37 completed. 37 Phase 1, 17 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 37 | Completed 37 |
| Phase 2 | 17 | Completed 17 |
Follow Periodontitis: new trials by email Literature Review of Periodontitis trials Research Report on Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Microbiological Modulation Of The Oral-Gut Axis After Treatment With Or Without Systemic Use Of Probiotics In Patients With Periodontitis: A Randomized Controlled Clinical Study. Probiotics Bifidobacterium animalis subsp. lactis HN019 - Periodontitis Stage IV, Periodontitis | Phase 1 | Completed | University of Sao Paulo | 40 | 2026-06-25 | 2026-08-28 |
| Injectable Platelet-Rich Fibrin (i-PRF) and Oxygen-Releasing Gel in the Treatment of Stage II Periodontitis. Injectable Platelet-Rich Fibrin (i-PRF, Peroxoborate Oxygen-Releasing Oral Gel, Sterile 0.9% Saline Solution - Stage III Periodontitis | Phase 1 / Phase 2 | Completed | Assiut University | 24 | 2026-01-20 | 2026-11-06 |
| Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail bromelain-quercetin gel, chlorhexidine gel, SRP - Periodontal Pocket | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 30 | 2024-01-04 | 2025-01-15 |
| Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study Diode laser and 3% hydrogen peroxide - Pocket, Periodontal, Periodontal Inflammation | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 10 | 2023-05-28 | 2024-05-08 |
| Clinical Efficacy of Local Delivery of Minocycline and Hyaluronan Gel to Treat Periodontitis in Diabetic Patients Non -surgical treatment and oral hygiene instruction, Application of minocycline and hyaluronic acid gel., local application of placebo gel - Periodontitis and Diabetes, Periodontitis | Phase 1 | Completed | Kafrelsheikh University | 20 | 2023-05-20 | 2025-05-30 |
| Effects of the Adjunctive Use of Hyaluronic Acid-based Gel in the Surgical Periodontal Treatment of Periodontitis open flap debridement and Hyaluronic Acid-Based Gel application, open flap debridement - Periodontitis (Stage 3) | Phase 1 / Phase 2 | Completed | Ordu University | 18 | 2023-04-04 | 2025-02-24 |
| Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy C-PRF - Periodontal Pocket | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 48 | 2023-02-01 | 2023-09-15 |
| Perio. Maint. With Diode LBR Epic Diode, HP, Sham - Chronic Periodontitis | Phase 1 | Completed | Biolase Inc | 14 | 2022-04-01 | 2023-05-03 |
| Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis ozone gel - Periodontal Pocket, Periodontitis | Phase 1 | Completed | Ghufran Falih Hassan | 21 | 2022-03-09 | 2023-06-15 |
| Coconut Oil in Treatment of Periodontitis topical application of coconut oil, scaling and debridement - Periodontal Diseases | Phase 1 | Completed | Misr University for Science and Technology | 34 | 2022-02-15 | 2024-04-25 |
| Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment Atorvastatin Calcium, Scaling and debridement only - Periodontitis | Phase 1 | Completed | Misr University for Science and Technology | 24 | 2021-12-07 | 2022-10-19 |
| The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect RGD Peptide - Periodontitis | Phase 1 / Phase 2 | Completed | Minia University | 45 | 2021-03-15 | 2022-12-16 |
| CBD Effects on Periodontal Health of Patients With Chronic Periodontitis placebo dental gel, placebo toothpaste, Cannabidiol dental gel, Cannabidiol toothpaste, Placebo toothpaste, Corsodyl dental gel - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Palacky University | 90 | 2020-11-05 | 2022-08-11 |
| Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction mesenchymal stem cells, standard treatment - Periodontitis, Chronic | Phase 1 / Phase 2 | Completed | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 10 | 2020-08-03 | 2021-02-09 |
