46 completed, 17 terminated, 13 unknown, 12 recruiting. 54 Not applicable, 19 Phase 4, 5 Phase 2, 4 Phase 3, 3 Early Phase 1.
Follow Rib Fractures: new trials by email Literature Review of Rib Fractures trials Research Report on Rib Fractures
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Real-time Ultrasound Guidance for Thoracic Epidural Blocks Real-time ultrasound guidance for thoracic epidural catheter placement. - Analgesia, Thoracic Tumors | Withdrawn | University of Chile | 2027-07-01 | 2026-05-19 | ||
| SPSIP vs ESP Block for Analgesia After Rib Fracture Surgery Erector Spinae Plane Block (ESP), Serratus Posterior Superior Intercostal Plane (SPSIP) - Rib Fracture, Postoperative Pain | Not applicable | Not yet recruiting | Antalya City Hospital | 60 | 2026-11-15 | 2026-05-11 |
| Comparison of Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Erector Spinae Plane Block for Acute Pain Management in Patients With Traumatic Rib Fractures Dexmedetomidine with Bupivacaine in ESPB, Dexamethasone with Bupivacaine in ESPB - Rib Fractures, Acute Pain | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-18 |
| Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures Erector spinae plane catheter, Serratus plane catheter - Traumatic Rib Fracture(s), Traumatic Rib Fracture | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 66 | 2026-09-09 | 2026-10-23 |
| Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen - Trauma, Rib Fractures | Not applicable | Not yet recruiting | Loma Linda University | 30 | 2026-09-01 | 2026-02-09 |
| Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures Serratus plane block (continuous or single-shot) - Rib Fractures, Spirometry | Not applicable | Not yet recruiting | Niguarda Hospital | 72 | 2026-06-01 | 2026-04-16 |
| Point of Care Ultrasound (POCUS) for Diagnosis and Treatment of Fractures in the Costal Cartilage Rib Fracture, Cartilage Damage | Not yet recruiting | Sahlgrenska University Hospital | 100 | 2026-06-01 | 2026-04-28 | |
| Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed? Surgical stabilization of two fractures per rib, Surgical stabilization of one fracture per rib. - Rib Fracture Multiple, Flail Chest | Not applicable | Not yet recruiting | Sahlgrenska University Hospital | 100 | 2026-05-05 | 2026-04-28 |
| Zimmer Biomet-RibFix Titan The RibFix Titan™ device should be used within this arm of the study. - Rib Fracture, Rib Fracture Multiple | Recruiting | Zimmer Biomet | 54 | 2026-03-31 | 2026-04-21 | |
| Effectiveness of an Innovative Chest Stabilizer in Rib Fracture Treatment: Impact on Respiratory Function, Complications, and Clinical Outcomes Standard Analgesic Therapy, Innovative Chest Stabilizer - Rib Fractures, Blunt Chest Trauma | Not applicable | Active not recruiting | Caner İşevi, MD | 74 | 2025-12-01 | 2026-10-16 |
| Ultrasound for Diagnosing Costochondral Joint Separation Ultrasound (USG) - Rib Fractures, Thoracic Injuries | Not applicable | Completed | Caner İşevi, MD | 52 | 2025-12-01 | 2026-10-19 |
| Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures Suzetrigine (SUZ), Placebo - Rib Fractures | Phase 4 | Enrolling by invitation | University of California, Irvine | 80 | 2025-11-13 | 2025-12-08 |
| INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures Ropivacaine, Non steroidal anti-inflammatory drug and opioids - Rib Fractures | Phase 4 | Recruiting | Zachary Warriner | 180 | 2025-09-23 | 2025-10-07 |
| Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures Pain Management, Rib Fracture Multiple | Recruiting | Albert Einstein College of Medicine | 220 | 2025-08-10 | 2026-08-19 | |
| Ultrasound-Guided Mid-Point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block for Pain Management in Patients With Multiple Rib Fractures (A Prospective Randomized Double- Blinded, Non-inferiority Trial ) Mid point transverse to pleura block - Rib Fractures | Not applicable | Not yet recruiting | Assiut University | 70 | 2025-06-01 | 2025-05-21 |
| Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia ESP block with bupivacaine, Saline control/sham injection - Rib Fractures | Phase 1 / Phase 2 | Withdrawn | Yale University | 2025-05-01 | 2025-07-01 | |
| Comparison of Continuous Intravenous Lidocaine Infusion Versus ESP Block for Rib Fracture Analgesia Lidocaine IV Infusion, 2% Lidocaine via ESPB - Rib Fractures | Phase 2 | Withdrawn | Stanford University | 2025-05-01 | 2026-05-05 | |
| Deep Breathing Exercises and Incentive Spirometry After Rib Fracture Breathing exercise with spirometry, Breathing exercise with deep breathing method - Rib Fractures, Oxygenation | Not applicable | Recruiting | Samsun University | 104 | 2025-02-15 | 2026-03-16 |
| Impact of Time Interval Between Trauma and Operation on Clinical Outcome in Patients With Delayed Rib Fixation (Nonunion) Rib Fractures, Nonunion of Fracture | Active not recruiting | University Hospital, Basel, Switzerland | 41 | 2025-01-13 | 2025-08-07 | |
| Cryo Rib Fracture Study Cryoablation, ESP Catheter - Rib Fractures | Phase 4 | Recruiting | University of Minnesota | 48 | 2025-01-10 | 2026-02-17 |
Showing 20 of 109. Sign in to see all of them.
