14 completed, 13 recruiting, 7 unknown, 4 not yet recruiting. 17 Not applicable, 13 Phase 3, 3 Phase 2, 3 Phase 4, 1 Phase 1.
Follow Stroke, Acute Ischemic: new trials by email Literature Review of Stroke, Acute Ischemic trials Research Report on Stroke, Acute Ischemic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke MLC901, Standard treatment for acute ischemic stroke - Stroke, Stroke, Acute Ischemic | Phase 4 | Recruiting | EVD Pharmacy and Medical Company Limited | 80 | 2026-09-10 | 2026-10-20 |
| ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 Tenecteplase or Alteplase- depending upon availability at each treating centre, Control - Stroke, Acute Ischemic, Endovascular Thrombectomy | Phase 3 | Recruiting | University of Calgary | 1500 | 2026-08-11 | 2026-10-21 |
| INtra-arterial AltEplase folloWing successfuL reperfusIoN After mEchanical Thrombectomy Alteplase, Endovascular thrombectomy - Stroke, Acute Ischemic, Large Vessel Occlusion | Phase 3 | Recruiting | 115 People's Hospital | 416 | 2026-08-01 | 2026-09-25 |
| Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT) Isosorbide Mononitrate, Butylphthalide, Isosorbide Mononitrate Placebo - Stroke, Lacunar, Stroke, Acute Ischemic | Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 3156 | 2025-12-01 | 2025-11-26 |
| Intravenous rhTNK-tPA Before Stroke Thrombectomy in the Extended Time Window Intravenous rhTNK-tPA, Intravenous placebo, Endovascular thrombectomy - Stroke, Acute Ischemic | Phase 3 | Recruiting | Xinqiao Hospital of Chongqing | 820 | 2025-10-21 | 2025-12-31 |
| Early Endovascular Treatment in Isolated Internal Carotid Artery Occlusion Endovascular treatment, The best medical treatment - Stroke, Acute Ischemic | Not applicable | Recruiting | Sir Run Run Shaw Hospital | 140 | 2025-06-01 | 2025-06-12 |
| Intra-Arterial Thrombolysis After SUCCESSful Reperfusion in Anterior Circulation Ischemic Stroke Intra-arterial infusion of Alteplase - Stroke, Acute Ischemic | Phase 3 | Recruiting | Central Hospital, Nancy, France | 626 | 2025-06-01 | 2025-06-05 |
| Immediate Angioplasty For Acute Ischemic Stroke With Severe Intracranial Atherosclerotic Stenosis Immediate angioplasty - Stroke, Acute Ischemic | Not applicable | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 412 | 2025-05-08 | 2025-05-25 |
| IntraCranial Atherosclerosis Related Large-vessel Occlusion Treated With Urgent Stenting (ICARUS) Intracranial stenting, Continuation of conventional endovascular therapy (EVT) - Stroke, Stroke, Acute Ischemic | Not applicable | Recruiting | University Hospital, Basel, Switzerland | 498 | 2025-03-31 | 2025-12-17 |
| Lesion Network MApping Navigated Continuous Theta-burst STimulation for Motor REcovery in Acute Ischemic Stroke Continuous Theta-burst Stimulation, Sham stimulation - Stroke, Acute Ischemic | Phase 2 | Completed | Beijing Tiantan Hospital | 60 | 2024-10-21 | 2026-04-08 |
| Tirofiban for Successful Endovascular Stroke Thrombectomy Intraarterial and intravenous tirofiban, Intraarterial and intravenous placebo - Stroke, Acute Ischemic | Phase 2 / Phase 3 | Not yet recruiting | Zhongming Qiu | 712 | 2024-07-31 | 2024-05-16 |
| Endovascular Treatment for eXtra-Large Ischemic Stroke Medical management, Endovascular thrombectomy - Stroke, Acute Ischemic | Not applicable | Recruiting | Zhongming Qiu | 286 | 2024-06-16 | 2025-12-26 |
| Low-Frequency REpetitive TRanscranial Magnetic Stimulation Combined With Endovascular Treatment in ACute Ischemic StrokE LF-rTMS, Sham stimulation - Stroke, Acute Ischemic | Not applicable | Completed | Beijing Tiantan Hospital | 60 | 2024-05-25 | 2026-04-08 |
| Community Health Worker Assisted Task Specific and Cognitive Therapy at Home With Exposure After Stroke CATCHES - Stroke, Acute Ischemic | Not applicable | Completed | Columbia University | 30 | 2024-05-09 | 2026-04-20 |
