206 completed, 46 recruiting, 45 unknown, 21 not yet recruiting. 271 Not applicable, 13 Phase 2, 8 Phase 4, 6 Phase 3, 5 Early Phase 1.
Follow Sleep Disturbance: new trials by email Literature Review of Sleep Disturbance trials Research Report on Sleep Disturbance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation - Sleep Disturbance, Sleep Problems | Not applicable | Not yet recruiting | Universidad Pública de Navarra | 250 | 2026-10-09 | 2026-10-08 |
| eMindExCare for Prostate Cancer Patients Undergoing Active Treatment eMindExCare, Enhanced Health Education - Prostate Cancer, Sleep Disturbance | Not applicable | Not yet recruiting | The University of Hong Kong | 60 | 2026-10-01 | 2026-07-29 |
| Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy - Spinal Cord Injuries (SCI), Chronic Pain | Not applicable | Not yet recruiting | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 40 | 2026-10-01 | 2026-09-29 |
| Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Bao Yuan Tang full-component extract 2.0g plus a placebo consisting of maltodextrin 2.0g, Galactooligosaccharides 2.0g - Sleep Disturbance, Fatigue Syndrome, Chronic | Not applicable | Not yet recruiting | Hepatopancreatobiliary Surgery Institute of Gansu Province | 400 | 2026-09-30 | 2026-08-19 |
| Pilot Trial for Health Products on Mood and Sleep Quality Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF), Placebo - Sleep Disturbance, Emotional Disturbance | Not applicable | Recruiting | The University of Hong Kong | 60 | 2026-09-22 | 2026-10-02 |
| Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4 Sleep Disturbance, Cognitive Change | Recruiting | Chang Gung Memorial Hospital | 250 | 2026-09-15 | 2026-07-30 | |
| Effect of a Nurse-Led Environmental Stressor Reduction Package on Perceived Stress and Sleep Quality in Intensive Care Unit Patients Environmental Stressor Reduction Package - Sleep Disturbance | Not applicable | Not yet recruiting | Fenerbahce University | 68 | 2026-09-01 | 2026-08-18 |
| Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients Lemborexant, Placebo - Sleep Disturbance, Delirium | Phase 4 | Recruiting | Mahidol University | 100 | 2026-09-01 | 2026-10-08 |
| Daridorexant for Sleep Disturbance in Adults With Liver Cirrhosis Daridorexant, Placebo - Liver Cirrhosis, Sleep Disturbance | Phase 4 | Not yet recruiting | Wang Fengmei | 180 | 2026-09-01 | 2026-10-16 |
| GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults Active Gut Feeling Product 1, Active Gut Feeling Product 2, Placebo Gut Feeling Control Product - Sleep Disturbance, Stress | Not applicable | Recruiting | Holobiome, Inc. | 1000 | 2026-08-31 | 2026-10-19 |
| Radicle RestTM VGI: A Study Assessing the Impact of Health and Wellness Products on Sleep and Related Health Outcomes Placebo Rest Control, Active Rest Product 1 - Sleep Disturbance | Not applicable | Active not recruiting | Radicle Science | 600 | 2026-08-11 | 2026-09-02 |
| Tension-type Headache and Its Association Tension-Type Headache, Sleep Disturbance | Not yet recruiting | Assiut University | 199 | 2026-08-10 | 2026-08-24 | |
| Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder TMS - Insomnia, Chronic Insomnia | Not applicable | Enrolling by invitation | San Francisco Neurology and Sleep Center | 70 | 2026-08-05 | 2026-08-13 |
| Comparison Between the Effect of Two Different Doses of Oral Melatonin on Sleep Quality After Total Hip Arthroplasty Melatonin 5 MG, Melatonin 10 MG, Placebo - Sleep Disturbance | Early Phase 1 | Not yet recruiting | Benha University | 150 | 2026-08-04 | 2026-07-29 |
| Sleep Interventions and Neurocognitive Outcomes Acoustic slow-wave activity enhancement, Cognitive behavioral therapy for insomnia - Sleep Disturbance, Amnestic Mild Cognitive Impairment | Not applicable | Not yet recruiting | New York State Psychiatric Institute | 50 | 2026-08-01 | 2026-08-03 |
| Effects of Exercise Intervention on Sleep Quality and Emotional Problems in College Students With Depressive Symptoms Archery Exercise, Non-exercise Control - Depressive Symptoms, Sleep Disturbance | Not applicable | Not yet recruiting | Capital University of Physical Education and Sports, China | 80 | 2026-08-01 | 2026-07-31 |
| Telephone-Coached Sleep Bibliotherapy for Dementia Caregivers Telephone-Coached Sleep Bibliotherapy, Educational Booklet - Sleep Disturbance, Dementia | Not applicable | Recruiting | The Hong Kong Polytechnic University | 120 | 2026-08-01 | 2026-09-17 |
| Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation - Anxiety, PTSD | Not applicable | Active not recruiting | Tactical Mind Research Coalition, Inc. | 240 | 2026-08-01 | 2026-09-16 |
| Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses Non-Invasive Sleep Monitoring - Burnout, Sleep Disturbance | Not yet recruiting | Kaohsiung Armed Forces General Hospital | 100 | 2026-08-01 | 2026-06-24 | |
| NeuroFinance Human Stress Trial During Financial and Informational Volatility Wearable Physiologic Monitoring Platform - Psychological Stress, Anxiety | Enrolling by invitation | Truway Health, Inc. | 2500 | 2026-07-15 | 2026-08-25 |
Showing 20 of 355. Sign in to see all of them.
