12 completed, 8 unknown, 6 recruiting, 2 not yet recruiting. 7 Not applicable, 5 Phase 4, 4 Phase 3, 3 Phase 2, 1 Phase 1.
Follow Fibrinolytic Agents: new trials by email Literature Review of Fibrinolytic Agents trials Research Report on Fibrinolytic Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 Tenecteplase or Alteplase- depending upon availability at each treating centre, Control - Stroke, Acute Ischemic, Endovascular Thrombectomy | Phase 3 | Recruiting | University of Calgary | 1500 | 2026-08-11 | 2026-10-21 |
| STRATEGY-PE: Real-World Treatment Strategies for Intermediate-High Risk Pulmonary Embolism Anticoagulants, Thrombolytic Agents, Mechanical Thrombectomy Devices - Pulmonary Embolism, Venous Thromboembolism | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1300 | 2026-06-01 | 2026-05-22 | |
| Second Line Endovascular Treatment in Acute DVT Thrombolysis/Thrombectomy - Deep Venous Thrombosis | Phase 4 | Not yet recruiting | Rush University Medical Center | 100 | 2026-04-01 | 2026-01-28 |
| TrIal of Early Minimally Invasive Catheter Evacuation With Thrombolysis in IntraCerebral Hemorrhage Early Minimally Invasive Surgery with Thrombolysis (eMIST) - Intracerebral Hemorrhage | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 750 | 2025-10-24 | 2026-10-20 |
| 'Thrombectomy in High-Risk Pulmonary Embolism - Device Versus Thrombolysis Netherlands': TORPEDO-NL Catheter-directed thrombectomy (CDT), thrombolysis therapy - Pulmonary Embolism Acute | Not applicable | Recruiting | Leiden University Medical Center | 111 | 2025-02-01 | 2025-02-19 |
| Efficacy and Safety Study of Ultra-early Mobile Stroke Unit Neuroprotection Combined With Revascularization for Acute Ischemic Stroke (EXCELLENT) Intravenous thrombolysis + edaravone, IV thrombolysis + placebo (control group) - Ischemic Stroke | Phase 4 | Recruiting | Ruijun Ji | 300 | 2024-08-01 | 2025-08-12 |
| Evaluation of the Standard Catheter-directed Thrombolysis Effectiveness in Intermediate-High-Risk Pulmonary Embolism Patients Standard Catheter-Directed Low Dose Thrombolysis, Standard Anticoagulation - Pulmonary Embolism Acute | Not applicable | Recruiting | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | 100 | 2024-01-10 | 2024-07-05 |
| Intravenous Tirofiban Versus Thrombolysis Before Mechanical Thrombectomy in Stroke Tirofiban, Thrombolysis - Stroke, Acute Ischemic | Phase 2 / Phase 3 | Completed | Xinqiao Hospital of Chongqing | 1014 | 2023-11-28 | 2026-09-14 |
| Catheter-directed Thrombolysis in Intermediate-high Risk Acute Pulmonary Embolism Thrombolytic, Standard anticoagulation - Pulmonary Embolism | Phase 4 | Completed | Faculty Hospital Kralovske Vinohrady | 558 | 2022-10-19 | 2026-06-18 |
| Thrombolysis in STEMI Patients Compared With pPCI on Recanalization Time in the Context of the COVID-19 Outbreak. Thrombolytic, percutaneous coronary stenting - STEMI - ST Elevation Myocardial Infarction | Not applicable | Unknown | Ya-Wei Xu | 120 | 2022-04-01 | 2022-05-26 |
| Platelet Function in Patients With Ischemic Stroke Treated With Anti-thrombotic or Thrombolytic Thrombolytic Agent - Acute Ischemic Stroke | Phase 1 / Phase 2 | Unknown | Baylor College of Medicine | 30 | 2022-02-18 | 2022-06-10 |
| The Prevalence and Associated Factors of Early Deterioration After Successful Recanalization in Acute Ischemic Stroke Alteplase Injection - Acute Stroke | Unknown | Assiut University | 30 | 2021-08-01 | 2021-07-27 | |
