24 completed, 6 unknown, 5 not yet recruiting, 5 recruiting. 33 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 33 | Completed 20, Recruiting 5, Unknown 4, Not yet recruiting 3, Terminated 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Head-Down Tilt: new trials by email Literature Review of Head-Down Tilt trials Research Report on Head-Down Tilt
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery Pneumoperitoneum and Trendelenburg Positioning - Acute Kidney Injury, Subclinical Acute Kidney Injury | Not yet recruiting | Medipol University | 50 | 2026-08-01 | 2026-07-15 | |
| Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain Pulmonary recruitment maneuver, Trendelenburg position - Pain, Post-operative, Pneumoperitoneum | Not applicable | Not yet recruiting | Ankita Gupta | 120 | 2026-06-01 | 2026-06-08 |
| Timing of Recruitment Maneuver in Robotic Prostate Surgery Recruitment maneuver after insufflation and Trendelenburg positioning, Recruitment maneuver in the supine position - Robotic Surgery, Urologic Surgical Procedures | Not applicable | Recruiting | Ankara University | 86 | 2026-05-09 | 2026-06-23 |
| Study on the Optimal Head Position for Patients With Severe Acute Ischemic Stroke head position - Stroke Acute | Not applicable | Not yet recruiting | West China Hospital | 1508 | 2026-05-01 | 2026-04-02 |
| Chinese Adaptive Randomised Pneumonia Trial With Respiratory Failure Trendelenburg Position, Traditional Chinese Medicine Formulation - Severe Pneumonia With Respiratory Failure | Phase 4 | Not yet recruiting | Peking Union Medical College Hospital | 1500 | 2026-02-20 | 2026-02-09 |
| Head dOwn Position Before Endovascular Treatment for Large veSsel Occlusion (HOPES5) head down position - Ischemic Stroke | Not applicable | Recruiting | General Hospital of Shenyang Military Region | 210 | 2025-09-02 | 2026-09-18 |
| Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients Trendelenburg position, Supine Horizontal Position - Hypotension on Induction, Old Age | Not applicable | Completed | Zhejiang Cancer Hospital | 168 | 2025-05-16 | 2026-04-09 |
| A Comparative Study of Ventilation Strategies in Different Surgical Positions on Intracranial Pressure and Cerebral Blood Flow During Laparoscopic Surgery Variable tidal volume ventilation (V-VCV), Pressure-regulated volume-controlled ventilation (PRVC), Conventional volume-controlled ventilation (C-VCV) - Laparoscopic Surgery | Not applicable | Not yet recruiting | Inner Mongolia Baogang Hospital | 240 | 2025-02-01 | 2025-02-03 |
| A Comparison Study Between 10 Days of Dry Immersion Versus 10 Days of Head-down Bedrest on 20 Healthy Male Volunteers 10 days of dry immersion, 10 days of Head Down Bed Rest - Weightlessness Simulation | Not applicable | Completed | Centre National d'Etudes Spatiales | 20 | 2024-12-09 | 2025-05-06 |
| Female Pelvic Blood Flow Under Simulated Microgravity Head down tilt (HDT) - Uterine, Ovary | Not applicable | Completed | Ceren UNAL | 20 | 2024-12-01 | 2025-11-28 |
| Head Down Position for Successful Recanalization of Anterior Circulation Large Vessel Occlusion (HOPES4) head down position - Ischemic Stroke | Not applicable | Completed | General Hospital of Shenyang Military Region | 90 | 2024-08-30 | 2025-11-20 |
| Effect of the Postoperative Trendelenburg Position on Chronic Subdural Hematoma Recurrence Trendelenburg position - Chronic Subdural Hematoma, Trendelenburg | Not applicable | Recruiting | Universidad de Antioquia | 254 | 2024-06-01 | 2025-04-22 |
