5 completed, 5 terminated, 5 unknown. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 5, Terminated 5, Unknown 5 |
Follow Sleep Disorder: new trials by email Literature Review of Sleep Disorder trials Research Report on Sleep Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| the Effects of Different Therapy Regimens on Menopausal Sleep Disorders Tibolone, Xiangshao granules, Tibolone plus Xiangshao granules - Menopause, Sleep Disorder | Phase 4 | Unknown | Peking Union Medical College Hospital | 180 | 2023-12-30 | 2024-01-02 |
| Effects of Melissa Extract on Sleep Characteristics Melissa phytosome, Placebo - Sleep Disorder, Anxiety | Phase 4 | Unknown | University of Urbino "Carlo Bo" | 40 | 2023-09-01 | 2023-07-18 |
| Effect of Propofol on Postoperative Sleep Quality in Elderly Patients With Sleep Disorders Propofol, Dexmedetomidine, Saline - Sleep Disorder | Phase 4 | Unknown | Xiangya Hospital of Central South University | 321 | 2022-12-01 | 2022-10-03 |
| Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia Suvorexant, Placebo - Restless Legs Syndrome, Insomnia | Phase 4 | Completed | Massachusetts General Hospital | 46 | 2021-08-12 | 2024-01-16 |
| Fremanezumab, Migraine and Sleep Fremanezumab Prefilled Syringe [Ajovy] - Migraine Disorders, Sleep Disorder | Phase 4 | Terminated | Beth Israel Deaconess Medical Center | 22 | 2021-07-29 | 2026-02-27 |
| Yangzheng Compound Mixture in the Treatment of Sleep Disorder in Cancer Patients Yangzheng Compound Mixture, Conventional Treatment - Carcinoma, Sleep Disorder | Phase 4 | Unknown | ShuGuang Hospital | 1127 | 2021-04-27 | 2024-05-31 |
| Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder Ferrous sulfate - Sleep Disorder, Restless Legs Syndrome | Phase 4 | Terminated | Mayo Clinic | 6 | 2020-11-16 | 2024-05-22 |
| Melatonin in ADHD and Sleep Problems Melatonin 3 mg - Attention Deficit Hyperactivity Disorder, Sleep Disorder | Phase 4 | Unknown | Allan Hvolby | 80 | 2020-09-01 | 2022-05-09 |
| Opioid-Free Anesthetic for Tonsillectomy Ketorolac, Dexmedetomidine, Morphine - Anesthesia, Opioid Use | Phase 4 | Terminated | Children's Hospital of Philadelphia | 35 | 2020-07-22 | 2024-12-20 |
| Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes Suvorexant, Placebo - Type 2 Diabetes Mellitus, Insomnia | Phase 4 | Completed | Massachusetts General Hospital | 108 | 2019-03-15 | 2024-08-20 |
| Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient polysomnography, Trazodone, Placebos - TMD, Sleep Bruxism | Phase 4 | Terminated | Centre hospitalier de l'Université de Montréal (CHUM) | 3 | 2018-10-15 | 2020-02-05 |
| Substudy on the Mechanistic Plausibility of the Clinical Benefits of Adaptive Servo-ventilation adaptive servoventilation (ASV) - Heart Failure, Sleep Disorder | Phase 4 | Completed | ResMed | 312 | 2012-08-01 | 2015-08-07 |
| Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum Disorders Natrol - Sleep Disorder | Phase 4 | Terminated | University of Nebraska | 1 | 2010-03-04 | 2023-09-08 |
| Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome Eszopiclone, Placebo - Acute Coronary Syndrome, Sleep Disorder | Phase 4 | Completed | University of Arizona | 5 | 2007-10-01 | 2016-12-20 |
| The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726) Mometasone furoate nasal spray, Placebo - Perennial Allergic Rhinitis, Obstructive Sleep Apnea | Phase 4 | Completed | Organon and Co | 30 | 2006-05-01 | 2024-05-23 |
Sleep Wake Disorders (15) · Sleep Initiation and Maintenance Disorders (3) · Restless Legs Syndrome (2) · Acute Coronary Syndrome (1) · Anemia, Iron-Deficiency (1) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Autism Spectrum Disorder (1) · Carcinoma (1) · Cheyne-Stokes Respiration (1) · Chronic Pain (1) · Diabetes Mellitus, Type 2 (1) · Heart Failure (1) · Inflammation (1) · Migraine Disorders (1)
Mental Disorders (15) · Nervous System Diseases (15) · Neurologic Manifestations (15) · Pathological Conditions, Signs and Symptoms (15) · Signs and Symptoms (15) · Dyssomnias (6) · Sleep Disorders, Intrinsic (6) · Parasomnias (3) · Respiratory Tract Diseases (3) · Apnea (2) · Cardiovascular Diseases (2) · Heart Diseases (2) · Metabolic Diseases (2) · Neurodevelopmental Disorders (2) · Nutritional and Metabolic Diseases (2)
Dexmedetomidine (2) · suvorexant (2) · Eszopiclone (1) · Fentanyl (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Melatonin (1) · Mometasone Furoate (1) · Morphine (1) · Polysomnography (1) · Propofol (1) · Sodium Chloride (1) · Trazodone (1) · erenumab (1) · ferrous sulfate (1)
Massachusetts General Hospital (2) · Allan Hvolby (1) · Beth Israel Deaconess Medical Center (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Children's Hospital of Philadelphia (1) · Mayo Clinic (1) · Organon and Co (1) · Peking Union Medical College Hospital (1) · ResMed (1) · ShuGuang Hospital (1) · University of Arizona (1) · University of Nebraska (1) · University of Urbino "Carlo Bo" (1) · Xiangya Hospital of Central South University (1)
United States (7) · China (2) · Australia (1) · Canada (1) · Czechia (1) · Denmark (1) · Finland (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Allan Hvolby, MD, Ph.D (1) · Anthony Sheyn, MD, FACS (1) · Gilles Lavigne (1) · Holger Woehrle, MD (1) · Howard Needelman, MD (1) · John W Winkelman, MD, PhD (1) · John W Winkelman, MD/PhD (1) · Julie Baughn, MD (1) · Martin Cowie, Prof (1) · Qi Li, PhD (1) · Rong Chen, Professor (1) · Sairam Parthasarathy, MD (1) · Sait Ashina, MD (1) · Tori Sutherland, MD,MPH (1)