25 completed, 8 recruiting, 8 unknown, 4 not yet recruiting. 41 Not applicable, 5 Phase 2, 2 Phase 1, 2 Phase 3, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sandwich vs. Mixed Bone Augmentation for Implant Placement Sandwich bone augmentation, Mixed bone augmentation - Peri-implant Bone and Soft Tissues | Not applicable | Not yet recruiting | University of California, San Francisco | 30 | 2026-11-01 | 2026-10-20 |
| Comparison of Three Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation 50:50 Autogenous Bone-Xenograft, 75:25 Autogenous Bone-Xenograft, 25:75 Autogenous Bone-Xenograft - Horizontal Alveolar Ridge Deficiency | Not applicable | Not yet recruiting | Eslam hisham mohamed | 45 | 2026-10-01 | 2026-10-16 |
| Comparison of Two Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation 50:50 Autogenous Bone-Xenograft, 75:25 Autogenous Bone-Xenograft - Horizontal Alveolar Ridge Deficiency | Not applicable | Not yet recruiting | Eslam hisham mohamed | 30 | 2026-10-01 | 2026-10-14 |
| Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction 25% Autogenous + 75% Xenograft, 50% Autogenous + 50% Xenograft - Horizontal Alveolar Ridge Deficiency | Not applicable | Not yet recruiting | salah mohamed mohamed ibrahim ibrahim | 30 | 2026-10-01 | 2026-10-20 |
| Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option? Alveolar Ridge Reconstruction - Tooth Extraction Site Healing, Alveolar Ridge Preservation | Not applicable | Enrolling by invitation | Pontificia Universidade Católica do Rio Grande do Sul | 60 | 2026-05-05 | 2026-09-17 |
| Polynucleotide + Hyaluronic Acid Gel With Xenogeneic Graft for Intrabony Periodontal Defects Polynucleotide and hyaluronic acid-based gel, Control, Xenogeneic bone graft - Periodontitis | Not applicable | Recruiting | University of Sao Paulo | 66 | 2026-02-25 | 2026-04-20 |
| Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators. Engineered cartilage graft (N-TEC), Autologous Matrix Induced Chondrogenesis (AMIC), Patellofemoral Arthroplasty (PFA) - Patellofemoral Osteoarthritis | Phase 2 | Recruiting | University Hospital, Basel, Switzerland | 150 | 2025-07-15 | 2026-03-24 |
| Hyaluronic Acid and Polynucleotides in Ridge Preservation regeneration of post extraction socket with biomaterials - Socket Preservation, Implant-supported Single Crowns | Not applicable | Recruiting | University of Parma | 40 | 2025-06-09 | 2025-09-08 |
| Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects Access flap & surgical debridement, Application of bone substitute material (BioOss Collagen) - Periodontitis, Furcation Defects | Not applicable | Recruiting | Göteborg University | 200 | 2025-03-27 | 2025-08-21 |
| Influence of Healing Time on the Outcomes of Alveolar Ridge Preservation in Periodontally Compromised Extraction Sockets Alveolar ridge preservation - Tooth Loss | Not applicable | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 42 | 2025-02-06 | 2025-02-19 |
| Hyaluronic Acid and Polynucleotides for Supra-bony Defects Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA), Periodontal Access Flap (AF) - Periodontal Diseases, Wound Heal | Not applicable | Recruiting | Queen Mary University of London | 24 | 2024-10-21 | 2026-07-02 |
| Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation? Alveolar ridge preservation - Alveolar Ridge Preservation, Dental Extraction | Not applicable | Recruiting | Nova Southeastern University | 30 | 2024-01-26 | 2025-09-12 |
| AMIC vs. MFx in the Ankle Microfracture (MFx), Chondro-Gide® - Osteochondral Lesion of Talus, Chondral Defect | Not applicable | Withdrawn | Geistlich Pharma AG | 2023-04-28 | 2024-03-18 | |
| AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip Autologous matrix-induced chondrogenesis (AMIC) - Hip Arthroscopy, Articular Cartilage Defect | Phase 1 | Recruiting | McMaster University | 40 | 2023-03-13 | 2026-10-07 |
| Chondro-Gide® Bilayer Collagen Membrane in Knee Cartilage Defect Repair Microfracture, Chondro-Gide bilayer collagen membrane - Cartilage Defects | Not applicable | Terminated | Geistlich Pharma AG | 75 | 2023-03-10 | 2026-03-09 |
| Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation Premolar extraction and socked preservation with L-PRF, Premolar extraction and socked preservation with Xenogenic bone and collagen membrane. - Alveolar Ridge Enlargement | Not applicable | Unknown | Universidad de los Andes, Chile | 38 | 2022-11-01 | 2023-01-05 |
| Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM) Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block - Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement | Phase 4 | Completed | University of Santiago de Compostela | 24 | 2022-06-22 | 2024-11-13 |
| Evaluation of Geistlich Fibro-Gide ® and Autogenous Connective Tissue Graft Prior to Orthodontic Maxillary Expansion. Gingival Phenotype Modification - Thin Gingiva, Transverse Maxillary Deficiency | Not applicable | Withdrawn | University of Alberta | 2022-04-01 | 2024-01-25 | |
| CTG vs VCMX for Peri-implant Soft Tissue Thickness Connective Tissue Graft, Volume-Stable Collagen Matrix - Dental Implants, Peri-Implant Tissues | Not applicable | Completed | Medical Innovation Center Wroclaw | 36 | 2022-01-02 | 2026-01-16 |
| Soft Tissue Changes Around Dental Implants Soft tissue augmentation surgery with CTG, Soft tissue augmentation surgery with Fibro-Gide, No soft tissue augmentation - Tooth Loss, Dental Diseases | Not applicable | Completed | Queen Mary University of London | 18 | 2021-06-21 | 2025-06-08 |
Showing 20 of 52. Sign in to see all of them.
Gingival Recession (6) · Tooth Loss (6) · Fractures, Stress (4) · Periodontal Diseases (4) · Periodontitis (4) · Alveolar Bone Loss (2) · Peri-Implantitis (2) · Anodontia (1) · Bone Resorption (1) · Cartilage Diseases (1) · Chronic Periodontitis (1) · Cysts (1) · Furcation Defects (1) · Intervertebral Disc Degeneration (1) · Knee Injuries (1)
Arthroplasty, Subchondral (3) · Transplantation, Heterologous (3) · taurolidine (2) · Bio-Oss (1) · Bone Substitutes (1) · Bone Transplantation (1) · Guided Tissue Regeneration (1) · Observation (1) · Polydeoxyribonucleotides (1) · Root Planing (1) · Surgical Procedures, Operative (1) · Tolonium Chloride (1) · Tooth Exfoliation (1) · Tooth Extraction (1) · Tooth Movement Techniques (1)
United States (12) · Germany (5) · Italy (5) · Spain (5) · Brazil (4) · Sweden (4) · United Kingdom (4) · Canada (3) · China (2) · Hungary (2) · Netherlands (2) · Poland (2) · Switzerland (2) · Austria (1) · Belgium (1)
Fabiana Martinelli (3) · Michael McGuire, DDS (2) · Antonio Sanz, DDS (1) · Bernd Heinz, Dr (1) · Carlos Garaicoa Pazmino, DDS (1) · Christophe Rignon-Bret, DDS, PhD (1) · Despoina Natsiou Schmiady, Dr. (1) · Donald Clem, DDS (1) · Elena Calciolari, DDS, MS, PhD (1) · Eric T Scheyer, DDS, MS (1) · Eslam Hisham Mohamed, B.Sc. (1) · Giovanni Zucchelli, Prof. (1)
PMID 20061070, PMID 21721988, PMID 22754900, PMID 23050490, PMID 23444157, PMID 23627374, PMID 23730377, PMID 24956099, PMID 26469812, PMID 26547393, PMID 27206923, PMID 28108777, PMID 28304210, PMID 29722835, PMID 29978597, PMID 34169551, PMID 36345818, PMID 38071454, PMID 38489063, PMID 38630297, PMID 39020503, PMID 39342334
2023 (1)