8 completed, 3 unknown, 1 not yet recruiting, 1 terminated. 7 Not applicable, 2 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 3, Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Flail Chest: new trials by email Literature Review of Flail Chest trials Research Report on Flail Chest
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed? Surgical stabilization of two fractures per rib, Surgical stabilization of one fracture per rib. - Rib Fracture Multiple, Flail Chest | Not applicable | Not yet recruiting | Sahlgrenska University Hospital | 100 | 2026-05-05 | 2026-04-28 |
| Evaluating Improvised Chest Drainage Techniques in Conflict Zones Pneumothorax, Hemothorax | Completed | Sudan Medical Specialization Board | 180 | 2023-06-01 | 2025-01-06 | |
| Thoracic Epidural Analgesia in Flail Chest Morphine Sulfate, Triamcinolone Acetonide - Flail Chest | Phase 2 / Phase 3 | Unknown | Assiut University | 40 | 2018-02-01 | 2018-01-29 |
| Rib Fixation for Clinically Severe Rib Fractures From Trauma Rib Fixation System - Rib Fracture, Flail Chest | Not applicable | Unknown | Darwin Ang | 236 | 2015-04-01 | 2022-05-10 |
| Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma NSAID, Opioids, Thoracic Epidural anaesthesia - Trauma, Flail Chest | Not applicable | Completed | Sahlgrenska University Hospital | 92 | 2014-05-01 | 2019-01-16 |
| Mortality Causes in Rib Surgery Patients Rib fractures manangement - Flail Chest, Rib Fractures | Completed | Caner İşevi, MD | 112 | 2014-01-01 | 2025-01-01 | |
| Treatment of Acute, Unstable Chest Wall Injuries Surgical fixation - Blunt Injury of Thorax, Flail Chest | Not applicable | Unknown | Unity Health Toronto | 207 | 2011-07-01 | 2021-06-18 |
| Flail Chest: A Randomized Controlled Study Operative fixation of flail chest, Non Operative management - Flail Chest | Not applicable | Completed | University of British Columbia | 14 | 2011-04-01 | 2015-05-28 |
| Flail Chest - Rib Fixation Study operative rib fixation, operative rib fixation surgery - Flail Chest | Not applicable | Terminated | Virginia Commonwealth University | 24 | 2010-09-01 | 2015-08-06 |
| MatrixRIB Implants for Surgical Stabilization of Flail Chest Injuries: A Registry MatrixRIB (FDA Approval # K081623) - Flail Chest | Completed | Legacy Biomechanics Laboratory | 20 | 2008-12-01 | 2011-07-06 | |
| Evaluation of Surgical Treatment on Pain and Disability for Chronic, Non-healing Rib Fracture Resection with or without plate fixation - Rib Fracture | Phase 4 | Completed | Oregon Health and Science University | 34 | 2008-10-01 | 2013-03-22 |
| Trial of Operative Fixation of Fractured Ribs in Patients With Flail Chest operative fixation of fractured ribs - Flail Chest, Ventilation | Phase 2 | Completed | The Alfred | 48 | 2007-01-01 | 2012-12-11 |
| Clinical Study of the U-Plate Fracture Repair System to Treat Rib Fractures U-plate fracture repair system - Rib Fracture, Flail Chest | Not applicable | Completed | Oregon Health and Science University | 10 | 2006-11-01 | 2011-07-01 |
Rib Fractures (8) · Thoracic Injuries (4) · Wounds and Injuries (2) · Hemopneumothorax (1) · Hemothorax (1) · Multiple Trauma (1) · Pneumothorax (1) · Respiratory Aspiration (1) · Wounds, Nonpenetrating (1)
Wounds and Injuries (11) · Thoracic Injuries (9) · Fractures, Bone (8) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Respiratory Tract Diseases (2) · Hemorrhage (1) · Pleural Diseases (1) · Respiration Disorders (1)
Morphine (2) · Acetaminophen (1) · Analgesics, Opioid (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Diclofenac (1) · Fracture Fixation, Internal (1) · Ibuprofen (1) · Naproxen (1) · Oxycodone (1) · Palliative Care (1) · Surgical Fixation Devices (1) · Tramadol (1) · Triamcinolone (1) · Triamcinolone Acetonide (1)
Oregon Health and Science University (2) · Sahlgrenska University Hospital (2) · Assiut University (1) · Caner İşevi, MD (1) · Darwin Ang (1) · Legacy Biomechanics Laboratory (1) · Sudan Medical Specialization Board (1) · The Alfred (1) · Unity Health Toronto (1) · University of British Columbia (1) · Virginia Commonwealth University (1)
United States (5) · Canada (2) · Sweden (2) · Australia (1) · Sudan (1)
Ajai K Malhotra, MD (1) · Darwin Ang, MD (1) · Emad Z Saed (1) · Eva-Corina Caragounis, MD (1) · Eva-Corina Caragounis, Ph.D, Ass. Prof (1) · Hans Granhed, MD PhD (1) · Hassan Ali Musa, Consultant (1) · John C Mayberry, MD, FACS (1) · John C. Mayberry, MD (1) · Michael Bottlang, PhD (1) · Michael D McKee, MD, FRCS(C) (1) · Peter J O'Brien, MD (1) · Silvana Marasco, FRACS (1)