172 completed, 30 terminated, 22 recruiting, 22 unknown. 68 Phase 4, 58 Phase 3, 55 Phase 2, 44 Phase 1, 40 Not applicable.
Follow Ciprofloxacin: new trials by email Literature Review of Ciprofloxacin trials Research Report on Ciprofloxacin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Restrictive Versus Standard Antibiotic Treatment During CAR-T Therapy ceftazidime, ciprofloxacin, Standard-of-Care Antibiotic Strategy - Large B-Cell Lymphoma (LBCL), Multiple Myeloma (MM) | Phase 2 | Not yet recruiting | Zealand University Hospital | 150 | 2027-03-01 | 2026-09-25 |
| Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole - Perianal Abscess, Anal Fistula | Phase 4 | Not yet recruiting | University of Illinois at Chicago | 236 | 2026-10-05 | 2026-09-21 |
| Acetic Acid Ear Drops Versus 0.3 % Ciprofloxacin for Chronic Suppurative Otitis Media. Acetic Acid 2% Ear Drops, Ciprofloxacin 0.3% Otic Solution - Otitis Media Chronic | Not applicable | Not yet recruiting | Dow University of Health Sciences | 146 | 2026-09-23 | 2026-09-22 |
| Prophylactic Antibiotics for Outpatient Urethral Bulking Bactrim (800/160 mg), Keflex (500 mg), Cipro (250 mg), or Macrobid (100mg) - Urinary Tract Infections, Stress Urinary Incontinence | Phase 4 | Recruiting | University of Miami | 150 | 2026-08-01 | 2026-08-20 |
| Non-antibiotic Management in Acute Uncomplicated Diverticulitis Symptomatic treatment (ibuprofen and acetaminophen), Amoxicillin-clavulanate, Ciprofloxacin plus metronidazole - Acute Uncomplicated Diverticulitis | Phase 4 | Withdrawn | Montefiore Medical Center | 2026-07-01 | 2026-08-31 | |
| Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy - Febrile Neutropenia (FN), Pediatric Cancer | Phase 4 | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 136 | 2026-06-01 | 2026-05-15 |
| PANORAMIX : Optimizing 1st-line NALIRIFOX and Exploring Microbiota's Role in 2nd Line Pancreatic Cancer Treatment Nal-IRI, Ciprofloxacin, Paclitaxel - PDAC - Pancreatic Ductal Adenocarcinoma | Phase 2 | Not yet recruiting | GERCOR - Multidisciplinary Oncology Cooperative Group | 206 | 2025-07-01 | 2025-07-01 |
| Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles - Pain, Postoperative, Root Resorption | Not applicable | Enrolling by invitation | Ain Shams University | 108 | 2025-07-01 | 2026-09-29 |
| Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies Ceftazidime, Ciprofloxacin - Neutropenic Fever, Acute Lymphoblastic Leukemia | Phase 4 | Recruiting | Gadjah Mada University | 120 | 2025-06-01 | 2025-08-22 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) Intravenous immunoglobulin, Trimethoprim / Sulfamethoxazole, Amoxicillin clavulanic acid - Myeloma, Non-Hodgkin's Lymphoma | Phase 2 / Phase 3 | Recruiting | Monash University | 900 | 2025-05-06 | 2025-10-07 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig) Trimethoprim Sulfamethoxazole, Amoxycillin/clavulanic acid, Immune Globulin Intravenous - Myeloma, Leukemia | Phase 2 / Phase 3 | Recruiting | Monash University | 900 | 2025-05-06 | 2025-10-07 |
| Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer Standard of Care Chemotherapy + Metronidazole, ciprofloxacin, aspirin - Colorectal Cancer, CRC | Phase 2 | Recruiting | Virginia Commonwealth University | 97 | 2025-03-07 | 2026-08-18 |
| Efficacy of Levofloxacin Versus Ciprofloxacin in the Treatment of Childhood Typhoid Fever Levofloxacin, ciprofloxacin - Typhoid, Fever | Phase 2 | Completed | Avicenna Medical College Lahore | 360 | 2025-02-07 | 2025-09-02 |
| Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium Stibogluconate Ciprofloxacin (BAYO9867), sodium stibogluconate (Pentostam) - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Al-Mustafa University College | 80 | 2025-02-07 | 2025-09-30 |
| Antibiotic Prophylaxis for Neurogenic Bladder Botox Ciprofloxacin, Placebo - Neurogenic Bladder, Post-operative Urinary Tract Infections | Phase 2 | Recruiting | University of Alberta | 160 | 2025-02-01 | 2026-05-07 |
| Shigella Sonnei 53G Human Infection Study in Kenyan Adults Shigella sonnei 53G, Ciprofloxacin 500 mg - Shigellosis | Phase 1 | Recruiting | University of Oxford | 70 | 2025-01-21 | 2025-03-13 |
| Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis Pivmecillinam, Amoxicillin clavulanic acid, Amoxicillin - Cystectomy, Bladder Cancer Requiring Cystectomy | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 248 | 2025-01-07 | 2025-01-09 |
| Glycemia and Antibiotic Efficacy in Diabetic Recurrent UTIs ciprofloxacin 500 mg tablet - T2DM (Type 2 Diabetes Mellitus) | Not applicable | Completed | Al-Mustansiriyah University | 99 | 2024-10-30 | 2025-09-24 |
| Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing nanocurcumin gel, Curcumin Gel, Ciprofloxacin 500 mg +ibuprofen 400mg - Periapical Disease | Phase 2 | Completed | Ain Shams University | 60 | 2024-06-20 | 2025-11-17 |
| Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) WCK 4282 (FEP-TAZ) 4 g, Meropenem, ciprofloxacin 500 mg Optional Oral Switch - Complicated Urinary Tract Infection, Acute Pyelonephritis | Phase 3 | Unknown | Wockhardt | 1004 | 2024-01-01 | 2023-07-17 |
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Urinary Tract Infections (24) · Infections (17) · Crohn Disease (8) · Pulmonary Disease, Chronic Obstructive (8) · Anthrax (7) · Cystic Fibrosis (7) · Neoplasms (7) · Otitis (7) · Otitis Externa (7) · Pneumonia (7) · Sepsis (7) · Bacterial Infections (6) · Febrile Neutropenia (6) · Fever (6) · Lymphoma (6)
Bayer (21) · National Institute of Allergy and Infectious Diseases (NIAID) (7) · Otonomy, Inc. (5) · Iterum Therapeutics, International Limited (4) · Ain Shams University (3) · Assistance Publique - Hôpitaux de Paris (3) · Monash University (3) · Otic Pharma (3) · Poitiers University Hospital (3) · Radboud University Medical Center (3) · University of Chicago (3) · University of North Carolina, Chapel Hill (3) · University of Washington (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Alcon Research (2)
United States (100) · Canada (23) · Germany (15) · Spain (15) · United Kingdom (15) · Netherlands (14) · France (13) · Egypt (12) · Israel (11) · Australia (9) · Brazil (8) · Denmark (8) · Italy (8) · Japan (7) · South Korea (7)
Carl LeBel, PhD (4) · Yehudah Roth, MD (3) · Lindsey Albenberg, DO (2) · Paul Newell, MBBS, MRCP (2) · Zoe McQuilten, Professor (2) · A. Hillary Steinhart, M.D. (1) · Aggelos Pefanis (1) · Agricio N. Crespo, Phd (1) · Ahmed A Elberry, professor (1) · Ahmed AbdelAleem, PhD (1) · Ahmed Dr El Kased, PhD (1)
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