Agnosia (14) · Thoracic Injuries (14) · Wounds and Injuries (14) · Acute Pain (13) · Pain (11) · Flail Chest (8) · Fractures, Bone (6) · Multiple Trauma (4) · Chest Pain (3) · Pneumonia (3) · Respiratory Insufficiency (3) · Accidental Injuries (2) · Emergencies (2) · Hemothorax (2)
Fractures, Bone (103) · Thoracic Injuries (95) · Wounds and Injuries (95) · Pathological Conditions, Signs and Symptoms (37) · Neurologic Manifestations (33) · Signs and Symptoms (33) · Nervous System Diseases (17) · Neurobehavioral Manifestations (14) · Pain (14) · Perceptual Disorders (14) · Respiratory Tract Diseases (9) · Pathologic Processes (7) · Lung Diseases (4) · Respiration Disorders (4) · Cardiovascular Diseases (3)
Lidocaine (6) · Acetaminophen (5) · Analgesics, Opioid (4) · Bupivacaine (4) · Ibuprofen (4) · Morphine (4) · Ropivacaine (4) · Anti-Inflammatory Agents, Non-Steroidal (3) · Dexmedetomidine (3) · Ketamine (3) · Naproxen (3) · Saline Solution (3) · Tramadol (3) · dexketoprofen trometamol (3) · Conservative Treatment (2)
Assiut University (4) · Sahlgrenska University Hospital (4) · Stanford University (4) · Ankara City Hospital Bilkent (3) · Caner İşevi, MD (3) · Chang Gung Memorial Hospital (3) · University of California, San Diego (3) · Zimmer Biomet (3) · Brigham and Women's Hospital (2) · Ege University (2) · Kastamonu University (2) · Medical College of Wisconsin (2) · National Taiwan University Hospital (2) · Oregon Health and Science University (2) · Sunnybrook Health Sciences Centre (2)
United States (43) · Turkey (Türkiye) (13) · Canada (6) · Egypt (5) · Taiwan (5) · United Kingdom (5) · Italy (3) · Sweden (3) · Switzerland (3) · China (2) · Germany (2) · Spain (2) · Australia (1) · Chile (1) · Czechia (1)
Eva-Corina Caragounis, MD (2) · Hans Granhed, MD PhD (2) · Joseph D Forrester, MD (2) · Steffen Rosslenbroich, PD Dr. med. (2) · Ahmet Burak Erdem, M.D. (1) · Ajai Malhotra, MD (1) · Amany K Aboelhassan (1) · Andrew Herring, MD (1) · Anthony Iacco, MD (1) · Ariel Knight, MD (1) · Arun Nagdev, MD (1) · Ben Safa, MD (1) · Boyne Bellew (1)
PMID 11837920, PMID 19359920, PMID 19837806, PMID 19889411, PMID 19934395, PMID 20032030, PMID 20078434, PMID 20721716, PMID 21079623, PMID 21111133, PMID 21259336, PMID 22182865, PMID 22978439, PMID 23206720, PMID 23403516, PMID 23706726, PMID 25690384, PMID 27812971, PMID 28372691, PMID 29149140, PMID 29571167, PMID 29578877, PMID 29766081, PMID 30376537, PMID 30548249, PMID 30687939, PMID 31064710, PMID 31858117, PMID 31888765, PMID 31955478, PMID 33950945, PMID 33951024, PMID 34092117, PMID 34789700, PMID 35670748, PMID 35712110, PMID 36056421, PMID 36129720, PMID 36385136, PMID 39691747, PMID 39786597, PMID 39856261, PMID 40299046, PMID 40375321, PMID 40900569, PMID 40912706, PMID 41604277, PMID 41700907, PMID 42159402, PMID 8712986
2019 (1), 2023 (1), T32GM075770 (1)