277 completed. 277 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 277 | Completed 277 |
Follow Shock: new trials by email Literature Review of Shock trials Research Report on Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ Adapted Surviving Sepsis Campaign (SSC) Protocol, Standard Clinical Care - Sepsis, Septic Shock | Not applicable | Completed | Al-Azhar University | 120 | 2026-03-03 | 2026-10-16 |
| Evaluation of Transthoracic Echocardiography Parameters and Their Changes in Blood Donor Volunteers Transthoracic Echocardiography measurements - Hemorrhage, Trauma | Not applicable | Completed | Centre Hospitalier Universitaire de Nīmes | 66 | 2025-10-02 | 2026-10-22 |
| Outcome of Using Hydrocortisone in Early Treatment of Pediatric Septic Shock Intravenous Hydrocortisone, Standard care - Septic Shock | Not applicable | Completed | Muhammad Aamir Latif | 122 | 2025-07-01 | 2026-06-29 |
| Digital Escape Room Game for Hypovolemic Shock Management Play digital escape room game - Nursing Education, Hypovolemic Shock | Not applicable | Completed | Baskent University | 60 | 2025-06-10 | 2026-02-10 |
| The Effect of CUGP Fluid Management in Patients With Sepsis or Septic Shock critical ultrasonography - Sepsis | Not applicable | Completed | Shusheng Li | 118 | 2025-04-01 | 2026-01-30 |
| Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors Weaning critically ill patients from norepinephrine using midodrine as an adjuvant to norepinephrine, Weaning critically ill patients from norepinephrine without use of midodrine as an adjuvant - Shock | Not applicable | Completed | Sohag University | 112 | 2025-03-13 | 2026-05-07 |
| Effect of Lactiplantibacillus Plantarum DAD-13 on Inflammatory Markers in ICU Sepsis Patients Lactiplantibacillus plantarum DAD-13, Placebo - Sepsis, Systemic Inflammatory Response Syndrome (SIRS) | Not applicable | Completed | PT Royal Medikalink Pharmalab | 32 | 2025-02-19 | 2026-10-27 |
| Different Norepinephrine Doses on Accuracy of Peripheral Perfusion Index in Predicting Tissue Perfusion in Septic Shock Patients Group I: Patients will receive norepinephrine <0.15 µg/kg/min, Group II: Patients will receive norepinephrine ≥ 0.15 µg/kg/min - Septic Shock, Peripheral Perfusion Index | Not applicable | Completed | Tanta University | 80 | 2024-10-30 | 2026-01-09 |
| US Guidance for Radial Arterial Puncture in Shock Ultrasound-guided radial arterial puncture for arterial blood gas sampling, Conventional radial artery puncture for arterial blood gas sampling - Shock, Shock Circulatory | Not applicable | Completed | Ismail Erkan Aydin | 100 | 2024-10-01 | 2026-01-23 |
| Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock Crystalloid and blood as resuscitation, crystalloid, blood and low dose of norepinephrine - Mortality Rate, Hemorrhagic Shock | Not applicable | Completed | Tanta University | 60 | 2024-08-30 | 2025-07-11 |
| Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit Intermittent enteral nutrition - Intermittent Fasting, Septic Shock | Not applicable | Completed | University Hospital, Rouen | 174 | 2024-07-09 | 2026-09-28 |
| Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF MEX-CD1 Dialysis - Acute on Chronic Liver Failure, Multiple Organ Failure | Not applicable | Completed | Mexbrain | 11 | 2024-06-21 | 2026-04-29 |
| Effectiveness and Safety of Penehyclidine Hydrochloride for Improving Microcirculatory Dysfunction in Critically Ill Children atropine control group, penehyclidine hydrochloride group - Shock | Not applicable | Completed | Lihua Wen | 98 | 2024-05-08 | 2026-04-09 |
| Effect of Peripheral VA-ECMO Flow Variations on the Pulmonary Arterial Occlusion Pressure (PAPO) in Patients With Refractory Cardiogenic Shock. ECMO-Flow variations - Cardiogenic Shock | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 80 | 2024-03-07 | 2025-04-13 |
