2350 completed, 377 unknown, 209 recruiting, 162 terminated. 1041 Not applicable, 631 Phase 3, 449 Phase 2, 417 Phase 1, 357 Phase 4.
Follow Dyslipidemias: new trials by email Literature Review of Dyslipidemias trials Research Report on Dyslipidemias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient-engaged Development and Testing of Educational Content on Side Effects of Statins Educational content on statin side effects - Dyslipidemia | Not applicable | Suspended | Weill Medical College of Cornell University | 30 | 2028-09-01 | 2026-09-23 |
| Cardiometabolic Effects of the Recommended Daily Pecan Intake Dose Pecan, Control - Nutrition, Healthy, Dyslipidemia | Not applicable | Not yet recruiting | University of Georgia | 90 | 2027-03-01 | 2026-08-11 |
| Coronary Artery Calcium (CAC) Testing in Primary Care Our Practice Advisory (OPA) - ASCVD, ASCVD Management | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 20 | 2027-02-01 | 2026-10-15 |
| PCSK9 Inhibitors in Hyperlipidemia and Atherosclerosis Hyperlipidemia, Atherosclerotic Cardiovascular Disease (ASCVD) | Not yet recruiting | Fundación Santa Fe de Bogota | 100 | 2027-02-01 | 2026-10-02 | |
| A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical Atheroma Evolocumab, Routine Lipid Management, Autoinjector - Coronary Artery Disease, Hypercholesterolemia | Phase 4 | Not yet recruiting | Amgen | 308 | 2027-01-31 | 2026-09-21 |
| RCT for the Chinese Medicine in Treating Hypercholesterolemia Dachaihu Decoction combined Erzhiwan with variation, Placebo granules - Hypercholesterolemia | Phase 2 | Not yet recruiting | Chinese University of Hong Kong | 70 | 2027-01-01 | 2026-07-30 |
| An Observational Study to Evaluate Treatment Patterns in High, Very High and Extreme Cardiovascular Risk Patients With Hypercholesterolemia, Including Familial Hypercholesterolemia Hypercholesterolaemia, Familial Hypercholesterolaemia | Not yet recruiting | Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) | 2500 | 2027-01-01 | 2026-11-03 | |
| Germany on Target Registry No study-assigned intervention - Myocardial Infarction (MI), Dyslipidemias | Not yet recruiting | Deutsche Gesellschaft für Lipidologie e. V. (DGFL) - Lipid-Liga | 10000 | 2026-12-01 | 2026-09-28 | |
| Study of YKYY032 Injection in Adults With Hyperlipoproteinemia (a) YKYY032 group, YKYY032 Placebo group - Hyperlipoproteinemia (a) | Phase 2 | Not yet recruiting | Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd. | 192 | 2026-11-20 | 2026-11-03 |
| Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic Hyperlipidemia High fat liquid shake - Lipid Metabolism Disorders | Not applicable | Not yet recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 48 | 2026-11-08 | 2026-11-03 |
| Study of the Safety and Efficacy of Prenofitol Tablets 1 tablet of Prenofitol, 2 tablets of Prenofitol, 1 tablet of placebo - Dyslipidemia | Phase 2 | Not yet recruiting | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 160 | 2026-11-02 | 2026-11-02 |
| EDIT-401 in Adults Who Require Additional Lowering of Low-Density Lipoprotein Cholesterol (LDL-C) Drug: EDIT-401, Placebo - Heterozygous Familial Hypercholesterolemia (HeFH) | Phase 1 / Phase 2 | Not yet recruiting | Editas Medicine, Inc. | 56 | 2026-11-01 | 2026-10-26 |
| A Phase 1 Study of VELA-101 in Adult Participants VELA-101, Placebo - Healthy Participants, Hyperlipidemia | Phase 1 | Not yet recruiting | Ursa Medicines | 60 | 2026-11-01 | 2026-10-15 |
| Phase 2 Dose-Finding Study Evaluating the Efficacy and Safety of EDP167 in Adults With Mixed Dyslipidemia EDP167 100mg, EDP167 200mg, EDP167 300mg - Mixed Dyslipidemia | Phase 2 | Not yet recruiting | Eddingpharm (Zhuhai) Co., Ltd. | 144 | 2026-11-01 | 2026-09-02 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| Effectiveness and Tolerability of a Treat-to-Target Versus Fixed-Dose Statin Strategy in Patients With Atherosclerotic Cardiovascular Disease: A Randomized Controlled Trial Dose adjustment of statins, no dose adjustment - Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia, Stroke (CVA) or TIA | Phase 4 | Not yet recruiting | Rehman Medical Institute - RMI | 178 | 2026-11-01 | 2026-11-02 |
| Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care Alone for LDL-C Evaluation in Acute Coronary Syndrome Patients in Saudi Arabia inclisiran, SOC - Acute Coronary Syndrome | Phase 4 | Not yet recruiting | Novartis Pharmaceuticals | 300 | 2026-10-31 | 2026-10-30 |
| Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM) Team-based shared decision-making - Hypertension (HTN), Diabetes (DM) | Early Phase 1 | Not yet recruiting | Johns Hopkins University | 94 | 2026-10-30 | 2026-10-19 |
| Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic Risk Bupropion 150 mg, Lyophilized powder from edible mushrooms, Lifestyle Management - Cardiometabolic Syndrome, Obesity and Cardiovascular Risk | Phase 3 | Not yet recruiting | Uppsala University | 250 | 2026-10-30 | 2026-09-08 |
| Cascade Testing In Identifying At-risk Family Members Of Individuals With Familial Hypercholesterolemia (FH) In PCP Cascade testing, Standard of Care - Familial Hypercholesterolemia | Not applicable | Not yet recruiting | Mayo Clinic | 480 | 2026-10-20 | 2026-09-18 |
Showing 20 of 3402. Sign in to see all of them.
