completed, 179 unknown, 164 recruiting, 65 active not recruiting. 280 Not applicable, 210 Phase 2, 102 Phase 1, 40 Phase 3, 26 Phase 4.
Follow Thyroid Neoplasms: new trials by email Literature Review of Thyroid Neoplasms trials Research Report on Thyroid Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mapping Patient Decision-making in Thyroid Cancer Decision navigation tool - Thyroid Cancer | Not applicable | Not yet recruiting | University of California, Los Angeles | 50 | 2028-04-01 | 2026-07-24 |
| Pre-Clinic Visit Online Education for Thyroid Cancer THRIVE, ACS "After a Thyroid Cancer Diagnosis" Flyer - Thyroid Cancer | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 60 | 2027-08-01 | 2026-09-01 |
| Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules Diagnostic DNA Methylation Signature - Thyroid Gland Nodule | Recruiting | City of Hope Medical Center | 22 | 2027-01-01 | 2026-06-02 | |
| Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer Dabrafenib, Trametinib, Pembrolizumab - Anaplastic Thyroid Carcinoma, Thyroid Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-12-31 | 2026-10-21 |
| Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial Internet-Based Intervention, Interview, Questionnaire Administration - Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 142 | 2026-12-01 | 2026-10-15 |
| 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer 68Ga-DOTA-TATE PET Scan, Amino acid infusions, 177Lu-DOTA-EB-TATE - Thyroid Cancer | Phase 1 / Phase 2 | Not yet recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 18 | 2026-11-18 | 2026-11-13 |
| Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP) Sacituzumab Tirumotecan - Recurrent Adenoid Cystic Carcinoma, Adenoid Cystic Carcinoma Metastatic | Phase 2 | Not yet recruiting | National Cancer Centre, Singapore | 68 | 2026-11-01 | 2026-07-15 |
| Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma | Not yet recruiting | Marmara University | 90 | 2026-11-01 | 2026-11-02 | |
| Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery Transcartilage needle electrode recording, Endotracheal tube surface electrode recording - Thyroid Diseases, Recurrent Laryngeal Nerve Injury | Not applicable | Not yet recruiting | Marmara University | 100 | 2026-11-01 | 2026-10-30 |
| Bethesda Classification and Risk Stratification in Differentiated Thyroid Carcinoma Differentiated Thyroid Carcinoma, Papillary Thyroid Carcinoma | Not yet recruiting | Assiut University | 100 | 2026-10-26 | 2026-10-05 | |
| A Study of Selpercatinib (LY3527723) in Participants With Rearranged During Transfection (RET)-Altered Cancers in India Selpercatinib - Thyroid Neoplasms, Carcinoma, Non-Small-Cell Lung | Phase 4 | Not yet recruiting | Eli Lilly and Company | 30 | 2026-10-01 | 2026-10-08 |
| Educational Videos for Thyroid Surgery Patient Thyroid Surgery Educational Video - Thyroid Cancer, Thyroid Nodule | Not applicable | Not yet recruiting | West China Hospital | 400 | 2026-10-01 | 2026-09-16 |
| Head and Neck Cancer Strategies Head and Neck Cancer (H&N), Thyroid Cancer | Enrolling by invitation | Aarhus University Hospital | 1500 | 2026-10-01 | 2026-11-02 | |
| Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial Personalised treatment - Thyroid Cancer Stage IV, Anaplastic Thyroid Cancer | Phase 1 | Recruiting | Radboud University Medical Center | 10 | 2026-10-01 | 2026-10-28 |
| MRG003 Added to Ongoing Treatment After Progression in EGFR-Positive Advanced Thyroid Cancer Becotatug Vedotin (MRG003), Lenvatinib, Anti-PD-1 Inhibitor (Continuation of Prior Treatment) - Thyroid Cancer, Tumor | Phase 2 | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 39 | 2026-09-20 | 2026-10-14 |
| Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University Hospitals Papillary Thyroid Carcinoma, Thyroid Cancer | Not yet recruiting | Sohag University | 30 | 2026-09-16 | 2026-09-16 | |
| Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy WeChat-supported Neck Rehabilitation Exercise, Standardized Postoperative Care and Video Education - Thyroid Diseases, Thyroid Cancer | Not applicable | Recruiting | Shanghai 6th People's Hospital | 200 | 2026-09-09 | 2026-09-10 |
| Thyroid Health Outcomes Registry for Surgery Thyroid Diseases, Thyroid Neoplasms | Not yet recruiting | Pirogov Russian National Research Medical University | 3000 | 2026-09-01 | 2026-09-10 | |
| A Novel Ultrasound Probe for Thyroid Imaging and Machine Learning Thyroid ultrasound - Thyroid Nodules, Thyroid Abnormalities | Not applicable | Recruiting | Sound Blade Medical Inc. | 30 | 2026-09-01 | 2026-09-01 |
| Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy Euthyrox (levothyroxine), Cytomel (liothyronine) - Differentiated Thyroid Cancer, Thyroid Cancer | Not yet recruiting | University Medical Center Groningen | 40 | 2026-09-01 | 2026-02-10 |
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Thyroid Nodule (187) · Thyroid Cancer, Papillary (185) · Breast Neoplasms (70) · Head and Neck Neoplasms (65) · Thyroid Diseases (65) · Adenocarcinoma, Follicular (62) · Neoplasms (59) · Melanoma (57) · Carcinoma, Non-Small-Cell Lung (56) · Carcinoma, Medullary (51) · Ovarian Neoplasms (48) · Pancreatic Neoplasms (48) · Prostatic Neoplasms (48) · Colorectal Neoplasms (47)
Endocrine System Diseases (936) · Neoplasms by Site (933) · Endocrine Gland Neoplasms (931) · Neoplasms (882) · Head and Neck Neoplasms (876) · Thyroid Diseases (876) · Neoplasms by Histologic Type (331) · Neoplasms, Glandular and Epithelial (300) · Carcinoma (280) · Adenocarcinoma (250) · Adenocarcinoma, Papillary (184) · Neoplasms, Nerve Tissue (130) · Neoplasms, Germ Cell and Embryonal (129) · Neuroectodermal Tumors (129)
Iodine-131 (24) · Magnetic Resonance Spectroscopy (21) · lenvatinib (20) · Thyroidectomy (17) · Thyrotropin Alfa (15) · trametinib (15) · Sorafenib (13) · dabrafenib (13) · pembrolizumab (13) · Radiofrequency Ablation (11) · Surgical Procedures, Operative (11) · Transurethral Resection of Prostate (10) · selpercatinib (10) · Paclitaxel (9) · Thyroxine (9)
National Cancer Institute (NCI) (42) · Memorial Sloan Kettering Cancer Center (25) · Fujian Medical University (17) · M.D. Anderson Cancer Center (17) · Assiut University (16) · Fudan University (15) · Yonsei University (13) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (11) · Chinese PLA General Hospital (10) · Mayo Clinic (9) · National Taiwan University Hospital (9) · Seoul National University Hospital (9) · Eli Lilly and Company (8) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (8) · University Health Network, Toronto (8)
United States (318) · China (183) · France (73) · Italy (72) · South Korea (70) · Canada (47) · Spain (38) · United Kingdom (38) · Germany (32) · Netherlands (32) · Denmark (30) · Turkey (Türkiye) (29) · Australia (28) · Taiwan (24) · Israel (22)
Yukun Luo (5) · Joanna Klubo-Gwiezdzinska, M.D. (4) · Kiyohiko Mabuchi, M.D. (4) · Naris Nilubol, M.D. (4) · Alan Ho, MD, PhD (3) · Douglas Van Nostrand, MD (3) · Electron Kebebew, MD (3) · Eric Sherman, MD (3)
PMID 37934000, PMID 40341199, PMID 40668552, PMID 27240885, PMID 31838007, PMID 32612576, PMID 33570641, PMID 33720068, PMID 36657661, PMID 37171634, PMID 37816266, PMID 40086048, PMID 11442004, PMID 11875733, PMID 12225640, PMID 12541136, PMID 12660642, PMID 12800205, PMID 14557134, PMID 14652672, PMID 14668957, PMID 15068625, PMID 15319714, PMID 15551359, PMID 15588952, PMID 15855141, PMID 16125070, PMID 16339287, PMID 16384850, PMID 16400382, PMID 16511940, PMID 16522694, PMID 16964393, PMID 17131394, PMID 17143968, PMID 17278943, PMID 17299648, PMID 17885154, PMID 17985341, PMID 17985985, PMID 18281176, PMID 18323549, PMID 18366712, PMID 18382668, PMID 18438123, PMID 18469262, PMID 18596272, PMID 18854394, PMID 19017880, PMID 19022998
2016 (5), P30CA015083 (5), 2023 (4), N01CM62207 (4), 2015 (3), 2019 (3), N01CM00099 (3), N01CM62201 (3), N01CM62206 (3), P30CA008748 (3), P30CA016672 (3), 2005 (2), 2014 (2), 2018 (2), 2025 (2)