7 unknown, 4 completed, 3 recruiting, 1 not yet recruiting. 4 Not applicable, 3 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Neuroinflammatory Response: new trials by email Literature Review of Neuroinflammatory Response trials Research Report on Neuroinflammatory Response
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease Minocycline, Placebo - Sickle Cell Disease, Cognitive Impairment | Phase 1 | Not yet recruiting | University of Cincinnati | 30 | 2026-12-01 | 2026-11-03 |
| The Effect of Griffonia Simplicifolia on Pain Intensity, Central and Peripheral Sensitization, Painmodulation in Healthy Volunteers Griffonia simplicifolia, Placebo - Chronic Pain, Central Sensitisation | Not applicable | Recruiting | Medical University of Graz | 20 | 2025-09-12 | 2025-06-17 |
| Effect of Boswellia Serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers Boswellia serrata extract, Placebo - Chronic Pain, Central Sensitisation | Not applicable | Recruiting | Medical University of Graz | 12 | 2025-09-01 | 2025-09-24 |
| Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia Dexamethasone, Tocilizumab, Anakinra - Sepsis, Neuroinflammatory Response | Phase 4 | Unknown | Radboud University Medical Center | 52 | 2024-10-24 | 2025-04-04 |
| The Effect of Minimal Flow Anesthesia on Oxidative and Neuroendocrine Stress Response The minimal flow anesthesia with sevoflurane group, The high flow anesthesia with sevoflurane group - Low Flow Anesthesia, Oxidative Stress | Not applicable | Unknown | Bezmialem Vakif University | 2 | 2024-06-30 | 2024-09-25 |
| Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV THC, CBD - HIV, Cannabis | Phase 2 | Recruiting | University of California, San Diego | 90 | 2023-09-01 | 2026-05-01 |
| Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity exposure to organophosphates - Neuroinflammatory Response, Nerve Injury | Unknown | Alexandria University | 90 | 2023-08-01 | 2023-09-01 | |
| Safety & PK of Single Doses of MT1980 MT1980, Placebo - Neuroinflammatory Response | Phase 1 | Completed | Monument Therapeutics Limited | 24 | 2022-06-01 | 2022-11-02 |
| Neuroinflammation and Alzheimer's Pathology in POCD Montreal Cognitive Assessment, Stroop Test, 4AT Delirium - Post-Operative Confusion, Neuroinflammatory Response | Unknown | University of Tennessee Graduate School of Medicine | 120 | 2021-11-01 | 2022-05-18 | |
| Neuroinflammation in Chronic Systemic Symptoms (CSS) Cancer, Cancer Head Neck | Completed | Vanderbilt University Medical Center | 30 | 2021-02-22 | 2023-01-26 | |
| Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 Drug: NA-831 - 0.10 mg/kg, Placebo- 0.10 mg/kg, Drug: NA-831 - 0.20 mg/kg - Covid19, Corona Virus Infection | Phase 1 | Unknown | Biomed Industries, Inc. | 45 | 2020-09-15 | 2020-07-21 |
| The Epidemiology of Parkinson's Disease in Croatia and the Influence of Genetic Factors and Microbiota on the Progression and Treatment Outcomes of the Disease (GiOPARK) Whole-exome sequencing, Microbiota sequencing, Magnetic resonance imaging - Parkinson Disease, Genetic Disease | Unknown | Clinical Hospital Center Rijeka | 300 | 2020-05-01 | 2021-08-17 | |
| The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia Palmithylethanolamid, placebo - Pain, Chronic, Pain, Acute | Not applicable | Completed | Medical University of Graz | 14 | 2020-02-09 | 2023-11-01 |
| The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients. Knee Osteoarthritis, Neuroinflammatory Response | Completed | Kaohsiung Veterans General Hospital. | 60 | 2019-08-07 | 2022-10-06 | |
| Neuroinflammation Markers in Subjects With Psychotic Symptoms Neuroinflammatory Response, Psychosis | Unknown | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | 90 | 2017-11-01 | 2023-04-18 |
Neuroinflammatory Diseases (7) · Chronic Pain (5) · Cognition Disorders (2) · Cognitive Dysfunction (2) · Nerve Degeneration (2) · Acute Pain (1) · Alzheimer Disease (1) · Anemia, Sickle Cell (1) · COVID-19 (1) · Chronic Disease (1) · Coronavirus Infections (1) · Endotoxemia (1) · Genetic Diseases, Inborn (1) · Head and Neck Neoplasms (1) · Marijuana Abuse (1)
Pathological Conditions, Signs and Symptoms (12) · Nervous System Diseases (8) · Pathologic Processes (8) · Inflammation (7) · Mental Disorders (6) · Neurologic Manifestations (5) · Pain (5) · Signs and Symptoms (5) · Neurocognitive Disorders (4) · Brain Diseases (2) · Central Nervous System Diseases (2) · Chemically-Induced Disorders (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Infections (2) · Neurodegenerative Diseases (2)
Cannabidiol (1) · Dexamethasone (1) · Dronabinol (1) · Electroencephalography (1) · Endotoxins (1) · Exome (1) · Frankincense (1) · Griffonia simplicifolia lectins (1) · Interleukin 1 Receptor Antagonist Protein (1) · Lipopolysaccharides (1) · Magnetic Resonance Imaging (1) · Mental Status and Dementia Tests (1) · Minocycline (1) · Sodium Chloride (1) · Stroop Test (1)
Medical University of Graz (3) · Alexandria University (1) · Bezmialem Vakif University (1) · Biomed Industries, Inc. (1) · Clinical Hospital Center Rijeka (1) · Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (1) · Kaohsiung Veterans General Hospital. (1) · Monument Therapeutics Limited (1) · Radboud University Medical Center (1) · University of California, San Diego (1) · University of Cincinnati (1) · University of Tennessee Graduate School of Medicine (1) · Vanderbilt University Medical Center (1)
United States (4) · Austria (3) · Netherlands (2) · Croatia (1) · Egypt (1) · Spain (1) · Taiwan (1) · Turkey (Türkiye) (1)
Chen-Hsiu Chen, Physician (1) · Chih-Chi Tsai, RA (1) · Chun-Hsien Wen, Physician (1) · Lloyd Tran, PhD (1) · Poppy Schoenberg, PhD (1) · Resident Doctor (1) · Robert M Craft, MD (1) · Ronald J Ellis, MD, PhD (1) · Vladimira Vuletic (1) · Yuan-Yi Chia, Director (1)
PMID 20699159, PMID 21899735, PMID 24577438, PMID 24847207, PMID 25984812, PMID 27973687, PMID 32311372, PMID 32922280, PMID 33002723, PMID 34122194, PMID 34447303, PMID 34492237
2023 (1)