100 completed, 15 unknown, 12 recruiting, 9 terminated. 58 Not applicable, 34 Phase 3, 32 Phase 4, 22 Phase 2, 4 Early Phase 1.
Follow ferrous sulfate: new trials by email Literature Review of ferrous sulfate trials Research Report on ferrous sulfate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia Ferrous sulfate 325mg - Right Ventricular Dysfunction, Hypoxia | Early Phase 1 | Not yet recruiting | University of Colorado, Denver | 5 | 2028-03-01 | 2026-04-29 |
| A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep Ferrous Sulfate, Placebo - ADHD, Sleep Problems | Phase 1 / Phase 2 | Not yet recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 70 | 2027-03-01 | 2026-05-04 |
| COMPARISON OF EFFICACY OF ORAL VS IV IRON THERAPY IN CHILDREN AGED 12-59 MONTHS, WITH IRON DEFICIENCY ANEMIA Oral ferrous sulfate, iron sucrose - Iron Deficiency Anemia in Children | Phase 2 | Not yet recruiting | Kharadar General Hospital | 100 | 2027-01-01 | 2026-06-18 |
| IRONCARE: Iron Treatment in Older Patients With Hip Fractures Ferric Derisomaltose, Oral Iron (Ferrous sulphate), Placebo IV - Hip Fracture, Anemia | Phase 4 | Not yet recruiting | University of Aarhus | 528 | 2026-10-01 | 2026-06-24 |
| Daily Versus Alternate-Day Oral Iron Therapy for Anemia in Second-Trimester Pregnancy Ferrous Sulfate - Iron Deficiency Anemia, Anemia in Pregnancy | Not applicable | Not yet recruiting | Pakistan Air Force (PAF) Hospital Islamabad | 184 | 2026-09-01 | 2026-06-18 |
| Exploring the Efficacy of Ferrous Sulfate/Ferrous Succinate Combined With Serplulimab and SOX Regimen in Neoadjuvant Therapy for Gastric Cancer: A Prospective Cohort Study Ferrous succinate, Ferrous Sulfate, Serplulimab - Gastric Neoplasms | Phase 2 | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 54 | 2026-09-01 | 2026-10-14 |
| Improving Iron Levels in Female Endurance, Intermittent, and Power/Strength Athletes Aged 16-35 Low-dose iron (ferrous sulfate), Yeast-bound iron (ferrous sulfate), High-dose iron (ferrous sulfate) - Iron Deficiency | Not applicable | Recruiting | University of Calgary | 36 | 2026-03-26 | 2026-04-17 |
| The Role of Ferric Carboxymaltose in the Treatment of Pediatric Iron Deficiency Anemia in the Emergency Department Ferric Carboxymaltose (FCM), Ferrous Sulfate - Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease, Iron Deficiency Anaemia Due to Dietary Causes | Phase 4 | Not yet recruiting | Children's Hospital of Orange County | 150 | 2026-01-31 | 2026-02-17 |
| Acupoint TENS vs Resistance Training for Iron Deficiency Anemia Acupuncture transcutaneous electrical nerve stimulation (Acu-TENS), Resistance exercise training, Ferrous Sulfate - Iron Deficiency Anemia | Phase 4 | Recruiting | Cairo University | 60 | 2026-01-15 | 2026-05-26 |
| Comparing High and Low Dose Iron Treatments for People on Peritoneal Dialysis: The PALaDIN Study Monofer (iron isomaltoside 1000), Ferrous Sulfate - Peritoneal Dialysis, Anaemia | Phase 3 | Recruiting | Hull University Teaching Hospitals NHS Trust | 30 | 2025-11-13 | 2026-05-06 |
| Oral Iron for the Management of Iron Deficiency Anemia in SGLT2i-Treated Heart Failure Patients Oral iron supplementation - Heart Failure, Anemia | Phase 3 | Completed | Universidade do Porto | 55 | 2025-09-20 | 2026-07-16 |
| Risk of Anemia and Effects of Oral Iron Therapy in Non-Anemic Iron-Deficient Women (18-55 Years) Dietary Intervention (2 months), Oral Elemental Iron (Ferrous Sulfate) 80 mg/day - Non-Anemic Iron Deficiency | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 60 | 2025-09-01 | 2025-12-04 |
| Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity Ferrous sulfate - Obesity, Iron Deficiency | Not applicable | Recruiting | Linda Malan | 70 | 2025-07-24 | 2026-03-23 |
| IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches Ferric Carboxymaltose, Ferrous Sulfate - Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF) | Phase 4 | Terminated | Syed Hamza Mufarrih | 42 | 2025-04-02 | 2026-07-20 |
| Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women ferrous sulfate 80 mg, ferrous sulfate 160 mg - Iron Deficiency Without Anemia | Not applicable | Recruiting | Swiss Federal Institute of Technology | 120 | 2025-02-25 | 2025-05-20 |
| Comparison of Oral vs Intravenous Iron Therapy for the Treatment of Postpartum Anemia Ferric Carboxy Maltose, Ferrous Sulfate - Postpartum Anaemia | Not applicable | Completed | Shahida Islam Medical Complex | 122 | 2025-02-18 | 2026-01-14 |
| Effectiveness of Oral Iron Therapy in Iron Deficiency Anemia With Daily vs Alternate Day Dosing Ferrous sulphate - Iron Deficiency Anemia, Iron Deficiency Anemia Treatment | Phase 3 | Completed | University of Child Health Sciences and Children's Hospital, Lahore | 60 | 2025-01-07 | 2026-06-16 |
| Different Oral Iron Dosing Regimens in Treatment of Iron Deficency Anemia in Patients With Chronic Kidney Disease Ferrous sulfate - CKD | Unknown | Assiut University | 150 | 2024-08-01 | 2024-07-25 | |
| Measuring Iron Bioavailability From Oral Iron Supplements in Healthy Pre-menopausal Women Using Stable Isotopes 5mg Spatone, 10mg Spatone, 15mg Spatone - Iron Deficiency Anaemia Due to Dietary Causes | Not applicable | Completed | King's College London | 14 | 2024-01-13 | 2026-05-04 |
| Kids With Iron Deficiency and Scoliosis Oral ferrous sulfate, Oral placebo tablet - Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis | Not applicable | Recruiting | Columbia University | 275 | 2024-01-11 | 2026-06-26 |
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Anemia, Iron-Deficiency (67) · Anemia (53) · Iron Deficiencies (45) · Renal Insufficiency, Chronic (7) · Heart Failure (4) · Inflammation (4) · Restless Legs Syndrome (4) · Fatigue (3) · Malaria (3) · Menorrhagia (3) · Attention Deficit Disorder with Hyperactivity (2) · Hip Fractures (2) · Iron Overload (2) · Iron-Refractory Iron Deficiency Anemia (2) · Motor Activity (2)
Swiss Federal Institute of Technology (8) · American Regent, Inc. (5) · Iowa State University (5) · Baylor College of Medicine (3) · Cornell University (3) · Indiana University (3) · Medical Research Council (3) · Assiut University (2) · Cairo University (2) · Columbia University (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (2) · Imperial College London (2) · London School of Hygiene and Tropical Medicine (2) · Mayo Clinic (2)
United States (57) · United Kingdom (14) · Switzerland (11) · Egypt (7) · Pakistan (7) · Brazil (4) · Canada (4) · China (4) · Germany (4) · Turkey (Türkiye) (4) · Australia (3) · Denmark (3) · Sweden (3) · The Gambia (3) · France (2)
Manju B Reddy, PhD (3) · Alison E Pritchard, PhD (2) · Jonathan Powell, PhD (2) · Manju B Reddy, Ph.D. (2) · Raymond D Pratt, MD, FACP (2) · Adetokunbo O Tayo, M.D. (1) · Ahmed Gaber Ahmed (1) · Ahmed Mamdouh (1) · Aijun AJ Sun, MD (1) · Alex H Gifford, M.D. (1) · Alexander Krafft, Dr. (1) · Ammara Suleman, MBBS (1)
PMID 26289639, PMID 34839481, PMID 10341379, PMID 11918106, PMID 14733976, PMID 15824508, PMID 16316362, PMID 17109795, PMID 17296819, PMID 17352947, PMID 17520797, PMID 17666600, PMID 17671050, PMID 18555170, PMID 18670706, PMID 19149890, PMID 19186083, PMID 19245362, PMID 19398354, PMID 19458014, PMID 19491110, PMID 19780472, PMID 19920054, PMID 20620105, PMID 21336156, PMID 21336159, PMID 21643649, PMID 22089308, PMID 22272750, PMID 22296075, PMID 22382172, PMID 22786531, PMID 23680589, PMID 23835333, PMID 24115337, PMID 24195864, PMID 24332997, PMID 24590680, PMID 24756645, PMID 24891437, PMID 24899360, PMID 25057155, PMID 25639592, PMID 25700159, PMID 25873050, PMID 26028263, PMID 26063068, PMID 26170014, PMID 26971581, PMID 27053382
K12HD103084 (1), K23GM152933 (1), K23HL132001 (1), P01HD039386 (1), P30CA015083 (1), U01DK071633 (1), U01HD061233 (1)