190 completed, 47 unknown, 39 recruiting, 13 not yet recruiting. 65 Phase 2, 50 Phase 3, 41 Not applicable, 36 Phase 4, 32 Phase 1.
Follow Encephalitis: new trials by email Literature Review of Encephalitis trials Research Report on Encephalitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-11-16 | 2026-11-05 | |
| [11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction [11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan - Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild | Phase 1 | Not yet recruiting | Stony Brook University | 18 | 2026-10-01 | 2026-10-02 |
| Clinical Evaluation of a Novel DAB Chromogenic Tissue-Based Assay for Detecting Anti-GABABR Antibodies Autoimmune Encephalitis, Anti-NMDAR Encephalitis | Not yet recruiting | Third Affiliated Hospital, Sun Yat-Sen University | 300 | 2026-10-01 | 2026-10-05 | |
| Early Neurological Outcome in Pediatric Encephalitis Encephalitis, Brain Diseases | Not yet recruiting | Assiut University | 88 | 2026-09-20 | 2026-09-22 | |
| Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury: A Clinical Development and Evaluation Study TAU + Group Therapy (EAET), Treatment as Usual (TAU) - Aquired Brain Injury, Stroke | Not applicable | Recruiting | Uppsala University | 110 | 2026-09-15 | 2026-10-01 |
| Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex BV100 with 50 mg polymyxin B plus ceftazidime/avibactam, BV100 with 50 mg polymyxin B plus cefiderocol, Best Available Therapy (BAT) - Ventilator Associated Bacterial Pneumonia (VABP), Hospital Acquired Bacterial Pneumonia (HABP) | Phase 2 | Not yet recruiting | BioVersys AG | 120 | 2026-07-01 | 2026-02-24 |
| Efgartigimod in Anti-NMDA Receptor Encephalitis. Efgartigimod Alfa - Encephalitis Autoimmune | Phase 2 | Recruiting | Beijing Tongren Hospital | 20 | 2026-06-25 | 2026-09-16 |
| Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study Brincidofovir - Progressive Multifocal Leukoencephalopathy | Phase 2 | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2026-06-05 | 2026-07-22 |
| Risk of Progressive Multifocal Leukoencephalopathy Among Patients With Multiple Sclerosis Exposed to Zeposia Ozanimod - Multiple Sclerosis, Progressive Multifocal Leukoencephalopathy | Recruiting | Bristol-Myers Squibb | 15 | 2026-06-04 | 2026-07-29 | |
| A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease ART5803, ART5803-Cohort D - Anti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE), Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease | Phase 2 | Recruiting | Arialys Australia Pty Ltd | 30 | 2026-05-15 | 2026-10-27 |
| Clinical Features and Outcomes of VZV CNS Infections Varicella Zoster, Varicella Meningitis | Completed | Kocaeli University | 59 | 2026-04-17 | 2026-10-07 | |
| Prediction of Infectious Agents in the Biofire® FilmArray bioMérieux Meningitis/Encephalitis Panel Based on Clinical Syndrome and Cerebrospinal Fluid Parameters: a Diagnostic Stewardship Proposal. Biofire FilmArray Meningitis/Encephalitis Panel - Meningitis, Encephalitic Infection | Not applicable | Recruiting | Federal University of Health Science of Porto Alegre | 182 | 2026-04-13 | 2026-08-21 |
| T-cell Therapy in Patients With PML Application of T-lymphocytes - Progressive Multifocal Leucoencephalopathy (PML) | Phase 2 | Recruiting | Hannover Medical School | 23 | 2026-02-06 | 2026-10-15 |
| Clinicolaboratory Predictors of Outcome in Children With Encephalitis CSF analysis and culture including S100B,Neuron Specific Enolase(NSE) - Encephalitis in Children, Encephalitis | Not yet recruiting | Assiut University | 90 | 2026-01-01 | 2025-11-21 | |
| First-in-Human Study Testing a New Antibody Treatment for Tick-Borne Encephalitis in Healthy Volunteers. Human monoclonal antibody TBE025, intravenous infusion - The Tick-borne Encephalitis Virus (TBEV) | Phase 1 | Not yet recruiting | Giuseppe Pantaleo | 18 | 2026-01-01 | 2026-01-29 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies Optic Nerve Sheath Diameter - Meningitis, Meningitis/Encephalitis | Recruiting | Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș" | 200 | 2025-12-01 | 2026-01-12 | |