| The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction Y-3 ICO injection, Y-3 intravenous injection, Conventional treatment - Stroke, Acute Ischemic, Blood-Brain Barrier | Not applicable | Recruiting | yilong Wang | 134 | 2024-04-22 | 2025-01-28 |
| Cerebroprotective Effect of Melatonin in Stroke Melatonin 10 MG, Placebo - Stroke, Acute Ischemic, Strokes Thrombotic | Phase 3 | Unknown | Coordinación de Investigación en Salud, Mexico | 100 | 2024-03-01 | 2024-03-05 |
| Trendelenburg Position for Acute Anterior Circulation Ischemic Stroke With Large Artery Atherosclerosis Etiology (HOPES 3) head-down position - Stroke, Acute Ischemic | Not applicable | Recruiting | General Hospital of Shenyang Military Region | 600 | 2024-01-10 | 2026-04-27 |
| Effectiveness of Yangxue Qingnao Granules in Preventing Post Thrombolytic Hemorrhage Transformation in Patients With Acute Cerebral Infarction Yangxue Qingnao Granules - Stroke, Acute Ischemic | Not applicable | Unknown | Peking University Third Hospital | 60 | 2024-01-01 | 2024-04-03 |
| Role of Hypothermia in Endovascular Stroke Thrombectomy hypothermia, thrombectomy - Stroke, Acute Ischemic | Not applicable | Not yet recruiting | Xinqiao Hospital of Chongqing | 200 | 2023-12-01 | 2023-10-31 |
| Intravenous Tirofiban Versus Thrombolysis Before Mechanical Thrombectomy in Stroke Tirofiban, Thrombolysis - Stroke, Acute Ischemic | Phase 2 / Phase 3 | Completed | Xinqiao Hospital of Chongqing | 1014 | 2023-11-28 | 2026-09-14 |
Showing 20 of 41. Sign in to see all of them.
Ischemic Stroke (41) · Stroke (8) · Cerebral Small Vessel Diseases (2) · Hypertension (2) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Cardiovascular Diseases (1) · Cerebral Hemorrhage (1) · Cognitive Dysfunction (1) · Dyslipidemias (1) · Encephalitis (1) · Hypothermia (1) · Hypoxia-Ischemia, Brain (1) · Intracranial Arteriosclerosis (1) · Intracranial Hemorrhages (1)
Brain Diseases (41) · Central Nervous System Diseases (41) · Cerebrovascular Disorders (41) · Nervous System Diseases (41) · Vascular Diseases (41) · Cardiovascular Diseases (40) · Stroke (33) · Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (4) · Hemorrhage (2) · Infarction (2) · Ischemia (2) · Necrosis (2) · Signs and Symptoms (2) · Arterial Occlusive Diseases (1)
Tissue Plasminogen Activator (4) · Fibrinolytic Agents (2) · Tirofiban (2) · 3-n-butylphthalide (1) · Albumins (1) · Ezetimibe (1) · Focused Assessment with Sonography for Trauma (1) · Head-Down Tilt (1) · Infusions, Intra-Arterial (1) · Melatonin (1) · Neuroaid (1) · Practice Management, Medical (1) · Rosuvastatin Calcium (1) · Tenecteplase (1) · Thrombectomy (1)
Beijing Tiantan Hospital (4) · Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Tianjin Huanhu Hospital (3) · Xinqiao Hospital of Chongqing (3) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Zhongming Qiu (2) · 115 People's Hospital (1) · Assiut University (1) · Boston Medical Center (1) · Brigham and Women's Hospital (1) · Central Hospital, Nancy, France (1) · Columbia University (1) · Coordinación de Investigación en Salud, Mexico (1) · EVD Pharmacy and Medical Company Limited (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1)
China (17) · United States (4) · Spain (3) · Canada (2) · Finland (2) · South Korea (2) · Switzerland (2) · Vietnam (2) · Australia (1) · Colombia (1) · France (1) · Germany (1) · Italy (1) · Mexico (1) · Norway (1)
Amar Dhand, MD, PhD (1) · Ana Morales, MD (1) · Angel Chamorro, MD, PhD (1) · Bijoy K Menon, MD (1) · Boris Pabon, MD (1) · Chenghua Xu (1) · Chong Zheng (1) · Congguo Yin (1) · Congguo Yin, Doctor (1) · Craig Anderson, MD (1) · Daojun Hong, MD (1) · Guangxiong Yuan (1)
PMID 39500603, PMID 33464335, PMID 35143603, PMID 35943471, PMID 37222709, PMID 38296589, PMID 38753954, PMID 39357896, PMID 39403266, PMID 40174223, PMID 40414088, PMID 40461153, PMID 40721316, PMID 40921621, PMID 41339082, PMID 41778584, PMID 41974577, PMID 42096239, PMID 42262770, PMID 42265863, PMID 42422957, PMID 42439416, PMID 42858287
2023 (2), P30AG064198 (1), P30AG064199 (1)