| Impact of an Echographic Algorithm on Hemodynamic Optimization in the First 4 Days of Septic Shock Management Echographic hemodynamic algorithm guiding fluid resuscitation - Shock, Septic, Hemodynamic Instability | Not applicable | Completed | Centre Hospitalier Universitaire de Nīmes | 136 | 2024-02-08 | 2026-06-16 |
| Effect of Simulation Application in Septic Shock Management simulation - Septic Shock | Not applicable | Completed | Amasya University | 67 | 2023-11-24 | 2025-06-24 |
| Efficacy and Safety of Early Use PCC in Severe Trauma 4 factor Prothrombin Complex Concentrates - Severe Trauma, Traumatic Shock | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 380 | 2023-08-10 | 2026-04-20 |
| Hemodynamic Effects of Bolus of Ketamine Versus Fentanyl in Patients With Septic Shock Ketamine, Fentanyl - Ketamine, Fentanyl | Not applicable | Completed | Cairo University | 86 | 2023-08-01 | 2023-12-22 |
| Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock NICOM - Sepsis, Hypotension | Not applicable | Completed | University of Minnesota | 251 | 2023-07-31 | 2025-08-27 |
| Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output Monitoring non-invasive cardiac output monitoring, Ultrasonic technology - Septic Shock | Not applicable | Completed | Mai Xiaowei | 60 | 2023-07-05 | 2025-09-22 |
Showing 20 of 277. Sign in to see all of them.
Shock, Septic (138) · Sepsis (85) · Shock, Cardiogenic (23) · Critical Illness (21) · Cytokine Release Syndrome (21) · Systemic Inflammatory Response Syndrome (21) · Multiple Organ Failure (20) · COVID-19 (13) · Hypotension (13) · Acute Kidney Injury (12) · Wounds and Injuries (11) · Respiratory Distress Syndrome (9) · Respiratory Insufficiency (8) · Shock, Hemorrhagic (8)
Pathologic Processes (277) · Pathological Conditions, Signs and Symptoms (277) · Inflammation (187) · Infections (175) · Systemic Inflammatory Response Syndrome (170) · Sepsis (75) · Cardiovascular Diseases (50) · Vascular Diseases (44) · Respiratory Tract Diseases (35) · Heart Diseases (32) · Disease Attributes (31) · Lung Diseases (25) · Infarction (23) · Ischemia (23)
Saline Solution (7) · Standard of Care (6) · Blood Specimen Collection (5) · Hydrocortisone (5) · Norepinephrine (5) · Ascorbic Acid (4) · Ringer's Lactate (4) · Sodium Chloride (4) · Thiamine (4) · Control Groups (3) · Hematologic Tests (3) · Ultrasonography (3) · Albumins (2) · Checklist (2) · Continuous Renal Replacement Therapy (2)
Assistance Publique - Hôpitaux de Paris (9) · Hospices Civils de Lyon (9) · Centre Hospitalier Universitaire de Nīmes (5) · Mayo Clinic (5) · Mahidol University (4) · Southeast University, China (4) · University Hospital, Rouen (4) · Ain Shams University (3) · Center for Sepsis Control and Care, Germany (3) · Central Hospital, Nancy, France (3) · Centre Hospitalier Universitaire Dijon (3) · Denver Health and Hospital Authority (3) · Efferon JSC (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Hospital Universitari de Bellvitge (3)
France (59) · United States (43) · China (21) · Germany (17) · Egypt (12) · Canada (10) · Italy (9) · Brazil (8) · Turkey (Türkiye) (8) · Denmark (7) · Thailand (7) · India (6) · Russia (6) · Czechia (5) · Netherlands (5)
Claire Roger (2) · Frank Bloos, MD, Ph.D. (2) · Holger Thiele, MD (2) · Jean Reignier, MD, PhD (2) · Mahmoud S Abu-Samak, PhD (2) · Massimo Antonelli, MD (2) · Melissa J Parker, MD, MSc (2) · Ognjen Gajic, MD (2) · Sebastien Preau, MD, PhD (2) · Timothy B Curry (2) · Ulrike Holzinger, MD (2) · Alain Combes, MD PhD (1) · Alan Diamond, PhD (1) · Alan E Jones, MD (1)
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2004 (1), 2014 (1), 2019 (1), R01GM104481 (1), R01HD053129 (1), R01HL073233 (1), R25TW009337 (1), UH3HL125119 (1)