| Acute STROke Complicating TAVI - Management and Outcomes Mechanical thrombectomy, Thrombolytic Agent - Stroke, Aortic Valve Stenosis | Completed | Rabin Medical Center | 484 | 2021-06-01 | 2022-02-16 | |
| The Relationship Between MPV,PDW,PFT and ST Segment Resolution in STEMI Patients Treated With Thrombolytic or Primary PCI Thrombolytic, Primary PCI, Complete blood count - STEMI - ST Elevation Myocardial Infarction | Withdrawn | Assiut University | 2020-12-01 | 2023-02-03 | ||
| Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI) Antithrombotic Agent - Atrial Fibrillation, Myocardial Infarction | Unknown | Scientific Institute San Raffaele | 1500 | 2020-01-25 | 2020-03-26 | |
| Acute Myocardial Infarction Study in Northeastern China thrombolysis - Acute Myocardial Infarction | Unknown | Second Hospital of Jilin University | 3159 | 2019-09-09 | 2020-06-30 | |
| Ongoing Registry of Treatment of Venous Thromboembolism Anticoagulants, Open surgery, Thrombolysis - Deep Vein Thrombosis, Thromboses, Venous | Recruiting | Medalp Private Surgery Clinic | 5000 | 2019-04-01 | 2025-05-08 | |
| Sterotactic Operation Integrating With Thrombolysis in Basal Ganglion Hemorrhage Evacuation stereotactic surgery plus thrombolysis, Guideline-based standard medical management - Basal Ganglia Haematoma | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 380 | 2019-01-01 | 2026-09-23 |
| Catheter Directed Interventions in Pulmonary Embolism catheter directed fragmentation and thrombolysis, Streptokinase - Pulmonary Embolism | Not applicable | Unknown | Assiut University | 60 | 2018-09-01 | 2018-07-24 |
| Study of Antithrombotic Treatment After IntraCerebral Haemorrhage Antithrombotic Agent - Cerebral Hemorrhage, Intracranial Hemorrhages | Phase 4 | Terminated | Oslo University Hospital | 134 | 2018-07-01 | 2025-02-12 |
Showing 20 of 31. Sign in to see all of them.
Ischemic Stroke (8) · Stroke (6) · Pulmonary Embolism (5) · Atrial Fibrillation (3) · ST Elevation Myocardial Infarction (3) · Acute Coronary Syndrome (2) · Brain Diseases (2) · Cerebral Hemorrhage (2) · Cerebrovascular Disorders (2) · Intracranial Hemorrhages (2) · Venous Thrombosis (2) · Aortic Valve Stenosis (1) · Basal Ganglia Hemorrhage (1) · Brain Ischemia (1) · Cardiovascular Diseases (1)
Assiut University (3) · Second Hospital of Jilin University (2) · University of Calgary (2) · Aarhus University Hospital (1) · Bayer (1) · Baylor College of Medicine (1) · Beijing Chao Yang Hospital (1) · Charite University, Berlin, Germany (1) · Chinese University of Hong Kong (1) · Faculty Hospital Kralovske Vinohrady (1) · Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Johns Hopkins University (1) · Leiden University Medical Center (1) · Medalp Private Surgery Clinic (1)
China (11) · Canada (3) · Germany (3) · United States (3) · Denmark (2) · Russia (2) · Sweden (2) · Australia (1) · Czechia (1) · Israel (1) · Italy (1) · Netherlands (1) · Norway (1) · Spain (1) · United Kingdom (1)
Andrew M Demchuk, MD FRCPC (1) · Bijoy K Menon, MD (1) · Bin Liu, Doctor (1) · Bin Liu, Ph.D (1) · Bulent Arslan, MD (1) · Congguo Yin, Doctor (1) · Craig Anderson, MD (1) · Daniel F Hanley, MD (1) · F. A. Klok, Prof. MD. PhD. (1) · Grethe Andersen, M.D Doctor (1) · Heinrich J Audebert, MD (1) · Jingwen Wang (1)
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