Parasomnias (355) · Sleep Initiation and Maintenance Disorders (74) · Anxiety Disorders (51) · Depression (40) · Sleep Wake Disorders (34) · Fatigue (31) · Pain (19) · Sleep Hygiene (12) · Stress Disorders, Post-Traumatic (12) · Sleep Deprivation (11) · Cognitive Dysfunction (10) · Alzheimer Disease (9) · Attention Deficit Disorder with Hyperactivity (9) · Chronic Pain (9) · Dementia (9)
Nervous System Diseases (354) · Mental Disorders (352) · Sleep Wake Disorders (321) · Pathological Conditions, Signs and Symptoms (136) · Signs and Symptoms (118) · Dyssomnias (97) · Neurologic Manifestations (89) · Sleep Disorders, Intrinsic (86) · Behavior (81) · Behavioral Symptoms (56) · Pathologic Processes (33) · Central Nervous System Diseases (30) · Brain Diseases (27) · Neurocognitive Disorders (26) · Respiratory Tract Diseases (22)
Cognitive Behavioral Therapy (14) · Melatonin (10) · Saline Solution (5) · Surveys and Questionnaires (5) · Esketamine (4) · Sleep (4) · Cannabidiol (3) · Polysomnography (3) · Sodium Chloride (3) · Yoga (3) · suvorexant (3) · Acupuncture, Ear (2) · Anesthesia, Conduction (2) · Anesthesia, General (2) · Art Therapy (2)
University of Pittsburgh (10) · Johns Hopkins University (9) · Radicle Science (7) · Assiut University (5) · Chinese University of Hong Kong (5) · Stanford University (5) · University of Utah (5) · Arizona State University (4) · Chang Gung Memorial Hospital (4) · Children's Hospital of Philadelphia (4) · Indiana University (4) · University of Arizona (4) · University of Calgary (4) · University of California, San Francisco (4) · Ataturk University (3)
United States (173) · Turkey (Türkiye) (23) · Canada (15) · China (14) · United Kingdom (14) · Hong Kong (12) · Taiwan (10) · Denmark (7) · Sweden (7) · Egypt (5) · Norway (5) · Germany (4) · Switzerland (4) · Italy (3) · Mexico (3)
Emily K. Pauli, PharmD (3) · Jennifer Huberty, PhD (3) · Michael G Smith, PhD (3) · Amy G Hartman, PhD (2) · Anar Murphy, PhD (2) · Andrea Goldstein-Piekarski, PhD (2) · Andrew S Huhn, PhD (2) · Ariel Williamson, PhD (2) · Birna Baldursdottir, PhD (2) · Christina Barkauskas, MD (2) · Christopher M Cielo, DO (2) · Guolin Wang (2) · Jessica C Levenson (2)
PMID 2748771, PMID 11556271, PMID 16717171, PMID 24634631, PMID 39198005, PMID 39436396, PMID 10668003, PMID 11704164, PMID 12964174, PMID 14998254, PMID 16814632, PMID 17197840, PMID 17505231, PMID 1779413, PMID 17999228, PMID 18388841, PMID 18715244, PMID 19689221, PMID 19725252, PMID 20089179, PMID 20133153, PMID 20137989, PMID 20171069, PMID 20626359, PMID 21237680, PMID 21243655, PMID 21750313, PMID 22120045, PMID 22120461, PMID 22123869, PMID 22207903, PMID 22277666, PMID 22294820, PMID 22771125, PMID 22831887, PMID 22987089, PMID 23185361, PMID 23356673, PMID 23469262, PMID 23583623, PMID 23663938, PMID 23711168, PMID 23971909, PMID 23993773, PMID 24179309, PMID 24300462, PMID 24497658, PMID 24643100, PMID 24793909, PMID 25142566
2025 (2), P30AG064198 (2), R34MH132724 (2), 2017 (1), 2019 (1), 3UG1CA189824-04S1 (1), I01CX002591 (1), K01HL149987 (1), K01NR017465 (1), K08CA247973 (1), K23AG070378 (1), K23AG078448 (1), K23HD087433 (1), K23HD094905 (1), K99NR021195 (1)