| KD Treatment for Super-refractory Status Epilepticus the ketogenic diet, Standard Medical Therapy - Super-refractory Status Epilepticus | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 84 | 2025-10-20 | 2026-05-15 |
| Diagnostics and Surveillance of Acute Meningo-encephalitis Among Children in Cambodia With a Focus on Japanese Encephalitis Virus Japanese Encephalitis | Not yet recruiting | ANRS, Emerging Infectious Diseases | 4000 | 2025-10-15 | 2025-09-11 | |
| Adjunctive Doxycycline for Central Nervous System Tuberculosis Doxycycline, Placebo, Anti Tuberculosis Drug - Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology) | Phase 2 | Recruiting | National University Hospital, Singapore | 200 | 2025-08-21 | 2026-06-01 |
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Encephalitis, Japanese (72) · Encephalitis, Tick-Borne (51) · Meningitis (33) · Leukoencephalopathy, Progressive Multifocal (29) · Autoimmune Diseases of the Nervous System (17) · Acquired Immunodeficiency Syndrome (15) · HIV Infections (14) · Anti-N-Methyl-D-Aspartate Receptor Encephalitis (13) · Virus Diseases (13) · Stroke (12) · West Nile Fever (12) · Brain Injuries, Traumatic (10) · Multiple Sclerosis (10) · Central Nervous System Infections (8)
Nervous System Diseases (315) · Neuroinflammatory Diseases (315) · Central Nervous System Diseases (313) · Brain Diseases (311) · Infections (245) · Central Nervous System Infections (224) · Central Nervous System Viral Diseases (212) · Virus Diseases (202) · Infectious Encephalitis (185) · Encephalitis, Viral (181) · RNA Virus Infections (175) · Vector Borne Diseases (149) · Arbovirus Infections (147) · Encephalitis, Arbovirus (147)
Japanese Encephalitis Vaccines (10) · Vaccines (10) · Blood Specimen Collection (6) · Pyrimethamine (6) · Doxycycline (4) · Hepatitis A Vaccines (4) · Immunoglobulins, Intravenous (4) · Leucovorin (4) · Desiccation (3) · FSME-IMMUN vaccine (3) · Saline Solution (3) · Sodium Chloride (3) · Surveys and Questionnaires (3) · Zidovudine (3) · Atovaquone (2)
Pfizer (20) · National Institute of Allergy and Infectious Diseases (NIAID) (17) · Valneva Austria GmbH (17) · Sanofi Pasteur, a Sanofi Company (13) · University Medical Centre Ljubljana (8) · PATH (7) · Sanofi (7) · National Institute of Neurological Disorders and Stroke (NINDS) (6) · U.S. Army Medical Research and Development Command (6) · Biogen (5) · Novartis (5) · University Hospital, Strasbourg, France (5) · Assistance Publique - Hôpitaux de Paris (4) · Hospices Civils de Lyon (4) · Assiut University (3)
United States (88) · Germany (29) · France (27) · China (21) · Austria (19) · United Kingdom (14) · Australia (10) · Sweden (10) · Poland (9) · Philippines (8) · Slovenia (8) · Thailand (8) · Italy (7) · Vietnam (7) · Canada (6)
Irene CM Cortese, M.D. (4) · Astrid Kaltenboeck, Ph.D. (3) · Luft B (3) · Ryszard Konior, MD (3) · Sarah Johnson (3) · Thiem D Vu, MD., PhD. (3) · Andrea Ayad, Dr. (2) · Anna Durbin, MD (2) · Anthony Cardile, DO (2)
PMID 20934459, PMID 21592984, PMID 28545923, PMID 11113214, PMID 12393404, PMID 15564716, PMID 15714427, PMID 15817019, PMID 17262855, PMID 17538176, PMID 18190252, PMID 18394765, PMID 18417336, PMID 18851928, PMID 19143532, PMID 19680671, PMID 20427647, PMID 20605905, PMID 20813797, PMID 20829370, PMID 20856164, PMID 20864814, PMID 21148499, PMID 21150279, PMID 21163445, PMID 21288804, PMID 21398392, PMID 21738597, PMID 21865579, PMID 22696017, PMID 22777096, PMID 23151040, PMID 23290630, PMID 23733308, PMID 23967083, PMID 24360484, PMID 24656175, PMID 24687904, PMID 24717964, PMID 24763533, PMID 24873986, PMID 24884681, PMID 25149833, PMID 25232151, PMID 25239483, PMID 25308927, PMID 25392198, PMID 25483480, PMID 25567119, PMID 25573986
2019 (2), 2005 (1), 2008 (1), 2009 (1), 2016 (1), 2023 (1), K01AG047279 (1), N01AI30025 (1), R01AG059008 (1), R21AG102953 (1), U01CK000176 (1)