32 active not recruiting. 32 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 32 | Active not recruiting 32 |
Follow Pain: new trials by email Literature Review of Pain trials Research Report on Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Pain Treatment After Total Knee Arthroplasty Suzetrigine, Placebo - Pain | Phase 4 | Active not recruiting | Vertex Pharmaceuticals Incorporated | 66 | 2026-04-24 | 2026-10-28 |
| Analgesic Effect of Superficial Cervical Plexus Block in Postoperative Neck Surgeries superficial cervical plexus block guided by ultrasound with bupivacaine, Paracetamol (500 mg) tablets - Postoperative Pain | Phase 4 | Active not recruiting | Sohag University | 60 | 2026-03-16 | 2026-04-23 |
| EFficacy and safEty of cRisugabalin on nocipLastic paIn in Patients With Parkinson's Disease (RELIEF-PD): a Multicentre, Double-blind, Randomised Controlled Trial Crisugabalin, Placebo - PARKINSON DISEASE (Disorder) | Phase 4 | Active not recruiting | Guangdong Provincial People's Hospital | 166 | 2026-03-13 | 2026-09-14 |
| Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular Disorders Granisetron, lidocaine, occlusal splint - TMD, TMD/Orofacial Pain | Phase 4 | Active not recruiting | Mansoura University | 48 | 2026-01-27 | 2026-03-05 |
| Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies Acetaminophen, NSAID (Ketorolac/Ibuprofen) - Cesarean Delivery, Postpartum Comfort | Phase 4 | Active not recruiting | Thomas Jefferson University | 825 | 2025-08-26 | 2026-08-31 |
| Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression Ketamine, Normal saline - Chronic Pain, Depression | Phase 4 | Active not recruiting | Stanford University | 40 | 2025-01-28 | 2025-10-02 |
| Comparison of Inflammatory Factors, Pain Scale, and Postoperative Recovery Quality (QOR - 15) in Patients Undergoing Colorectal Cancer Surgery with Conventional General Anesthesia Techniques Compared to General Anesthesia Combined with Epidural Anesthesia At Prof. Ngoerah Hospital General Anesthesia (control group), General Anesthesia combined with epidural anesthesia - Inflammation Biomarkers, Quality of Recovery (QoR-15) | Phase 4 | Active not recruiting | Udayana University | 44 | 2024-12-28 | 2025-01-20 |
| Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy Buprenorphine transdermal patch, Tramadol - Postoperative Pain, Shoulder Pain | Phase 4 | Active not recruiting | medina medical center | 70 | 2024-12-01 | 2024-12-20 |
| Personalized Post-Operative Pain Management PGx guided personalized post-operative pain management, Oxycodone, Hydromorphone - Persistent Post Operative Opioid Use, Post-surgical Pain | Phase 4 | Active not recruiting | University of Tennessee Graduate School of Medicine | 208 | 2024-09-25 | 2024-11-01 |
| Scheduled or as Needed Pain Regimen? Motrin and narcotic - Pain, Postoperative | Phase 4 | Active not recruiting | Cape Fear Valley Health System | 90 | 2024-08-01 | 2026-10-21 |
| Intraoperative Sufentanil and Chronic Postsurgical Pain in Non-major Scheduled Abdominal Surgery phone interview - Chronic Postsurgical Pain, Chronic Pain | Phase 4 | Active not recruiting | Centre Hospitalier Universitaire, Amiens | 855 | 2024-06-24 | 2025-11-19 |
| Comparative Study Between Combined Modified Pectoral Nerve Block (PECSΙΙ) and Transversus Thoracic Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia Following Breast Surgeries, (randomized Clinical Trial Study) PECS II block and transverse thoracic plane block, Erector Spinae Plane Block, bupivacaine 0.25 % injection - Post Operative Analgesia, Post Operative Pain | Phase 4 | Active not recruiting | Ain Shams University | 40 | 2024-05-01 | 2025-01-20 |
| Connective Tissue Matrix for Rotator Cuff Tendinopathy CTM Boost, PRP - Tendinopathy, Shoulder Pain | Phase 4 | Active not recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 92 | 2023-12-04 | 2025-09-08 |
| Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis Injection of triamcinolone acetonide into the CMC-1 joint, Multimodal Occupational therapy for CMC-1 joint OA, Placebo - Osteoarthritis Thumb | Phase 4 | Active not recruiting | Diakonhjemmet Hospital | 354 | 2023-11-03 | 2026-11-02 |
| Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery Esketamine - Scoliosis Correction, Esketamine | Phase 4 | Active not recruiting | Peking University First Hospital | 312 | 2023-10-24 | 2026-04-13 |
| No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair Opioids, No opioids - Postoperative Pain, Inguinal Hernia | Phase 4 | Active not recruiting | Clayton Petro | 904 | 2023-07-10 | 2026-03-06 |
| Personalization of Opioid Prescription Following Orthognathic Surgery Personalization of dose and frequency and instituting a tapering protocol of hydromorphone post-orthognathic surgery, Standardized dose and frequency of hydromorphone with no tapering post-orthognathic surgery - Pain, Postoperative, Orthognathic Surgery | Phase 4 | Active not recruiting | Nova Scotia Health Authority | 201 | 2023-04-24 | 2025-08-14 |
| Impact of Mesh Fixation With Tissue Adhesive Use of n-hexyl cyanoacrylate for mesh fixation - Groin Hernia, Hernia, Inguinal | Phase 4 | Active not recruiting | Hospital Universitario de Móstoles | 160 | 2023-03-29 | 2025-05-02 |
| Serratus Planus Block After Minimally Invasive Cardiac Surgery Serratus Anterior Plane Block - Pain, Postoperative | Phase 4 | Active not recruiting | Medical University of Vienna | 66 | 2023-01-01 | 2024-12-24 |
| Utility of CYP2D6 Genotyping to Improve the Efficacy and Safety of Tramadol The patients in experimental group will be genotyped before surgery and treatment will be prescribed according to the CYP2D6 phenotype - Post-surgical Pain, Pain, Acute | Phase 4 | Active not recruiting | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 300 | 2022-10-05 | 2026-08-19 |
Showing 20 of 32. Sign in to see all of them.
Pain, Postoperative (19) · Shoulder Pain (3) · Acute Pain (2) · Chronic Pain (2) · Hernia, Inguinal (2) · Agnosia (1) · Angina Pectoris (1) · Angina, Stable (1) · Colorectal Neoplasms (1) · Coronary Artery Disease (1) · Depression (1) · Diabetes Mellitus, Type 2 (1) · Facial Pain (1) · Inflammation (1)
Neurologic Manifestations (32) · Pathological Conditions, Signs and Symptoms (32) · Signs and Symptoms (32) · Pathologic Processes (21) · Postoperative Complications (19) · Musculoskeletal Diseases (7) · Joint Diseases (6) · Nervous System Diseases (5) · Arthralgia (3) · Hernia (3) · Pathological Conditions, Anatomical (3) · Arthritis (2) · Behavior (2) · Brain Diseases (2)
Acetaminophen (5) · Ibuprofen (5) · Bupivacaine (3) · Oxycodone (3) · Tramadol (3) · Ketorolac (2) · Pregabalin (2) · Analgesics, Opioid (1) · Anesthesia, Epidural (1) · Anesthesia, General (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Aspirin (1) · Calcium Dobesilate (1) · Celecoxib (1) · Control Groups (1)
Ain Shams University (1) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Barts & The London NHS Trust (1) · Brigham and Women's Hospital (1) · Cape Fear Valley Health System (1) · Centre Hospitalier Universitaire, Amiens (1) · Clayton Petro (1) · Diakonhjemmet Hospital (1) · Fundación de Investigación Biomédica - Hospital Universitario de La Princesa (1) · Guangdong Provincial People's Hospital (1) · Henry Ford Health System (1) · Hospital Universitario de Móstoles (1) · Hospital for Special Surgery, New York (1) · Mansoura University (1) · Mayo Clinic (1)
United States (15) · Egypt (3) · Spain (3) · Canada (2) · China (2) · Austria (1) · France (1) · Indonesia (1) · Lebanon (1) · Norway (1) · Saudi Arabia (1) · South Korea (1) · United Kingdom (1)
Amr Alsabbagh, DDS (1) · Bernhard Zapletal, M.D. (1) · Bethany Stetson, MD (1) · Clayton C Petro, MD (1) · Devika Maulik, MD (1) · Dong-Xin Wang, MD,PhD (1) · Elizabeth Bradley, MD (1) · Gary Sutkin, MD (1) · Ida Kristin Haugen, MD, PhD (1) · Jean-Charles Doucet, DMD, MD, MSc (1) · Joseph Maarrawi, MD, PhD (1) · Kelly Van Fossen, DO (1)
PMID 12351295, PMID 2221417, PMID 39207839, PMID 39669005, PMID 41631724, PMID 41988848, PMID 42231178, PMID 6650889
2008 (1), 2023 (1), R01HD111633 (1)