Hypercholesterolemia (1133) · Hyperlipidemias (846) · Hypertension (614) · Diabetes Mellitus (424) · Obesity (376) · Cardiovascular Diseases (353) · Hypertriglyceridemia (316) · Diabetes Mellitus, Type 2 (262) · Hyperlipoproteinemia Type II (226) · Metabolic Syndrome (208) · Atherosclerosis (173) · Insulin Resistance (145) · Overweight (133) · Coronary Artery Disease (103)
Nutritional and Metabolic Diseases (3394) · Lipid Metabolism Disorders (3342) · Metabolic Diseases (3342) · Hyperlipidemias (1491) · Vascular Diseases (948) · Glucose Metabolism Disorders (819) · Cardiovascular Diseases (785) · Pathological Conditions, Signs and Symptoms (680) · Endocrine System Diseases (666) · Signs and Symptoms (500) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (461) · Genetic Diseases, Inborn (438) · Nutrition Disorders (437) · Body Weight (430)
Atorvastatin (267) · Ezetimibe (205) · Rosuvastatin Calcium (191) · Simvastatin (132) · Fenofibrate (81) · evolocumab (65) · alirocumab (60) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (48) · Metformin (48) · Niacin (48) · Pravastatin (43) · Exercise (42) · pitavastatin (41) · Omacor (36) · 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid (33)
AstraZeneca (129) · Organon and Co (96) · Takeda (62) · Merck Sharp & Dohme LLC (58) · Chong Kun Dang Pharmaceutical (50) · National Heart, Lung, and Blood Institute (NHLBI) (48) · Novartis Pharmaceuticals (45) · Pfizer (45) · Amgen (44) · Sanofi (44) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (41) · Regeneron Pharmaceuticals (23) · University of Pennsylvania (22) · Yonsei University (20) · Eli Lilly and Company (19)
United States (1099) · Canada (343) · South Korea (283) · China (236) · Netherlands (178) · Germany (174) · Italy (162) · United Kingdom (160) · Spain (153) · France (152) · Australia (112) · Poland (103) · Denmark (99) · Czechia (98) · South Africa (95)
David JA Jenkins, MD, PhD, DSc (10) · Russell Esterline (10)
PMID 30183102, PMID 33078867, PMID 37994400, PMID 21518985, PMID 27777279, PMID 34298554, PMID 38018702, PMID 28181260, PMID 40587053, PMID 19793357, PMID 28304227, PMID 28324110, PMID 28964736, PMID 29685591, PMID 33990512, PMID 35277540, PMID 18783301, PMID 25614280, PMID 27578134, PMID 31194872, PMID 32609313, PMID 34677608, PMID 35916348, PMID 37565307, PMID 38063346, PMID 19744248, PMID 20136164, PMID 20573750, PMID 22301925, PMID 23661689, PMID 24239923, PMID 26872608, PMID 27206567, PMID 27659698, PMID 27888609, PMID 28391886, PMID 29037448, PMID 34617591, PMID 36520008, PMID 37658997, PMID 38504437, PMID 38757725, PMID 41604274, PMID 10205010, PMID 12485966, PMID 16034009, PMID 17126772, PMID 17384435, PMID 17407645, PMID 18996523
2005 (21), 2015 (18), 2023 (14), 2025 (10), 2016 (9), 2017 (9), 2018 (6), 2019 (6), 2014 (5), OT2HL158287 (5), 2008 (3), R01HL168858 (3), 2004 (2), 2009 (2), K23GM100372 (2)