| Trendelenburg Position for Acute Anterior Circulation Ischemic Stroke With Large Artery Atherosclerosis Etiology (HOPES 3) head-down position - Stroke, Acute Ischemic | Not applicable | Recruiting | General Hospital of Shenyang Military Region | 600 | 2024-01-10 | 2026-04-27 |
| Impact of Gravity on Cardiac Hemodynamics Cardiovascular and Baroreflex stimulation by Tilting, Cardiovascular and Baroreflex stimulation by Lower Body Negative Pressure - Diabetes type1, Healthy | Not applicable | Completed | University Hospital, Caen | 30 | 2023-11-22 | 2026-06-25 |
| Consol Time and Acute Kidney Injury in Robotic-assisted Prostatectomy Restrictive fluid therapy - Acute Kidney Injury, Hemodynamic Instability | Completed | Acibadem University | 42 | 2023-09-25 | 2024-02-02 | |
| Trendelenburg, Abdominal Insufflation and Time to Completion of Cystoscopy Flat position, Trendelenburg position, Insufflation - Bladder Integrity, Bladder Function | Not applicable | Completed | The University of Texas Health Science Center, Houston | 122 | 2023-04-11 | 2025-02-24 |
| The Effect of Patient Position Changes on Advanced Cardiac Indices in Cancer Surgery cardiac indices in supine and trendelenburg position - Abdominal Cancer, Blood Pressure | Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 80 | 2023-02-01 | 2026-04-30 | |
| Hemodynamic Effects of Trendelenburg Position and Pneumoperitoneum in Urologic Robotic Surgery Pneumoperitoneum and Trendelenburg Position - Pneumoperitoneum, Artificial, Hemodynamics | Completed | Ege University | 55 | 2022-11-29 | 2026-09-30 | |
| Head Position on Pediatric Nasotracheal Intubation Head position - Intubation | Not applicable | Completed | Ajou University School of Medicine | 108 | 2022-05-18 | 2024-07-25 |
| Shoulder Pain and Post Gynecologic Laparoscopic Recovery Trendelenburg Position, Warm Pad Application, Deep Breathing Exercise - Gynecologic Nursing, Postoperative Pain | Not applicable | Completed | Alexandria University | 90 | 2022-05-01 | 2023-02-02 |
Showing 20 of 41. Sign in to see all of them.
Ischemic Stroke (4) · Pneumoperitoneum (4) · Acute Kidney Injury (2) · Hypotension (2) · Hypovolemia (2) · Pain, Postoperative (2) · Shock (2) · Stroke (2) · Diabetes Mellitus (1) · Gastrointestinal Neoplasms (1) · Hematoma, Subdural, Chronic (1) · Hypotension, Orthostatic (1) · Hypoxia (1) · Intracranial Hypotension (1) · Ischemia (1)
General Hospital of Shenyang Military Region (3) · Ajou University School of Medicine (2) · Acibadem University (1) · Alexandria University (1) · Ankara City Hospital Bilkent (1) · Ankara University (1) · Ankita Gupta (1) · Assistance Publique - Hôpitaux de Paris (1) · Cairo University (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Centre National d'Etudes Spatiales (1) · Ceren UNAL (1) · Clinica Alemana de Santiago (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital (1)
China (7) · Turkey (Türkiye) (7) · France (6) · South Korea (4) · United States (3) · Egypt (2) · Poland (2) · Australia (1) · Chile (1) · Colombia (1) · Israel (1) · Russia (1) · Saudi Arabia (1)
Abdo M Saad, MD (1) · Afak Durur Karakaya, M.D. (1) · Chung Su Kim, M.D.,Ph.D. (1) · Eman Taha (1) · Fevzi Toraman, M.D. (1) · Isilay Ayar Gecginer, MD (1) · Italo Biaggioni, MD (1) · J. A Taylor, PhD (1) · Jan Stefaniak, M.D. (1)
PMID 29208025, PMID 21815239, PMID 23549128, PMID 24128839, PMID 24358000, PMID 25233178, PMID 26783317, PMID 26817405, PMID 27742914, PMID 28168868, PMID 28581366, PMID 33020097, PMID 33819496, PMID 36383279, PMID 38133925, PMID 38296589, PMID 40770328, PMID 41778610
R21AR074054 (1)