| Concentrated Growth Factors in Treatment of Intrabony Defects in Localized Aggressive Periodontitis GTR, concentrated growth factor - Aggressive Periodontitis | Phase 1 / Phase 2 | Completed | Tanta University | 10 | 2020-07-01 | 2021-09-17 |
| Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients. lemongrass essential oil gel, Placebo, Scaling and root planing - Periodontitis | Phase 1 / Phase 2 | Completed | Alexandria University | 40 | 2020-01-13 | 2021-01-12 |
| The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis Lactobacillus Reuteri Oral Drops, Scaling and root planing - Chronic Periodontitis | Phase 1 | Completed | Tanta University | 12 | 2018-09-01 | 2021-01-06 |
| Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis Ashwagandha, Placebo - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Tatyasaheb Kore Dental College | 50 | 2017-11-30 | 2018-05-23 |
| Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis Saccharomyces Boulardii 250 MG - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Tatyasaheb Kore Dental College | 31 | 2017-11-20 | 2018-05-11 |
| Does Hyaluronic Acid Affect Periodontal Treatment? Scaling and root planning, Hyaluronic acid gel (HA) and SRP, HA mouthrinse and SRP - Periodontitis | Phase 1 | Completed | Yuzuncu Yil University | 24 | 2017-08-30 | 2018-11-27 |
Showing 20 of 37. Sign in to see all of them.
Chronic Periodontitis (11) · Periodontal Pocket (4) · Aggressive Periodontitis (2) · Inflammation (2) · Periapical Periodontitis (2) · Periodontal Attachment Loss (2) · Periodontal Diseases (2) · Alveolar Bone Loss (1) · Bone Diseases, Metabolic (1) · Dental Plaque (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Gingivitis (1) · Plaque, Amyloid (1)
Mouth Diseases (37) · Stomatognathic Diseases (37) · Periodontal Diseases (35) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Chronic Disease (11) · Disease Attributes (11) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Bone Diseases (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Jaw Diseases (2) · Musculoskeletal Diseases (2)
Tooth Exfoliation (9) · Root Planing (4) · Saline Solution (2) · Amoxicillin (1) · Ashwagandha (1) · Atorvastatin (1) · Calcium (1) · Ciprofloxacin (1) · Control Groups (1) · Debridement (1) · Dental Scaling (1) · Diclofenac (1) · Doxycycline (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Hydrogen Peroxide (1)
Krishnadevaraya College of Dental Sciences & Hospital (3) · Tatyasaheb Kore Dental College (3) · Misr University for Science and Technology (2) · Tanta University (2) · Alexandria University (1) · Aristotle University Of Thessaloniki (1) · Assiut University (1) · Biolase Inc (1) · Biomedical Development Corporation (1) · Bulent Ecevit University (1) · Cairo University (1) · Ege University (1) · Geistlich Pharma AG (1) · Ghufran Falih Hassan (1) · Innoventus Project AB (1)
Egypt (8) · India (6) · United States (5) · Turkey (Türkiye) (2) · Belarus (1) · Brazil (1) · Czechia (1) · Greece (1) · Iran (1) · Iraq (1) · Japan (1) · Morocco (1) · Sweden (1)
Dilip Khambete, MDS (2) · Ahmed Y Gamal, PhD (1) · Antonis Konstantinidis, Professor (1) · David L Steed, MD (1) · Donald Clem, DDS (1) · Eralp Buduneli, Proffessor (1) · Hacer Sahin Aydinyurt, Assist Prof (1) · Igor Volotovski, Prof (1) · Jan Hirsch, Prof. (1) · Laurie K McCauley, DDS, PhD (1) · Masoud Saatchi, DDS MS (1) · Michael McGuire, DDS (1) · Nadein E Sharif (1)
PMID 20950166, PMID 21555774, PMID 27660886, PMID 32047601, PMID 32383274, PMID 32436173, PMID 33899259, PMID 3425152, PMID 3793432, PMID 38847929, PMID 39364843, PMID 41269357, PMID 8910821